Influence of Nutrition on Nasal and Bronchial Affliction in Patients With Allergy on Grass-Pollen

NCT ID: NCT00519740

Last Updated: 2009-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-08-31

Study Completion Date

2008-12-31

Brief Summary

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The study is meant to observe the influence of nutrition on nasal and bronchial discomfort in patients with allergy on grass pollen after specific bronchial provocation. Therefore, the investigators will record the patients' nutrition habits and measure the blood level of long chained polyunsaturated fatty-acids.

Detailed Description

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Conditions

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Bronchial Hyperreactivity Hypersensitivity Allergy Bronchial Asthma

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Interventions

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inhalative specific bronchial provocation with grass-pollen

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age \>12 and \<45 years
* informed consent
* Known allergy on grass-pollen

Exclusion Criteria

* age \<12 and \>45 years
* Clinical asthma requiring regular inhalation
* vital capacity \>80%
* FEV1 \< 75%
* Chronic disease
* pregnancy
* Inhalative or systemic steroid use
* substance abuse
* incapability of understanding the study's purpose and performance
Minimum Eligible Age

12 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Johann Wolfgang Goethe University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Goethe University, Childrens Hospital, Dept of Pulmonology & Allergy

Principal Investigators

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Stefan Zielen, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Goethe University, Department of Pulmonology

Locations

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Goethe University, Department of Pulmonology

Frankfurt am Main, Hesse, Germany

Site Status

Countries

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Germany

References

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Dyerberg J, Bang HO. Lipid metabolism, atherogenesis, and haemostasis in Eskimos: the role of the prostaglandin-3 family. Haemostasis. 1979;8(3-5):227-33. doi: 10.1159/000214314.

Reference Type RESULT
PMID: 511010 (View on PubMed)

Kitz R, Rose MA, Schubert R, Beermann C, Kaufmann A, Bohles HJ, Schulze J, Zielen S. Omega-3 polyunsaturated fatty acids and bronchial inflammation in grass pollen allergy after allergen challenge. Respir Med. 2010 Dec;104(12):1793-8. doi: 10.1016/j.rmed.2010.06.019. Epub 2010 Jul 15.

Reference Type DERIVED
PMID: 20637584 (View on PubMed)

Other Identifiers

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214/06/FFM

Identifier Type: -

Identifier Source: org_study_id

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