The Roles of Tissue Factor in Malignant Gliomas

NCT ID: NCT00201903

Last Updated: 2017-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-01-31

Study Completion Date

2006-10-31

Brief Summary

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To explore the relationship between tissue factor levels, tumour progression, activation of blood coagulation and venous thromboembolism with malignant glioma

Detailed Description

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To explore the relationship between tissue factor levels, tumour progression, activation of blood coagulation and venous thromboembolism with malignant glioma

Conditions

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Venous Thromboembolism Brain Tumors

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* participation in PRODIGE
* adult patients
* newly diagnosed, biopsy-confirmed grade III/IV malignant gliomas
* undergone craniotomy or stereotactic biopsy \> 2 days and \< 4 weeks before

Exclusion Criteria

* have known hereditary thrombophilia
* are receiving experimental antiangiogenic therapy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ontario Cancer Research Network

NETWORK

Sponsor Role collaborator

Ontario Clinical Oncology Group (OCOG)

OTHER

Sponsor Role lead

Principal Investigators

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Agnes Lee, MD

Role: STUDY_CHAIR

Hamilton Health Sciences and McMaster University

William Geerts, MD

Role: PRINCIPAL_INVESTIGATOR

Sunnybrook Health Sciences Centre

Mark Levine, MD

Role: PRINCIPAL_INVESTIGATOR

Ontario Clinical Oncology Group (OCOG)

James Perry, MD

Role: PRINCIPAL_INVESTIGATOR

Toronto Sunnybrook Regional Cancer Centre

Janusz Rak

Role: PRINCIPAL_INVESTIGATOR

Hamilton Health Sciences and McMaster University

Jeffrey Weitz, MD

Role: PRINCIPAL_INVESTIGATOR

Hamilton Health Sciences and McMaster University

Locations

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Henry Ford Hospital

Detroit, Michigan, United States

Site Status

Huntsman Cancer Institute

Salt Lake City, Utah, United States

Site Status

Cross Cancer Institute

Edmonton, Alberta, Canada

Site Status

CancerCare Manitoba

Winnipeg, Manitoba, Canada

Site Status

Toronto-Sunnybrook Regional Cancer Centre

Toronto, Ontario, Canada

Site Status

Princess Margaret Hospital

Toronto, Ontario, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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OCOG-2003-TFsubstudy

Identifier Type: -

Identifier Source: org_study_id

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