Follow up Trial for Keppra (Levetiracetam) as Monotherapy in Patients With Newly Diagnosed Epilepsy Coming From N01175 (NCT00175903).

NCT ID: NCT00291655

Last Updated: 2015-05-18

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-06-30

Study Completion Date

2008-04-30

Brief Summary

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For ethical reasons to give opportunity for adult subjects (≥16 or 18 years) suffering from newly diagnosed epilepsy who completed the therapeutic confirmatory, open-label trial N01175 (NCT00175903) conducted with levetiracetam in monotherapy and who benefited from the treatment, to receive treatment with levetiracetam until the monotherapy indication for levetiracetam is granted in Europe.

To continue to assess safety of levetiracetam as per adverse event reporting and observation of weight changes.

Detailed Description

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Conditions

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Epilepsy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Levetiracetam (LEV)

Group Type EXPERIMENTAL

Levetiracetam

Intervention Type DRUG

500 mg oral tablets,1000 - 3000 mg/day, twice a day (BID), duration of the study

Interventions

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Levetiracetam

500 mg oral tablets,1000 - 3000 mg/day, twice a day (BID), duration of the study

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Male/female adult subjects (≥ 16 or 18 years)
* Diagnosis of epilepsy (all types of seizures may be included)
* Subjects who completed N01175 (NCT00175903) trial and benefited from levetiracetam monotherapy

Exclusion Criteria

* Subjects withdrawn from N01175 (NCT00175903) trial for any reason
* Subjects who received treatment other than levetiracetam in N01175 (NCT00175903) trial
* Subject requiring add-on antiepileptic treatment
* Subjects from countries where levetiracetam is authorized for use as monotherapy in epilepsy treatment
* Sexually active woman with childbearing potential who is not using a medically accepted birth control method
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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UCB Pharma

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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UCB Clinical Trial Call Center

Role: STUDY_DIRECTOR

+1 877 822 9493 (UCB)

Locations

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Bruges, , Belgium

Site Status

Edegem, , Belgium

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Ghent, , Belgium

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Haine-Saint-Paul, , Belgium

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Jette, , Belgium

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Kortrijk, , Belgium

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Leuven, , Belgium

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Ostend, , Belgium

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Sofia, , Bulgaria

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Varna, , Bulgaria

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Hus (helsinki), , Finland

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Kuopio, , Finland

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Tampere, , Finland

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Blaye, , France

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Bordeaux, , France

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Brest, , France

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Carcassonne, , France

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Cherbourg, , France

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Lille, , France

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Lyon, , France

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Nancy, , France

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Rennes, , France

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Saint-Brieuc, , France

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Saint-Quentin, , France

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Toulouse, , France

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Valenciennes, , France

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Częstochowa, , Poland

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Krakow, , Poland

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Olsztyn, , Poland

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Poznan, , Poland

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Warsaw, , Poland

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Biel, , Switzerland

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Lausanne, , Switzerland

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Sankt Gallen, , Switzerland

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Zurich, , Switzerland

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Countries

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Belgium Bulgaria Finland France Poland Switzerland

Related Links

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Other Identifiers

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EUDRACT NUMBER: 2006-000173-29

Identifier Type: -

Identifier Source: secondary_id

N01237

Identifier Type: -

Identifier Source: org_study_id

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