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A Randomised Controlled Trial of Face Masks and Hand Hygiene in Reducing Influenza Transmission in Households

NCT ID: NCT00425893

Last Updated: 2012-04-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

6069 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-02-28

Study Completion Date

2008-11-30

Brief Summary

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This study will test the effectiveness of face masks and hand cleaning in preventing the spread of influenza within households

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Detailed Description

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Randomised controlled trial of surgical masks and alcohol hand wash among approximately 6069 Hong Kong residents who have a household member diagnosed with influenza. Influenza in index member and secondary infection will be documented with rapid influenza tests and PCR. Minimal risk to participants.

Conditions

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Influenza

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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1

health education

Group Type ACTIVE_COMPARATOR

health education

Intervention Type OTHER

Proper nutrition, etc.

2

hand hygiene

Group Type EXPERIMENTAL

hand hygiene

Intervention Type BEHAVIORAL

alcohol-based hand wash

3

masks and hand hygiene

Group Type EXPERIMENTAL

hand hygiene

Intervention Type BEHAVIORAL

alcohol-based hand wash

face masks

Intervention Type DEVICE

face masks

Interventions

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hand hygiene

alcohol-based hand wash

Intervention Type BEHAVIORAL

health education

Proper nutrition, etc.

Intervention Type OTHER

face masks

face masks

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Member of family with influenza infected member

Exclusion Criteria

* Age less than 2 yr
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The University of Hong Kong

OTHER

Sponsor Role collaborator

Centers for Disease Control and Prevention

FED

Sponsor Role lead

Responsible Party

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CDC

Principal Investigators

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Benjamin J Cowling, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Locations

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University of Hong Kong

Hong Kong, Hong Kong, China

Site Status

Countries

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China

References

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Cowling BJ, Chan KH, Fang VJ, Cheng CK, Fung RO, Wai W, Sin J, Seto WH, Yung R, Chu DW, Chiu BC, Lee PW, Chiu MC, Lee HC, Uyeki TM, Houck PM, Peiris JS, Leung GM. Facemasks and hand hygiene to prevent influenza transmission in households: a cluster randomized trial. Ann Intern Med. 2009 Oct 6;151(7):437-46. doi: 10.7326/0003-4819-151-7-200910060-00142. Epub 2009 Aug 3.

Reference Type DERIVED
PMID: 19652172 (View on PubMed)

Cowling BJ, Fung RO, Cheng CK, Fang VJ, Chan KH, Seto WH, Yung R, Chiu B, Lee P, Uyeki TM, Houck PM, Peiris JS, Leung GM. Preliminary findings of a randomized trial of non-pharmaceutical interventions to prevent influenza transmission in households. PLoS One. 2008 May 7;3(5):e2101. doi: 10.1371/journal.pone.0002101.

Reference Type DERIVED
PMID: 18461182 (View on PubMed)

Other Identifiers

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CDC Grant# 1 U01 CI000439-01

Identifier Type: -

Identifier Source: secondary_id

CDC-NCCID-UCI000439A

Identifier Type: -

Identifier Source: org_study_id

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