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The Effect of Cold Storage Solutions on Ischemic Injury in Lung Transplantation

NCT ID: NCT00284726

Last Updated: 2023-09-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Study Classification

INTERVENTIONAL

Study Start Date

2000-12-31

Study Completion Date

2005-09-30

Brief Summary

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The purpose of this study is to compare 2 different cold storage solutions, used to preserve donor lungs for lung transplantation, and their effect on cytokine activation related to ischemic reperfusion injury. Primary endpoint is 30 day survival.

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Detailed Description

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The length of ischemic time in harvesting lung allografts is associated with graft survival. It is further thought that ischemic changes in early post-transplantation bronchoscopic biopsies has a direct correlation with later development of chronic rejection.

Conditions

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Lung Transplant Recipients

Interventions

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Celsior Cold Storage Solution

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Any patient undergoing a lung trasnplant at Johns Hopkins Hospital -

Exclusion Criteria

\-
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Johns Hopkins University

OTHER

Sponsor Role lead

Principal Investigators

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John V. Conte, M.D.

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Other Identifiers

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00-10-25-03

Identifier Type: -

Identifier Source: org_study_id

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