Multiepitope Peptide Vaccination in Melanoma

NCT ID: NCT00153569

Last Updated: 2010-05-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-03-31

Study Completion Date

2005-09-30

Brief Summary

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This trial assesses the clinical efficacy of a multiepitope peptide vaccine with GM-CSF and KLH as immunological adjuvants in stage IV melanoma patients

Detailed Description

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Conditions

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Metastatic Melanoma

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Tyrosinase, MAGE-3, GnTV

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Metastatic melanoma
* HLA-A1, -A2, -A24, -B44
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Principal Investigators

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Ulrich Keilholz, MD

Role: PRINCIPAL_INVESTIGATOR

Charité, CBF

Locations

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Hem&Onc Charité CBF

Berlin, , Germany

Site Status

Countries

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Germany

References

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Scheibenbogen C, Schadendorf D, Bechrakis NE, Nagorsen D, Hofmann U, Servetopoulou F, Letsch A, Philipp A, Foerster MH, Schmittel A, Thiel E, Keilholz U. Effects of granulocyte-macrophage colony-stimulating factor and foreign helper protein as immunologic adjuvants on the T-cell response to vaccination with tyrosinase peptides. Int J Cancer. 2003 Mar 20;104(2):188-94. doi: 10.1002/ijc.10961.

Reference Type BACKGROUND
PMID: 12569574 (View on PubMed)

Other Identifiers

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HaemaCBFMM03

Identifier Type: -

Identifier Source: org_study_id

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