Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Japanese Infants

NCT ID: NCT00574795

Last Updated: 2012-08-08

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

193 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-09-30

Study Completion Date

2008-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to evaluate the safety, tolerability, and immunogenicity of the 13-valent pneumococcal conjugate vaccine (13vPnC) in infants of Japanese descent.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Vaccines, Pneumococcal Conjugate Vaccine

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

13vPnC

"First dose during 2 to 6 months of age Second dose at least 28 days after the first dose Third dose at least 28 days after the second dose Forth dose during 12 to 15 months of age"

Intervention Type BIOLOGICAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Healthy 2 to 6 month-old infant
* Available for entire study period

Exclusion Criteria

* Previous vaccination with licensed or investigational pneumococcal vaccine.
* Previous anaphylactic reaction to any vaccine or vaccine-related component.
* Contraindication to vaccination with a pneumococcal conjugate vaccine.
* Bleeding diathesis or condition associated with prolonged bleeding time that would contraindicate any type of injection.
* Known or suspected immune deficiency or suppression.
Minimum Eligible Age

2 Months

Maximum Eligible Age

6 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Wyeth is now a wholly owned subsidiary of Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Medical Monitor

Role: STUDY_DIRECTOR

Wyeth is now a wholly owned subsidiary of Pfizer

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Nagoya, Aichi-ken, Japan

Site Status

Toyohashi, Aichi-ken, Japan

Site Status

Chiba, Chiba, Japan

Site Status

Matsuyama, Ehime, Japan

Site Status

Fukuoka, Fukuoka, Japan

Site Status

Fukuoka, Fukuoka, Japan

Site Status

Fukuoka, Fukuoka, Japan

Site Status

Fukuoka, Fukuoka, Japan

Site Status

Maebaru-shi, Fukuoka, Japan

Site Status

Asahikawa-shi, Hokkaido, Japan

Site Status

Sapporo, Hokkaido, Japan

Site Status

Sapporo, Hokkaido, Japan

Site Status

Sapporo, Hokkaido, Japan

Site Status

Yokohama, Kanagawa, Japan

Site Status

Yokosuka-shi, Kanagawa, Japan

Site Status

Nangoku-shi, Kochi, Japan

Site Status

Ise-shi, Mie-ken, Japan

Site Status

Tsu, Mie-ken, Japan

Site Status

Yokkaichi-shi, Mie-ken, Japan

Site Status

Kurashiki-shi, Okayama-ken, Japan

Site Status

Meguro-ku, Tokyo, Japan

Site Status

Setagaya-ku, Tokyo, Japan

Site Status

Setagaya-ku, Tokyo, Japan

Site Status

Setagaya-ku, Tokyo, Japan

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Japan

References

Explore related publications, articles, or registry entries linked to this study.

Togashi T, Yamaji M, Thompson A, Giardina PC, Aizawa M, Patterson S, Gruber WC, Scott DA; 3003 Study Group. Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in healthy infants in Japan. Pediatr Infect Dis J. 2013 Sep;32(9):984-9. doi: 10.1097/INF.0b013e318293007e.

Reference Type DERIVED
PMID: 23538524 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

6096A1-3003

Identifier Type: -

Identifier Source: org_study_id