Goal-orientated Therapy of Perioperative Disturbance in Hemostasis in Cardiac Surgery

NCT ID: NCT00516126

Last Updated: 2013-01-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-06-30

Study Completion Date

2011-12-31

Brief Summary

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Aim of this study is to investigate whether patients preoperatively treated with acetylsalicylic acid and/or clopidogrel have fewer perioperative bleeding and lower amounts of blood substitution when managed by ROTEM (whole blood coagulation analyzer) and MULTIPLATE (thrombocyte function analyzer).

Detailed Description

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Conditions

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Coronary Artery Bypass Graft Triple Vessel Blood Coagulation Disorders

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Point-of-Care managed

This arm includes all patients in which the hemostatic therapy is guided by POC devices e.g. MULTIPLATE (a platelet function analyzer) or ROTEM (thromboelastometry)

No interventions assigned to this group

Conventional hemostasis lab managed

This arm includes all patients in which the hemostatic therapy is guided by conventional hemostasis laboratory data e.g. INR, aPTT, fibrinogen concentration, platelet count but no POC devices e.g. MULTIPLATE (a platelet function analyzer) or ROTEM (thromboelastometry)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* written consent

Exclusion Criteria

* no written consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

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Daniel Bolliger

PD Dr. Daniel Bolliger

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Miodrag Filipovic, PhD, MD

Role: STUDY_DIRECTOR

Department of Anesthesia, University Hospital Basel, CH-4031 Basel, Switzerland

Locations

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University Hospital Basel

Basel, CH, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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194/06

Identifier Type: -

Identifier Source: org_study_id

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