Open-Label Extension Study Of Safety And Tolerability Of Pregabalin In Pediatric Patients With Partial-Onset Seizures

NCT ID: NCT00448916

Last Updated: 2021-01-25

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-05-31

Study Completion Date

2013-10-31

Brief Summary

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The study will evaluate the long-term safety and tolerability of pregabalin in pediatric patients, age 1 month through 16 years, with partial onset seizures.

Detailed Description

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Conditions

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Epilepsies, Partial

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Pregabalin

Orally-administered pregabalin

Group Type EXPERIMENTAL

Pregabalin

Intervention Type DRUG

Orally-administered pregabalin

Interventions

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Pregabalin

Orally-administered pregabalin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Partial onset seizures, incompletely controlled on 1-3 medications
* At least 1 seizure per 28 days, on average
* Completion of study A0081074

Exclusion Criteria

* Primary generalized seizures
* Progressive CNS pathology
* Failure to tolerate pregabalin in study A0081074
Minimum Eligible Age

1 Month

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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University of South Alabama

Mobile, Alabama, United States

Site Status

University of South Alabama Department of Neurology

Mobile, Alabama, United States

Site Status

Phoenix Children's Hospital

Phoenix, Arizona, United States

Site Status

The Children's Clinica of Jonesboro, P.A

Jonesboro, Arkansas, United States

Site Status

Clinical Study Centers, L. L. C.

Little Rock, Arkansas, United States

Site Status

UCSF Neurology Clinic

San Francisco, California, United States

Site Status

Child Neurology Center of Northwest Florida

Gulf Breeze, Florida, United States

Site Status

The Office of Sergio J Jacinto, MD

Tampa, Florida, United States

Site Status

Pediatric Epilepsy & Neurology Specialists

Tampa, Florida, United States

Site Status

St. John's Clinic

Springfield, Missouri, United States

Site Status

St. John's Hospital

Springfield, Missouri, United States

Site Status

Women and Children's Hospital of Buffalo

Buffalo, New York, United States

Site Status

Duke University Medical Center

Durham, North Carolina, United States

Site Status

Baylor College of Medicine - Texas Children's Hospital

Houston, Texas, United States

Site Status

Texas Children's Hospital

Houston, Texas, United States

Site Status

Road Runner Research, Ltd.

San Antonio, Texas, United States

Site Status

Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde

Guadalajara, Jalisco, Mexico

Site Status

Yonsei University College of Medicine Severance Hospital / Department of Pediatric Neurology

Seoul, , South Korea

Site Status

Countries

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United States Mexico South Korea

Related Links

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Other Identifiers

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2010-020731-39

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

A0081075

Identifier Type: -

Identifier Source: org_study_id

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