A Trial of Epilation Verses Surgery for Minor Trichiasis
NCT ID: NCT00522912
Last Updated: 2012-01-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
1300 participants
INTERVENTIONAL
2008-03-31
2010-05-31
Brief Summary
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In more advanced cases there is a broad consensus that the entropion / trichiasis should be corrected by surgery. In mild cases (minor trichiasis: 1-5 lashes touching the eye) the optimal treatment is uncertain. Some advocate early surgery to turn the eyelid out for any individual with one or more lashes touching any part of the eye. Others consider this to be too early for surgical intervention, as surgery can have a high recurrence rate and complications can arise. Instead, they recommend that minor trichiasis can be managed by epilation (pulling out lashes with forceps). In many endemic regions the uptake of surgery is low, with many patients preferring to epilate for mild disease.
The primary purpose of this study is to compare the outcome of immediate surgery to regular epilation for the management of minor trichiasis. The epilation would be done by a person with good eyesight using proper epilation forceps.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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A
Immediate posterior lamella tarsal rotation surgery for minor trichiasis
Trichiasis surgery
Posterior lamella tarsal rotation
B
Regular epilation by another person
Epilation
Epilation of lashes by another well sighted person using quality epilating forceps
Interventions
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Trichiasis surgery
Posterior lamella tarsal rotation
Epilation
Epilation of lashes by another well sighted person using quality epilating forceps
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients with evidence of corneal damage (will be offered surgery).
18 Years
ALL
No
Sponsors
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London School of Hygiene and Tropical Medicine
OTHER
Responsible Party
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Principal Investigators
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Matthew J Burton, PhD FRCOphth
Role: PRINCIPAL_INVESTIGATOR
London School of Hygiene and Tropical Medicine
Locations
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Bahir Dar Regional Health Bureau
Bahir Dar, Amhara, Ethiopia
Countries
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References
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Rajak SN, Habtamu E, Weiss HA, Kello AB, Gebre T, Genet A, Bailey RL, Mabey DC, Khaw PT, Gilbert CE, Emerson PM, Burton MJ. Surgery versus epilation for the treatment of minor trichiasis in Ethiopia: a randomised controlled noninferiority trial. PLoS Med. 2011 Dec;8(12):e1001136. doi: 10.1371/journal.pmed.1001136. Epub 2011 Dec 13.
Gower EW, Munoz B, Rajak S, Habtamu E, West SK, Merbs SL, Harding JC, Alemayehu W, Callahan EK, Emerson PM, Gebre T, Burton MJ. Pre-operative trichiatic eyelash pattern predicts post-operative trachomatous trichiasis. PLoS Negl Trop Dis. 2019 Oct 7;13(10):e0007637. doi: 10.1371/journal.pntd.0007637. eCollection 2019 Oct.
Rajak SN, Habtamu E, Weiss HA, Bedri A, Zerihun M, Gebre T, Gilbert CE, Emerson PM, Burton MJ. Why do people not attend for treatment for trachomatous trichiasis in Ethiopia? A study of barriers to surgery. PLoS Negl Trop Dis. 2012;6(8):e1766. doi: 10.1371/journal.pntd.0001766. Epub 2012 Aug 28.
Related Links
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Other Identifiers
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5024
Identifier Type: -
Identifier Source: org_study_id
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