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Treatment Choices for Improving Adherence and Outcome

NCT ID: NCT00194948

Last Updated: 2013-11-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-09-30

Study Completion Date

2007-05-31

Brief Summary

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This study will determine the effectiveness of offering primary care patients their preferred treatment versus one that is less desirable in improving treatment adherence and outcome.

Detailed Description

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This study investigates whether offering primary care patients treatment that is congruent with their preferred first choice improves adherence and outcomes, in comparison to offering treatment that is not congruent with their preferred first choice. All subjects are offered a treatment with demonstrated efficacy, namely either the antidepressant medication escitalopram or Interpersonal Psychotherapy for 5 months. We hypothesize that patients who receive congruent treatment will be more likely to initiate treatment, adhere to treatment, and achieve depression remission.

Conditions

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Major Depression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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escitalopram

Intervention Type DRUG

interpersonal psychotherapy

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* age 21-99
* English-speaking
* DSM-IV criteria for major depression

Exclusion Criteria

* unable to give informed consent
* MMSE\<24
* DSM-IV diagnosis of bipolar disorder, psychotic disorder, current alcohol or substance abuse
* active suicide ideation
* aphasia
* acute or severe medical illness
* currently receiving either antidepressant medication or psychotherapy
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role collaborator

Weill Medical College of Cornell University

OTHER

Sponsor Role lead

Principal Investigators

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Patrick J Raue, PhD

Role: PRINCIPAL_INVESTIGATOR

Weill Medical College of Cornell University

Locations

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Cornell Internal Medicine Associates

New York, New York, United States

Site Status

Weill Medical College of Cornell University

White Plains, New York, United States

Site Status

Countries

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United States

Other Identifiers

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K23MH069784

Identifier Type: NIH

Identifier Source: secondary_id

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DSIR 8K-RTSE

Identifier Type: -

Identifier Source: secondary_id

K23MH069784

Identifier Type: NIH

Identifier Source: org_study_id

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