Internet-Based Nutrition Education Program in Preventing Cancer in Participants of Health Maintenance Organizations

NCT ID: NCT00169312

Last Updated: 2013-09-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

2619 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-08-31

Study Completion Date

2007-06-30

Brief Summary

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RATIONALE: Websites for nutrition education may be an effective method to help people eat more fruits and vegetables which may lower their risk of cancer.

PURPOSE: This randomized trial is studying how well an internet-based nutrition education program works in preventing cancer in participants of health maintenance organizations.

Detailed Description

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OBJECTIVES:

Primary

* Compare the effects of internet-based nutrition education through untailored websites vs tailored websites (TW) vs TW and tailored human online behavioral interaction (HOBI) on the change in the number of daily fruit and vegetable servings consumed in participants of health maintenance organizations.

Secondary

* Compare the proportion of participants reporting consumption of 5 or more servings of fruits and vegetables per day at each 3-month interval.
* Compare the change in fruit and vegetable servings consumed from baseline to each intermediate time point.
* Compare the effects of intervention and observation time in these participants.
* Determine the effect of HOBI in these participants.
* Compare the impact of participant characteristics, in terms of the effect of the intervention on the change in fruit and vegetable intake, in these participants.

OUTLINE: This is a randomized, controlled, single-blind, multicenter study. Participants are stratified according to participating site, gender, and the participant's stage of change readiness. Participants are randomized to 1 of 3 intervention arms.

* Arm I (untailored websites): Participants are given unlimited access to an internet-based nutrition education program for up to 6 months. They are provided with 4 serial educational websites at 1, 3, 13, and 15 weeks after initial login. These internet sites provide general information about fruits and vegetables, new recipes with emphasis on fruits and vegetables, and how participants can incorporate them into their diet. Participants complete an online survey at 3 months.
* Arm II (tailored websites): Participants are given unlimited access to an internet-based nutrition education program for up to 6 months. They are provided with 4 serial educational websites, at the same timepoints as in arm I, with emphasis on vegetable consumption in weeks 1 and 13 and fruit consumption in weeks 3 and 15. Materials in these websites, including new recipes with emphasis on fruits and vegetables, are tailored and then revised (or retailored) based on individual health-risk information obtained at baseline and at the 3-month online survey.
* Arm III (tailored websites and human online behavioral interaction \[HOBI\]): Participants are given unlimited access to an internet-based nutrition education program for up to 6 months. Participants are provided with 4 serial educational websites with tailored materials as in arm II. They also receive HOBI (tailored e-mail messages) developed and then revised based on health-risk information obtained at baseline and the 3-month online survey.

In all arms, participants complete online surveys at 3, 6, and 12 months to measure fruit and vegetable intake and change in long-term risk behavior. For each survey, participants receive up to 6 automatically generated reminder e-mails and 1 mailed announcement.

PROJECTED ACCRUAL: A total of 2,619 participants were accrued for this study.

Conditions

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Unspecified Adult Solid Tumor, Protocol Specific

Keywords

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unspecified adult solid tumor, protocol specific

Study Design

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Allocation Method

RANDOMIZED

Blinding Strategy

SINGLE

Interventions

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behavioral dietary intervention

Intervention Type BEHAVIORAL

dietary intervention

Intervention Type DIETARY_SUPPLEMENT

educational intervention

Intervention Type OTHER

internet-based intervention

Intervention Type OTHER

preventative dietary intervention

Intervention Type OTHER

evaluation of cancer risk factors

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

DISEASE CHARACTERISTICS:

* Current member of any of the following participating health maintenance organizations:

* Group Health Cooperative
* Kaiser Permanente, Colorado
* Kaiser Permanante, Georgia
* HealthPartners Research Foundation
* Henry Ford Health System/Health Alliance Plan
* Must complete a web-based health survey prior to randomization

PATIENT CHARACTERISTICS:

* No medical or mental health condition that would be adversely affected by increased vegetable and fruit intake
* One participant allowed per household

PRIOR CONCURRENT THERAPY:

* No concurrent anticoagulation therapy (e.g., warfarin)
* No other concurrent medications that would be adversely affected by increased vegetable and fruit intake
* No grapefruit concurrently with any of the following medications:

* Statin for high cholesterol
* Blood pressure medications (e.g., Losartan)
* Calcium channel blockers
* Certain psychiatric medications (e.g., buspirone hydrochloride, triazolam \[Halcion\], carbamazepine, diazepam \[Valium\], or midazolam hydrochloride)
* Immune suppressants (e.g., cyclosporine or tacrolimus)
* Impotence medications (e.g., sildenafil \[Viagra\])
* Methadone
Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Josephine Ford Cancer Center

OTHER

Sponsor Role lead

Principal Investigators

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Christine Cole Johnson, PhD

Role: PRINCIPAL_INVESTIGATOR

Josephine Ford Cancer Center

Locations

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Kaiser Permanente - Colorado

Denver, Colorado, United States

Site Status

Kaiser Permanente, Georgia

Atlanta, Georgia, United States

Site Status

HealthPartners Research Foundation

Minneapolis, Minnesota, United States

Site Status

Group Health Cooperative

Seattle, Washington, United States

Site Status

Countries

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United States

References

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Stopponi MA, Alexander GL, McClure JB, Carroll NM, Divine GW, Calvi JH, Rolnick SJ, Strecher VJ, Johnson CC, Ritzwoller DP. Recruitment to a randomized web-based nutritional intervention trial: characteristics of participants compared to non-participants. J Med Internet Res. 2009 Aug 26;11(3):e38. doi: 10.2196/jmir.1086.

Reference Type BACKGROUND
PMID: 19709990 (View on PubMed)

Couper MP, Alexander GL, Zhang N, Little RJ, Maddy N, Nowak MA, McClure JB, Calvi JJ, Rolnick SJ, Stopponi MA, Cole Johnson C. Engagement and retention: measuring breadth and depth of participant use of an online intervention. J Med Internet Res. 2010 Nov 18;12(4):e52. doi: 10.2196/jmir.1430.

Reference Type DERIVED
PMID: 21087922 (View on PubMed)

Other Identifiers

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HFH-B40389

Identifier Type: -

Identifier Source: secondary_id

CDR0000514226

Identifier Type: -

Identifier Source: org_study_id