Malignant Wounds, Wound Treatment, Psycho-Social Support and Relaxation Therapy

NCT ID: NCT00435474

Last Updated: 2009-06-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-04-30

Study Completion Date

2009-05-31

Brief Summary

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The purpose of this study is to investigate whether treatment for cancer patients with malignant wounds can improve (wound healing/wound size, odor, infection, seepage, pain) through comparing the effects of two multidimensional interventions including wound treatment, psycho-social support and relaxation therapy.

Detailed Description

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Objective: To investigate whether treatment for cancer patients with malignant wounds can improve (wound healing/wound size, odor, infection, seepage, pain) through comparing the effects of two multidimensional interventions:

1. wound treatment (silver product, alginate and foam dressing \>\< honey product, alginate and foam dressing) in combination with,
2. psycho-social support (based on the structure in cognitive therapy) and
3. relaxation therapy.

Furthermore to investigate coping strategies, body image, stigma and quality of life in cancer patients with malignant wounds.

Design: A hypothesis testing prospective randomized clinical intervention study (n=70) and an explorative qualitative interview study

Method: Digital photographing, measurement of wound size with Quantify-Image-One, wound morphology registration (the extent of malodour, infection, seepage, bleeding, pain, the healing process), grafting, VAS-score, quality of life questionnaire (EORTC-QLQ-C30, DLQI), Hospital Anxiety and Depression Scale (HAD), Mental Adjustment to Cancer (MAC), interview.

Patients will fill out a diary focusing on wound related problems.

Perspectives: The results will determine whether the honey treatment is an improvement, and whether the silver treatment has statistical and clinical significance.

The qualitative study will contribute new knowledge about conditions of life for cancer patients with cancer wounds, their feelings and impositions.

In spite of proving positive effect, the project will contribute with new required knowledge on treatment and support for cancer patients suffering from malignant wounds.

Conditions

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Cancer Malignant Wounds

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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1

Silver product

Group Type ACTIVE_COMPARATOR

Wound treatment

Intervention Type PROCEDURE

wound treatment (silver product, alginate and foam dressing)

psycho-social support

Intervention Type OTHER

psycho-social support (based on the structure in cognitive therapy)

relaxation therapy

Intervention Type OTHER

relaxation therapy

2

Honey product

Group Type EXPERIMENTAL

wound treatment

Intervention Type PROCEDURE

wound treatment (honey product, alginate and foam dressing)

psycho-social support

Intervention Type OTHER

psycho-social support (based on the structure in cognitive therapy)

relaxation therapy

Intervention Type OTHER

relaxation therapy

Interventions

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Wound treatment

wound treatment (silver product, alginate and foam dressing)

Intervention Type PROCEDURE

wound treatment

wound treatment (honey product, alginate and foam dressing)

Intervention Type PROCEDURE

psycho-social support

psycho-social support (based on the structure in cognitive therapy)

Intervention Type OTHER

relaxation therapy

relaxation therapy

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Cancer with evidence of disease.
* Cancer wound \>2 cm.
* Receiving antineoplasm treatment.
* \> 18 years.
* Receiving antineoplasm treatment in out-patient clinic.
* Read, speak and write Danish.

Exclusion Criteria

* No radiation therapy the last 6 month (on the wound).
* Life expectancy \> 3 month.
* Not psychotic.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Principal Investigators

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Lis Adamsen, Professor

Role: STUDY_CHAIR

Copenhagen University. Faculty of health Sciences, Denmark

Locations

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Rigshospitalet, University hospital of Copenhagen. Oncology department

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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kf 0102006-5491

Identifier Type: -

Identifier Source: org_study_id

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