Invasive and Non-Invasive Assessment of Cerebral Oxygenation in Patients With Severe Traumatic Brain Injury (TBI)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-07-31

Study Completion Date

2009-04-30

Brief Summary

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The purpose of this study is to investigate the relationship among regional transcranial oxygen saturation (rSO2), brain tissue oxygen pressure (PbtO2) and cerebral perfusion pressure (CPP) in patients with severe traumatic brain injury (TBI).

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Detailed Description

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Experience with rsO2 assessed by near infrared spectroscopy (NIRS) in patients with severe TBI is lacking. Reports about the usefulness of rSO2 are contradictory as regards its technical reliability and clinical value. Continuous time-domain analysis comparing rSO2, PbtO2 and CPP has never been carried out and the correlation among these variables remains largely unknown. A significant association between rSO2 and these clinically important variables would suggest that cerebral oximetry provides relevant data signifying that rSO2 might be a useful tool assessing cerebral oxygenation in selected patients with TBI.

Conditions

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Brain Injuries

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

CROSS_SECTIONAL

Interventions

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transcranial oxygen saturation measurement (INVOS Somanetics 5100C)

rSO2 measurement

Intervention Type DEVICE

Other Intervention Names

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INVOS Somanetics 5100C

Eligibility Criteria

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Inclusion Criteria

* Severe Traumatic Brain Injury (Glasgow Coma Scale \< 9)
* Having an intraparenchymal cerebral ICP/PbtO2 catheter previously inserted.
* Expected length of ICU stay \> 1 days

Exclusion Criteria

* Patient's relatives refusal to patient's inclusion in the study
* Patients necessitating ongoing resuscitation
* End-stage in which death is imminent
* Deficient signal of rSO2 impeding its proper valuation

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Hospitales Universitarios "Virgen del Rocio"