Radiation Dosimetry in Teeth

NCT ID: NCT00178347

Last Updated: 2009-05-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-12-31

Brief Summary

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Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).

It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.

Detailed Description

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Conditions

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Radiation Tolerance

Study Design

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Study Time Perspective

RETROSPECTIVE

Interventions

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Exposure to irradiation

Treatment for Cancer using Radiation -dose will be the standard of Care for the type of Cancer being treated

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Discarded pathologic specimens (teeth)
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Rochester

OTHER

Sponsor Role lead

Responsible Party

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University of Rochester, Medical Center

Principal Investigators

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Paul Okunieff, MD

Role: STUDY_CHAIR

University of Rochester, Dept. of Radiation Oncology

Locations

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University of Rochester, Dept. Radiation Oncology

Rochester, New York, United States

Site Status

Countries

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United States

Other Identifiers

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URCC 11070

Identifier Type: -

Identifier Source: org_study_id

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