Dispatcher-Assisted Resuscitation Trial (DART)

NCT ID: NCT00219687

Last Updated: 2014-10-29

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE3
• Total Enrollment: 5494 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2004-06-30
• Study Completion Date: 2012-08-31

Brief Summary

The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital cardiac arrests.

Detailed Description

Out-of-hospital cardiac arrest, a condition characterized by a person suddenly collapsing due to heart stoppage, is a leading cause of death in the United States. In out-of-hospital cardiac arrest, survival is dependent upon what the American Heart Association has termed the chain of survival which includes quick activation of the 9-1-1 system, prompt cardiopulmonary resuscitation (CPR), early defibrillation, and qualified advanced life support care (paramedic care). CPR allows for some circulation and delivery of oxygen to vital organs when the heart is no longer beating on its own. However, in some instances, the citizen bystander has not been trained in CPR, presenting a circumstance where the cardiac arrest victim may not receive CPR until the arrival of emergency medical services (EMS) personnel (i.e., paramedics). The delay in CPR adversely affects outcome and dcreases the chance of survival. In response to this need, the EMS Division of Public Health - Seattle and King County developed and instituted telephone CPR instructions that could be provided "on-the-spot" during a cardiac arrest by the emergency medical (9-1-1) dispatcher. The instructions are designed to be given over the phone to persons who have not had previous CPR training so that they can initiate CPR prior to the arrival of EMS personnel and have been termed "dispatcher-assisted" CPR. The dispatcher instructions provided by the dispatch agencies of King County include the standard "full" CPR protocol of ventilations (breathing into the victim's mouth to inflate the lungs) and chest compressions(pumping on the patients chest to help circulate the blood). The ventilations oxygenate the blood while the chest compressions pump the oxygenated blood forward. This EMS program has led to a considerable increase in the proportion of cardiac arrest victims in King County that receive citizen bystander CPR prior to EMS arrival and has been associated with improved survival (appendix 1).

Comparison: Dispatcher-assisted CPR instructions with compressions and ventillations compared to dispatcher-assisted CPR instructions with compressions only.

Conditions

Heart Arrest

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

1

When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions only

Group Type: ACTIVE_COMPARATOR

dispatcher-assisted CPR instructions with compressions only

Intervention Type: OTHER

Delivery of telephone CPR instructions to lay callers with hands-only chest compressions when the patient is identified to be in cardiac arrest

2

When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions and breaths

Group Type: ACTIVE_COMPARATOR

dispatcher-assisted CPR with compressions & ventilations

Intervention Type: OTHER

Delivery of telephone CPR instructions to lay callers with chest compressions and ventilations when the patient is identified to be in cardiac arrest

Interventions

dispatcher-assisted CPR with compressions & ventilations

Delivery of telephone CPR instructions to lay callers with chest compressions and ventilations when the patient is identified to be in cardiac arrest

Intervention Type: OTHER

dispatcher-assisted CPR instructions with compressions only

Delivery of telephone CPR instructions to lay callers with hands-only chest compressions when the patient is identified to be in cardiac arrest

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Cardiac arrest events where CPR is not ongoing but a bystander is willing to attempt with assistance

Exclusion Criteria

• Pregnancy
• Prisoners
• Cardiac arrest due to asphyxia, drowning, hanging, or electrocution

• Minimum Eligible Age: 9 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Public Health - Seattle and King County

OTHER_GOV

Sponsor Role: lead

Responsible Party

Susan Damon

Program Manager

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Thomas D Rea, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

Division of Emergency Medical Services, Public Health - Seattle and King County

Mickey S Eisenberg, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Division of Emergency Medical Services, Public Health - Seattle and King County

Locations

Thurston County Dispatch

Olympia, Washington, United States

Division of Emergency Medical Services, Public Health - Seattle and King County

Seattle, Washington, United States

London Ambulance Service

London, England, United Kingdom

Countries

United States; United Kingdom

References

Rea TD, Fahrenbruch C, Culley L, Donohoe RT, Hambly C, Innes J, Bloomingdale M, Subido C, Romines S, Eisenberg MS. CPR with chest compression alone or with rescue breathing. N Engl J Med. 2010 Jul 29;363(5):423-33. doi: 10.1056/NEJMoa0908993.

Reference Type: DERIVED

PMID: 20818863 (View on PubMed)

Other Identifiers

RARC-0001-01

Identifier Type: -

Identifier Source: org_study_id