Effect of Physical Activity an Stress in Children

NCT ID: NCT01693926

Last Updated: 2020-03-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2012-09-30
• Study Completion Date: 2017-12-31

Brief Summary

The objective of the study is to evaluate the impact of physical activity in obese and nonobese prepubertal children on:

1. biological stress responses during a psychosocial stress test

2. snacking and feeling of hunger in response to the same psychosocial stress test

3. the moderating factor of attachment on the biological stress responses and on snacking

Children will be investigated on one study day during 3.5 hours.

Detailed Description

Hypotheses In this study, 3 primary hypotheses will be tested.

1. Moderate physical activity during 25 min in children decreases the cortisol levels in response to the Trier Social Stress Test TSST-C (for children).

2. Moderate physical activity during 25 min in children decreases the snacking (calorie consumption when corrected for expenditure and switch in quality of food intake) in response to the Trier Social Stress Test TSST-C (for children).

3. A secure attachment will be a moderating factor for the general increase in cortisol and the snacking in response to the psychosocial stress test (Trier Social Stress Test TSST-C).

Secondary objectives:

1. To test if the impact of physical activity on stress responses and snacking differs between obese and non-obese children

2. To test the impact of physical activity on the cardiovascular stress reactivity (blood pressure, heart rate) and the perceived stress (scale) in response to the Trier Social Stress Test TSST-C?

3. To test if the stress reactivity and its modulation by physical activity is different in anxious and in impulsives/labile children

4. To test if serious life events and parental worries and parental educational style influence the stress reactivity

Conditions

Obesity; Children; Physical Activity; Stress; Snacking

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Acute physical activity intervention

25 min of moderate physical activity

Group Type: EXPERIMENTAL

Acute physical activity intervention

Intervention Type: BEHAVIORAL

25 min of physical activity. The placebo arm will have 25 min of reading.

Placebo

25 min of reading (instead of physical activity)

Group Type: PLACEBO_COMPARATOR

placebo

Intervention Type: BEHAVIORAL

Interventions

Acute physical activity intervention

25 min of physical activity. The placebo arm will have 25 min of reading.

Intervention Type: BEHAVIORAL

placebo

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• 7-10 year old children

Exclusion Criteria

• Severe illness
• Medications interfering with study

• Minimum Eligible Age: 7 Years
• Maximum Eligible Age: 10 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Lausanne Hospitals

OTHER

Sponsor Role: lead

Responsible Party

Jardena Puder

Medin adjoint

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Univeristy of Lausanne, SUPEA

Lausanne, Canton of Vaud, Switzerland

Countries

Switzerland

References

Horsch A, Wobmann M, Kriemler S, Munsch S, Borloz S, Balz A, Marques-Vidal P, Borghini A, Puder JJ. Impact of physical activity on energy balance, food intake and choice in normal weight and obese children in the setting of acute social stress: a randomized controlled trial. BMC Pediatr. 2015 Feb 19;15:12. doi: 10.1186/s12887-015-0326-7.

Reference Type: DERIVED

PMID: 25879821 (View on PubMed)

Other Identifiers

286/12

Identifier Type: -

Identifier Source: org_study_id