Effects of Epinephrine and Intravenous (I.V.) Needle on Cardiopulmonary Resuscitation (CPR) Outcome
NCT ID: NCT00121524
Last Updated: 2015-05-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE2
904 participants
INTERVENTIONAL
2003-01-31
2008-06-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
NCT03921346
Sensitivity of ECG on Detection of Three Different Intravascular Applied Test Doses of Bupivacaine and Epinephrine
NCT01091766
Reducing Medication Errors and Time to Drugs Delivery During Pediatric Cardiopulmonary Resuscitation: a Multicenter RCT
NCT03021122
DEpth of EPinephrine Delivery With Auto-injectors Devices
NCT02886468
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest
NCT04624776
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
IV yes
Intravenous needle Epinephrine q 3 min during CPR Atropine 3 mg in initial asystole Amiodarone 300 mg iv after repeated failed defibrillation attempts
Epinephrine
Epinephrine 1 mg is given iv. every 3 min during CPR
Intravenous needle
An intravenous needle in placed as soon as possible during CPR
Atropine
Atropine 3 mg iv in initial systole
Amiodarone
amiodarone 300 mg iv after repeated failed defibrillation attempts
IV no
The patient will not have an intravenous needle placed or given any drugs during CPR. If patient obtains spontaneous circulation, an intravenous needle is placed and patient can receive any drugs that are appropriate during the following treatment.
No interventions assigned to this group
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Epinephrine
Epinephrine 1 mg is given iv. every 3 min during CPR
Intravenous needle
An intravenous needle in placed as soon as possible during CPR
Atropine
Atropine 3 mg iv in initial systole
Amiodarone
amiodarone 300 mg iv after repeated failed defibrillation attempts
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Trauma as cause of arrest
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Laerdal Medical
INDUSTRY
Ullevaal University Hospital
OTHER
Health Region East, Norway
OTHER
Norwegian Air Ambulance Foundation
OTHER
University of Oslo
OTHER
Petter Andreas Steen
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Petter Andreas Steen
Professor Acute Medicine
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Lars Wik, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Ullevaal University Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Ulleval University Hospital
Oslo, , Norway
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Holmberg M, Holmberg S, Herlitz J. Low chance of survival among patients requiring adrenaline (epinephrine) or intubation after out-of-hospital cardiac arrest in Sweden. Resuscitation. 2002 Jul;54(1):37-45. doi: 10.1016/s0300-9572(02)00048-5.
Olasveengen TM, Sunde K, Brunborg C, Thowsen J, Steen PA, Wik L. Intravenous drug administration during out-of-hospital cardiac arrest: a randomized trial. JAMA. 2009 Nov 25;302(20):2222-9. doi: 10.1001/jama.2009.1729.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
525-02201
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.