Comparison of Misoprostol and PGE2 Gel for Induction of Labour in Women With Premature Rupture of Membranes at Term
NCT ID: NCT00355966
Last Updated: 2010-03-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
212 participants
INTERVENTIONAL
2006-08-31
2008-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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A
In group A, immediate induction of labour will be done by intravaginal misoprostol 25 microgram 4 hourly , a maximum of 5 doses .
Misoprostol
In one group of women immediate induction of labour will be done by intravaginal misoprostol 25 microgram 4 hourly , a maximum of 5 doses .
B
In Group B immediate induction of labour will be done by application of vaginal PGE2 gel 0.5 gm at an interval of 6 hours , a maximum of 2 doses.
PGE2 gel
In other group immediate induction of labour will be done by intravaginal application of PGE2 gel 0.5 mg at an interval of 6 hours , a maximum of 2 doses.
Interventions
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Misoprostol
In one group of women immediate induction of labour will be done by intravaginal misoprostol 25 microgram 4 hourly , a maximum of 5 doses .
PGE2 gel
In other group immediate induction of labour will be done by intravaginal application of PGE2 gel 0.5 mg at an interval of 6 hours , a maximum of 2 doses.
Eligibility Criteria
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Inclusion Criteria
* Single live fetus in cephalic presentation
Exclusion Criteria
* Women with contraindication of induction of labour
* Women with previous caesarean section or uterine surgery
FEMALE
No
Sponsors
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Nilratan Sircar Medical College
OTHER_GOV
Responsible Party
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Nilratan Sircar Medical College , Kolkata
Principal Investigators
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Snehamay Chaudhuri, MBBS,MD,DNB
Role: PRINCIPAL_INVESTIGATOR
NRS Medical College , Kolkata, India
Locations
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NRS Medicl College,138 AJC Bose Road
Kolkata, West Bengal, India
Countries
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Related Links
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Chaudhuri S, Mitra SN, Biswas PK, Bhattcharyya S.Pramature rupture of membranes at term: Immediate induction with PGE2 gel compared with delayed induction with oxytocin,Ind J Obstet Gynecol Vol56,no 3; 2006,224-229
Other Identifiers
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1-Chaudhuri
Identifier Type: -
Identifier Source: org_study_id
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