Effect of Mental Stress on Platelet Function

NCT ID: NCT00538707

Last Updated: 2010-02-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-09-30

Study Completion Date

2009-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of the project is to study the acute and chronic effect of mental stress on platelet adhesion and aggregation in two population composed of normal subjects at different ages

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Psychological stress is an important cardiovascular risk factor. Activation of platelets plays an important role in atherosclerosis development and it could be one of the mechanisms linking psychological stress and cardiovascular diseases.

We plan to include 32 healthy subjects. (16 in every group). One group with subjects at age 20 - 49 and the other group with subjects at age 50 - 70 years.

The aim of the study will be to assess the acute and chronic effect of a standard short mental stress (2-minute Bondet Test) on platelet function and of the level of endothelin-1, catecholamines and cortisol. We plan to evaluate if age may play a role in the effect of psychological stress on platelet function.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mental Stress

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Young subjects

Group Type EXPERIMENTAL

2-minute Bondet test

Intervention Type BEHAVIORAL

2-minute Bondet test

Older subjects

Group Type EXPERIMENTAL

2-minute Bondet test

Intervention Type BEHAVIORAL

2-minute Bondet test

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

2-minute Bondet test

2-minute Bondet test

Intervention Type BEHAVIORAL

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

2-minute Bondet light test

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* healthy subjects between 20 - 70 years of age
* written informed consent
* no evidence of diseases

Exclusion Criteria

* pregnancy
* oral contraceptives
* smoking
* use of aspirin or NSAIDs within the last week
* use of benzodiazepines within the last week
* Alcohol or drug abuse
* participation in another study within the last month
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Zurich

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

University Hospital Zurich

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Georg Noll, MD

Role: PRINCIPAL_INVESTIGATOR

University of Zurich

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University Hospital of Zurich

Zurich, , Switzerland

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Switzerland

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

EK-1382

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Mindful Action for Pain
NCT03800654 COMPLETED NA
Neurofeedback for Borderline Personality Disorder
NCT05398627 ACTIVE_NOT_RECRUITING NA
Brain and Meditation (BAM) Study
NCT05215314 COMPLETED NA