In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

NCT ID: NCT00302874

Last Updated: 2007-03-26

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 400 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2003-02-28
• Study Completion Date: 2004-10-31

Brief Summary

To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.

The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients.

Study Information:

• All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study.
• At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer.
• During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia.
• During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol.
• During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol.
• Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.

Conditions

Diabetes; Hyperglycemia

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Blinding Strategy: NONE

Interventions

Implementation of a protocol for treatment of hyperglycemia

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• All patients admitted to the internal medicine ward with hyperglycemia

Exclusion Criteria

• Patients admitted due to hypoglycemia, hyperosmolar state, and ketoacidosis

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hadassah Medical Organization

OTHER

Sponsor Role: lead

Principal Investigators

Gil Leibowitz, MD

Role: PRINCIPAL_INVESTIGATOR

Hadassah Medical Organization

Locations

Hadassah Medical Organization

Jerusalem, , Israel

Countries

Israel

Other Identifiers

gil362-HMO-CTIL

Identifier Type: -

Identifier Source: org_study_id