Randomized, Controlled, Open, Comparative Intervention Study for Obesity Prevention in Children

NCT ID: NCT00438555

Last Updated: 2015-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

248 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-10-31

Study Completion Date

2014-12-31

Brief Summary

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Randomized, controlled, open, comparative intervention study in 270 children at risk for obesity.Patients will be randomly allocated into one of two behavior intervention groups or control group in ratio of 1:1:1.The study will consist of two main periods: an intervention period of 3 months followed by 21 months of a follow up period. During the intervention period, participants (parents or both parents and children, depending on randomization) will attend a behavior intervention program once a week, each session will last one hour and would be guided by dietician and psychologist. Follow up visits will be performed at the clinic (for participants in al 3 groups) at months 0, 3, 12 and 24.

Detailed Description

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Randomized, controlled, open, comparative intervention study in 270 children at risk for obesity.

Objectives:

1. To develop an intervention program for obesity prevention in children aged 5-10 years old, who are at risk to develop obesity
2. To compare between the efficacy of two different intervention programs and a control group in preventing obesity in the short and the long term.
3. To evaluate the role and significance of including parents in an intervention program for obesity prevention.
4. To identify demographic parameters, lifestyle characteristic and biochemical markers that predict the risk of developing obesity and the response for treatment.

Randomization:

Patients will be randomly allocated into one of two intervention groups or control group in ratio of 1:1:1. Each group will contain 12-15 participants.

Intervention groups:

1. parent's group- only parents will take part at the intervention program.
2. Parents and children group- both children and parents will take part at the intervention program, in two separate sessions.

Methods:

1. The study will be consist of two main periods: an intervention period of 3 months followed by 21 months of a follow up period. During the intervention period, participants (parents or both parents and children, depending on randomization) will attend a behavior intervention program once a week, each session will last one hour and would be guided by dietician and psychologist. Follow up visits will be performed at the clinic (for participants in all 3 groups) at months 0, 3, 12 and 24.
2. Height, weight, fat mass and waist circumference will be measured at 0, 3, 12 and 24 month. Height and weight of parents will also be measured at these visits.
3. Physical examination will be performed at 0, 3, 12 and 24 month.
4. Psychological and nutritional questionnaire (depression, quality of life and self estimation) will be filled at 0, 3, 12 and 24 month.
5. Fasting blood tests for: chemistry, hematology, lipids, glucose, insulin, TSH, adiponectin, IL-6 and TNFα will be performed at 0, 3, 12 and 24 month.

Conditions

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Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Parent's group

3 months workshop of parents intervention, guided by dietician and phycologist

Group Type EXPERIMENTAL

Parent's group

Intervention Type BEHAVIORAL

3 months workshop of parents intervention, guided by dietician and phycologist

Parents and children group

3 months workshops of parents and children intervention, guided by dietician and phycologist

Group Type EXPERIMENTAL

Parents and children group

Intervention Type BEHAVIORAL

3 months workshops of parents and children intervention, guided by dietician and phycologist

Control group

control group, no intervention, medical follow up only

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Parents and children group

3 months workshops of parents and children intervention, guided by dietician and phycologist

Intervention Type BEHAVIORAL

Parent's group

3 months workshop of parents intervention, guided by dietician and phycologist

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Children aged 5-10 years old
* BMI in 85-98 percentile
* Both parents signing informed consent form

Exclusion Criteria

* Chronic disease or chronic use of medication
* Incapability to perform all study procedure
Minimum Eligible Age

5 Years

Maximum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Pfizer

INDUSTRY

Sponsor Role collaborator

Rabin Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Moshe Phillip, Prof, MD

Role: PRINCIPAL_INVESTIGATOR

Schneider Children Medical Center

Joseph Meyerovitch, Dr, MD

Role: PRINCIPAL_INVESTIGATOR

Schneider Children Medical Center

Locations

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schneider children medical center of Israel

Petah Tikva, , Israel

Site Status

Countries

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Israel

Other Identifiers

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rmc004055ctil

Identifier Type: -

Identifier Source: org_study_id

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