Functional Surface Electromyogram of Knee Extensors in Healthy Humans and Patients With Patella-dislocation.

NCT ID: NCT00288847

Last Updated: 2015-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

15 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-11-30

Study Completion Date

2007-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The activation of the knee extensors in adults after patella dislocation.

The kneecap can dislocate due to an accident or also only due to an interior turn in the stretched knee joint out of its sliding bearing. E. Arendt (Arendt 2002) wrote an overview work, in which possible causes and working methods to the patella dislocation are discussed. Despite almost one hundred quotations the authors are not able find the causes and the possible treatment concepts. The study will examined healthy adults (25 female and 25 men) and 25 patients with patella dislocation by a routine applied clinical gait analysis and surface EMG (after the European SENIAM guidelines) iin the Laboratory for Gait Analysis Basel of the Children's University Hospital Basel. The combination of gait analysis and the surface EMG with Wavelet analysis may objectify possible reasons for a patella dislocation

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Introduction The kneecap can dislocate due to an accident or also only due to an interior turn in the stretched knee joint out of its sliding bearing. E. Arendt (Arendt 2002) wrote an overview work, in which possible causes and working methods to the patella dislocation are discussed. Despite almost one hundred quotations the authors are not able find the causes and the possible treatment concepts. The study will examined healthy adults (25 female and 25 men) and 25 patients with patella dislocation by a routine applied clinical gait analysis and surface EMG (after the European SENIAM guidelines) in the Laboratory for Gait Analysis Basel of the Children's University Hospital Basel. The combination of gait analysis and the surface EMG with Wavelet analysis may objectify possible reasons for a patella dislocation and compare the intensity pattern of the EMG between the groups.

Method All subjects (healthy and patients with a patella dislocation) will be prior to the study informed about the study and sign the consent from

The investigation will include the following tasks:

* Preparation of the subject for a clinical gait analysis with placing reflecting marker on the lower body according to the maker setup of Davis et al. (Davis III et al., 1991.
* Preparation of the subject for a surface EMG of the muscles: gastrocnemius medialis, tibialis anterior, vastus medialis, vastus lateralis, rectus femoris, biceps femoris, semitendinosus according to the SENIAM-Standard.
* Measurements: 10 trials of level walking in self selected speed and 3 times 5 single leg quads on the force plate.
* System: VICON 460 (6 Cameras, 120 Hz, Oxford Metrics Ltd., UK).
* EMG-System: Zebris, Tuebingen, Germany; Amplifiers: Biovision, Wehrheim, Germany, EMG-Electrodes: Bipolar Ag/AgCl Surface Electrodes Noraxon, Sampling rate: 2520 Hz
* Data analysis: Kinetic-and kinematic data with the Vicon-Software, EMG-Data with Wavelet Package (Biomechanigg, Calgary, Canada)
* Statistical Analysis: ANVOA

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Patella-Dislocation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient: Patella Dislocation before surgery
* Control: healthy

Exclusion Criteria

* Patient: Patella Dislocation not able to walk,
* Patient: using orthosis or crutches
* Control: knee injury (e.g. ACL-rupture)
* Control: leg surgery in the last 5 years
* Control: sport injury in the last 6 month (e.g. Muscle pulling)
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Lab. for Orthopaedic Biomechanics, University of Basel

OTHER

Sponsor Role collaborator

University Children's Hospital Basel

OTHER

Sponsor Role collaborator

University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Beat Goepfert, MEng

Role: PRINCIPAL_INVESTIGATOR

Lab. for Orthopaedic Biomechanics, University of Basel

Dieter Wirz, MD

Role: PRINCIPAL_INVESTIGATOR

Lab. for Orthopaedic Biomechanics, University of Basel

Alma U Daniels, Ph.D.

Role: STUDY_CHAIR

Lab. for Orthopaedic Biomechanics, University of Basel

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Lab. for Orthopaedic Biomechanics, University of Basel

Basel, Canton of Basel-City, Switzerland

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Switzerland

References

Explore related publications, articles, or registry entries linked to this study.

Von Tscharner V, Goepfert B. Estimation of the interplay between groups of fast and slow muscle fibers of the tibialis anterior and gastrocnemius muscle while running. J Electromyogr Kinesiol. 2006 Apr;16(2):188-97. doi: 10.1016/j.jelekin.2005.07.004. Epub 2005 Sep 1.

Reference Type BACKGROUND
PMID: 16139523 (View on PubMed)

von Tscharner V, Goepfert B. Gender dependent EMGs of runners resolved by time/frequency and principal pattern analysis. J Electromyogr Kinesiol. 2003 Jun;13(3):253-72. doi: 10.1016/s1050-6411(02)00111-6.

Reference Type BACKGROUND
PMID: 12706605 (View on PubMed)

von Tscharner V, Goepfert B, Nigg BM. Changes in EMG signals for the muscle tibialis anterior while running barefoot or with shoes resolved by non-linearly scaled wavelets. J Biomech. 2003 Aug;36(8):1169-76. doi: 10.1016/s0021-9290(03)00086-1.

Reference Type BACKGROUND
PMID: 12831743 (View on PubMed)

von Tscharner V, Gopfert B, Wirz D, Friederich NF. [Analysis of wavelet transformed electromyographic signals that were altered by wearing a knee brace]. Biomed Tech (Berl). 2004 Mar;49(3):43-8. doi: 10.1515/BMT.2004.009. German.

Reference Type BACKGROUND
PMID: 15106897 (View on PubMed)

von Tscharner V. Time-frequency and principal-component methods for the analysis of EMGs recorded during a mildly fatiguing exercise on a cycle ergometer. J Electromyogr Kinesiol. 2002 Dec;12(6):479-92. doi: 10.1016/s1050-6411(02)00005-6.

Reference Type BACKGROUND
PMID: 12435545 (View on PubMed)

von Tscharner V. Intensity analysis in time-frequency space of surface myoelectric signals by wavelets of specified resolution. J Electromyogr Kinesiol. 2000 Dec;10(6):433-45. doi: 10.1016/s1050-6411(00)00030-4.

Reference Type BACKGROUND
PMID: 11102846 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

LOB_00001_patella

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.