Circulating Cytokines as Predictors of Radiation Induced Pulmonary Toxicity

NCT ID: NCT00178230

Last Updated: 2017-06-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

82 participants

Study Classification

OBSERVATIONAL

Study Start Date

1996-03-15

Study Completion Date

2013-11-25

Brief Summary

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This study is being conducted by the University of Rochester Cancer Center to determine the levels of cytokines in the blood, and to determine if blood levels of these cytokines are related to the side effects of radiation therapy combined with other treatments.

Detailed Description

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Conditions

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Lung Neoplasms

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

Patients receiving radiation therapy for lung cancer combined with surgery either pre or post RT to the chest for lung cancer not associated with atelectasis, pleural effusion.

Patients receiving HDR Brachytherapy for lung cancer.

Patients receiving concomitant radiation and interferon therapy for lung cancer.

Patients receiving concomitant chemotherapy and radiation for lung cancer. Prior drug therapy does not make patients ineligible.

Karnofsky ≥ 70 %.

There are no age restrictions.

Acceptable bone marrow function - WBC 2 3000/mm3, platelet count \> 100,000, hematocrit ≥ 33%, hemoglobin ≥ 11 gms/dl.

Life expectancy \> 6 months.

Patients must sign informed consent meeting all federal and institutional guidelines.

Exclusion Criteria

Patients not meeting eligibility criteria stated above
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Rochester

OTHER

Sponsor Role lead

Responsible Party

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Yuhchyau Chen

Proffessor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yuhchyau Chen, MD, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Universtiy of Rochester, Dept of Radiation Oncology

Locations

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University of Rochester, Dept. Radiation Oncology

Rochester, New York, United States

Site Status

Countries

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United States

Other Identifiers

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URCC 4595

Identifier Type: -

Identifier Source: org_study_id

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