KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-01-31

Study Completion Date

2005-05-31

Brief Summary

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We assessed the effects of the N Methyl aspartate receptor antagonist Ketamine on long-term post thoracotomy pain. We hypothesized that ketamine could prevent supersensitization of the central nervous system involved in this chronic neuropathic pain.

Detailed Description

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In this clinical, randomized prospective study, peri operative administration of ketamine was compared to placebo on long term post thoracotomy pain after a 2 months follow up period.

Conditions

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Ketamine Chronic Post Thoracotomy Pain Thoracotomy Pain Neuralgia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Ketamine (or placebo : isotonic saline solution)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients eligible for thoracotomy or pneumectomy

Exclusion Criteria

\-

Minimum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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Thierry GUENOUN, MD

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Locations

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Georges Pompidou European Hospital

Paris, Île-de-France Region, France

Site Status

Countries

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France

References

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Frappier J, Guenoun T, Journois D, Philippe H, Aka E, Cadi P, Silleran-Chassany J, Safran D. Airway management using the intubating laryngeal mask airway for the morbidly obese patient. Anesth Analg. 2003 May;96(5):1510-1515. doi: 10.1213/01.ANE.0000057003.91393.3C.

Reference Type BACKGROUND

PMID: 12707159 (View on PubMed)

Other Identifiers

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CRC99029

Identifier Type: -

Identifier Source: secondary_id

P990911