Analysis of Cell Count, Viability, and Immunogenicity of Discarded Newly Diagnosed Glioblastoma Tissue or Solid Tumor Tissues

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

141 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-03

Study Completion Date

2025-06-30

Brief Summary

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This study examines tumor tissues and blood samples to aid in the development of therapies for brain cancer and other solid tumors. Studying samples of blood and tissue from patients with glioblastoma or other solid tumor in the laboratory may help doctors understand brain tumors and better inform future treatments.

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Detailed Description

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PRIMARY OBJECTIVES:

I. Assessment of cell yield and percentage of viable cells upon tissue receipt at the cell processing facility.

II. Obtain discarded tumor tissue from surgical resections for further studies to aid in development of future therapies for glioblastoma (GBM) and other solid tumors.

SECONDARY OBJECTIVE:

I. Assessment of cell yield and percentage of viable cells from other solid tumor cells shipped to the cell processing facility.

EXPLORATORY OBJECTIVE:

I. An additional line of inquiry will be devoted to scientific exploration of the product's immunogenicity looking at important variables in the course of manufacture.

OUTLINE:

Patients undergo collection of tissue sample during surgery. Patients also undergo collection of blood sample.

Conditions

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Glioblastoma Malignant Solid Neoplasm

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Basic Science (Biospecimen collection)

Patients undergo collection of tissue sample during surgery. Patients also undergo collection of blood sample.

Biospecimen Collection

Intervention Type PROCEDURE

Undergo collection of tissue and blood samples

Interventions

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Biospecimen Collection

Undergo collection of tissue and blood samples

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Provide signed and dated informed consent form
* Any individual \>= 18 years old
* Patients must have GBM or other solid tumor and undergoing surgery for diagnostic and therapeutic purposes