Evaluation of Functional MRI and DTI (Imaging Techniques) in Children With Epilepsy and Focal Brain Lesions

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-02-28

Study Completion Date

2008-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is being done to look at the relationship between brain structure and brain function in patients with epilepsy or focal brain lesions (abnormal areas) that require surgery. This study will look at an imaging technique called magnetic resonance imaging (MRI) for looking at the brain. Specifically, the study will look at functional MRI, which is an imaging technique that can map brain function by taking pictures of the brain as it performs different tasks such as reading, thinking, or moving a body part and diffusion tensor imaging (DTI), which will look at brain structure. These types of imaging may help us learn more about different areas of the brain and how those areas of the brain are used in children with epilepsy. We plan to study 30 children with epilepsy.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Utility of PET-MRI in Surveillance of Paediatric Brain Tumours

NCT05553899

Brain Tumor, Pediatric

RECRUITING NA

Study of Brain Tumors (Tectal Tumors) Using Magnetic Resonance Imaging

NCT00229814

Tectal Plate Glioma

WITHDRAWN

Upright Open MRI for Brain Imaging in Children - a Pilot Study

NCT06257498

Brain Tumor

COMPLETED NA

Improving Surgical Outcomes in Patients With Low Grade Gliomas Using Advanced Pre- and Intra-operative MRI

NCT02884947

Brain Neoplasms

COMPLETED

A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With Gliomas

NCT01117155

Ependymoma Brainstem Glioma Astrocytoma +2 more

WITHDRAWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Epilepsy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Functional MRI, Diffusion Tensor Imaging

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* children with intractable epilepsy

Exclusion Criteria

* children requiring sedation for scanning

Minimum Eligible Age

4 Years

Maximum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Children's Healthcare of Atlanta

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Richard Jones, PhD

Role: PRINCIPAL_INVESTIGATOR

Emory University/Children's Healthcare of Atlanta

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Children's Healthcare of Atlanta at Scottish Rite

Atlanta, Georgia, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Functional MRI

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors

NCT00005083 WITHDRAWN PHASE2

Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma

NCT00005084 UNKNOWN PHASE2

Cognitive Biomarkers in Pediatric Brain Tumor Patients

NCT02914067 RECRUITING NA

Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for Gliomas

NCT00274755 COMPLETED PHASE2

Fast Brain MRI in Children With Suspected Brain Tumor

NCT05776602 RECRUITING

Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors

NCT00870129 RECRUITING NA

Feasibility and Clinically Application of Magnetic Resonance Fingerprinting

NCT02387840 TERMINATED NA

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

NCT00187226 COMPLETED PHASE2

Dose Response of Functionally Critical Brain Regions for Brain Radiotherapy

NCT01212237 WITHDRAWN

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

NCT01106794 RECRUITING

FDOPA-PET/MRI for the Pre-operative Evaluation of Gliomas

NCT02371031 TERMINATED PHASE1

Diffusion Tensor MRI to Distinguish Brain Tumor Recurrence From Radiation Necrosis

NCT00285324 COMPLETED

Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities

NCT00589095 TERMINATED

MRI and Diffusion Imaging of Eloquent Brain Areas to Optimize Brain Tumor Resection Planning

NCT01534104 COMPLETED NA

Evaluation of Kidney Function in Children With Brain Tumors

NCT00229801 WITHDRAWN NA

MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases

NCT04246879 ACTIVE_NOT_RECRUITING NA

Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery

NCT01417507 COMPLETED

A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain Tumors

NCT02006407 TERMINATED NA

Child's Study of the Impact of PF Lesion on Motor Skills, Language, Cognitive Functioning and Social Cognition

NCT04174820 UNKNOWN

Monitoring MRI Changes Before and During Radiotherapy Treatment of Brain Tumors

NCT03394716 TERMINATED

1.5T Intraoperative MR Imaging in Craniopharyngiomas

NCT01206543 COMPLETED NA

Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

NCT07226453 NOT_YET_RECRUITING PHASE2

Evaluation of Human Brain Tumor Therapy Response by Magnetic Resonance (MR)

NCT00724191 COMPLETED

Radiation Induced Alterations in Resting State Brain Networks in Pediatric Brain Tumor Patients

NCT06185686 RECRUITING

A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor

NCT05288439 ACTIVE_NOT_RECRUITING NA