Pain Control in Patients With Recurrent or Metastatic Breast or Prostate Cancer

NCT ID: NCT00002668

Last Updated: 2023-06-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

1996-02-14

Study Completion Date

1998-09-30

Brief Summary

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RATIONALE: An outpatient educational and behavioral skills training program may help patients with metastatic breast or prostate cancer live longer and more comfortably.

PURPOSE: This randomized clinical trial studies whether an outpatient educational and behavioral skills training program will improve pain control in patients who have metastatic or recurrent breast or prostate cancer.

Detailed Description

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OBJECTIVES:

* Evaluate the feasibility of implementing an outpatient education and behavioral skills training program for pain control in a multi-institution setting.
* Evaluate whether patient education and behavioral skills training improve cancer pain control in patients with recurrent or metastatic breast or prostate cancer.
* Amend the protocol, with the approval of the Division of Cancer Prevention and Control, to a groupwide 3-arm study if analysis demonstrates feasibility and potential efficacy of the patient education and behavioral skills training program.

OUTLINE: This is a randomized study. Patients are stratified according to diagnosis (breast vs prostate cancer), initial "pain worst" score (4-6 vs 7 or higher), and participating institution. Patients are randomized to 1 of 2 treatment arms.

* Arm I: Patients receive standard pain management.
* Arm II: Patients receive educational intervention (booklets, audiotapes, and videotapes) and behavioral skills training (including a schedule of practice relaxation sessions) in addition to standard pain management. Patients receive a follow-up phone call within 48-72 hours of intervention to review pain status.

Patients on both arms undergo pain and psychological assessments on days 1 and 15.

PROJECTED ACCRUAL: A total of 96 patients (48 per arm) will be accrued for this study.

Conditions

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Breast Cancer Pain Prostate Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Observation

Standard pain management interventions usually given by hospital staff

Group Type ACTIVE_COMPARATOR

Observation

Intervention Type BEHAVIORAL

Educational Intervention and Behavioral Skills Training

Patients participated in a program including video presentations, written materials, and coaching in behavioral skills to improve pain control (not to reduce analgesic use).

Group Type EXPERIMENTAL

Educational Intervention and Behavioral Skills Training

Intervention Type BEHAVIORAL

Interventions

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Observation

Intervention Type BEHAVIORAL

Educational Intervention and Behavioral Skills Training

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Hormone receptor status:

* Not specified

PATIENT CHARACTERISTICS:

Age:

* 18 and over

Menopausal status:

* Not specified

Performance status:

* ECOG 0-2

Hematopoietic:

* Not specified

Hepatic:

* Not specified

Renal:

* Not specified

Other:

* No major psychiatric illness, including the following DSM-III-R diagnoses:

* Bipolar disorder
* Schizophrenia
* Major depression
* Multiple personality disorder
* Psychotic disorder
* Dementia
* Outpatient status required

PRIOR CONCURRENT THERAPY:

Biologic therapy:

* Not specified

Chemotherapy:

* Not specified

Endocrine therapy:

* Not specified

Radiotherapy:

* At least 28 days since prior palliative radiotherapy to major site(s) of pain

Surgery:

* Greater than 30 days since prior surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Eastern Cooperative Oncology Group

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Charles Cleeland, PhD

Role: STUDY_CHAIR

M.D. Anderson Cancer Center

Locations

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CCOP - Carle Cancer Center

Urbana, Illinois, United States

Site Status

CCOP - Cedar Rapids Oncology Project

Cedar Rapids, Iowa, United States

Site Status

CCOP - Iowa Oncology Research Association

Des Moines, Iowa, United States

Site Status

John Stoddard Cancer Center at Iowa Methodist Medical Center

Des Moines, Iowa, United States

Site Status

Mercy Cancer Center at Mercy Medical Center-Des Moines

Des Moines, Iowa, United States

Site Status

Iowa Lutheran Hospital

Des Moines, Iowa, United States

Site Status

CCOP - Ochsner

New Orleans, Louisiana, United States

Site Status

CCOP - Metro-Minnesota

Saint Louis Park, Minnesota, United States

Site Status

Midlands Cancer Center at Midlands Community Hospital

Papillion, Nebraska, United States

Site Status

CCOP - Northern New Jersey

Hackensack, New Jersey, United States

Site Status

MBCCOP - University of New Mexico HSC

Albuquerque, New Mexico, United States

Site Status

Penn State Cancer Institute at Milton S. Hershey Medical Center

Hershey, Pennsylvania, United States

Site Status

CCOP - MainLine Health

Wynnewood, Pennsylvania, United States

Site Status

CCOP - Sioux Community Cancer Consortium

Sioux Falls, South Dakota, United States

Site Status

CCOP - St. Vincent Hospital Cancer Center, Green Bay

Green Bay, Wisconsin, United States

Site Status

Westmead Hospital

Westmead, New South Wales, Australia

Site Status

Instituto de Enfermedades Neoplasicas

Lima, , Peru

Site Status

San Juan City Hospital

San Juan, , Puerto Rico

Site Status

Countries

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United States Australia Peru Puerto Rico

Other Identifiers

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U10CA021115

Identifier Type: NIH

Identifier Source: secondary_id

View Link

ECOG-3Z93

Identifier Type: -

Identifier Source: secondary_id

NCI-P95-0068

Identifier Type: -

Identifier Source: secondary_id

CDR0000064257

Identifier Type: -

Identifier Source: org_study_id

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