Magnetic Resonance Imaging in Subjects With Gouty Tophi

NCT ID: NCT00174954

Last Updated: 2010-07-27

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-03-31

Study Completion Date

2003-01-31

Brief Summary

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The purpose of this study is to determine the reproducibility of Magnetic Resonance Imaging (MRI) in the quantitative assessment of tophus volume.

Detailed Description

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This is a multi-center, validation study of MRI in the quantitative assessment of gouty tophi. Subjects with palpable gouty tophi (confirmed by aspiration of the tophus) in select anatomical sites (foot, hand or elbow) will undergo pre- and post contrast MRI on two occasions separated by 5 to 10 days. This study will consist of up to 4 study visits.

Conditions

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Hyperuricemia Gout

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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1

Volumes/measurements of tophi determined by serial MRIs

MRI

Intervention Type PROCEDURE

Subjects underwent MRI to evaluate tophi.

Interventions

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MRI

Subjects underwent MRI to evaluate tophi.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Subjects with gout and at least one tophi.

Exclusion Criteria

* Unable to undergo MRI.
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Takeda

INDUSTRY

Sponsor Role lead

Responsible Party

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Takeda Global Research & Development Center, Inc.

Principal Investigators

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Medical Director

Role: STUDY_CHAIR

Takeda

References

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Schumacher HR Jr, Becker MA, Edwards NL, Palmer WE, MacDonald PA, Palo W, Joseph-Ridge N. Magnetic resonance imaging in the quantitative assessment of gouty tophi. Int J Clin Pract. 2006 Apr;60(4):408-14. doi: 10.1111/j.1368-5031.2006.00853.x.

Reference Type RESULT
PMID: 16620352 (View on PubMed)

Related Links

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Other Identifiers

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U1111-1113-9856

Identifier Type: REGISTRY

Identifier Source: secondary_id

TMX-01-013

Identifier Type: -

Identifier Source: org_study_id

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