Epidural Analgesia (EDA) Versus Patient Controlled Analgesia (PCA) in Laparoscopic Colon Surgery
NCT ID: NCT00508300
Last Updated: 2020-08-11
Study Results
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View full resultsBasic Information
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COMPLETED
NA
128 participants
INTERVENTIONAL
2010-01-31
2013-10-31
Brief Summary
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Detailed Description
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Short, both groups are treated according to a recent Fast track protocol. Group A will preoperatively receive a mid thoracic EDA (th 8-9; naropine 0,1%) while group B will receive a PCA (morphine) postoperatively. Both EDA and PCA are removed the afternoon at day 2. Patients with a non-functioning EDA within the first 24h will be crossed over to the PCA group.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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A
Epidural Analgesia (EDA) An epidural catheter was inserted at thoracic level (Th8-Th10) before induction of anesthesia. A bolus of 5 mL of bupivacaine 0.5% was started as soon as the epidural catheter was in place, and a continuous perfusion of bupivacaine 0.5% at 5 mL/hr was initiated until the end of surgical procedure.
Epidural analgesia
Thoracic epidural analgesia until day 2
B
Patient controlled analgesia (PCA) was assured by fentanyl (morphine-based) as needed.
Patient controlled analgesia
Patient controlled analgesia (morphine-based)
Interventions
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Epidural analgesia
Thoracic epidural analgesia until day 2
Patient controlled analgesia
Patient controlled analgesia (morphine-based)
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* No informed consent
* Emergency situation
* Contraindication for EDA (according to local Anesthesia guidelines)
18 Years
ALL
No
Sponsors
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University of Lausanne Hospitals
OTHER
Responsible Party
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Nicolas DEMARTINES
professor of surgery
Principal Investigators
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Nicolas Demartines, MD
Role: STUDY_CHAIR
Department of Visceral Surgery, University Hospital Center, Lausanne, Switzerland
Locations
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Department of Visceral Surgery, University Hospital CHUV, Lausanne
Lausanne, , Switzerland
Countries
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References
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Hubner M, Blanc C, Roulin D, Winiker M, Gander S, Demartines N. Randomized clinical trial on epidural versus patient-controlled analgesia for laparoscopic colorectal surgery within an enhanced recovery pathway. Ann Surg. 2015 Apr;261(4):648-53. doi: 10.1097/SLA.0000000000000838.
Other Identifiers
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P166/07
Identifier Type: -
Identifier Source: org_study_id
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