Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-12-31

Brief Summary

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Prevalence of chronic pain after mastectomy is beyond 50% 3 months after surgery. This pain is related to a sensitization of the central nervous system through N-methyl-D-asparate (NMDA) receptors. Ketalar might prevent the occurrence of chronic pain by anti-NMDA properties after mastectomy.

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Detailed Description

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Conditions

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Pain Breast Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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ketalar

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Mastectomy in patients 18 to 80 years old

Exclusion Criteria

* American Society of Anesthesiology (ASA) class \>= 3
* Renal, heart or hepatic failure
* Allergy to ketalar
* Psychiatric disease
* Chronic antalgic treatment

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No