Combining Behavioral Treatment With Agonist Maintenance - 1

NCT ID: NCT00000311

Last Updated: 2018-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

168 participants

Study Classification

INTERVENTIONAL

Study Start Date

1995-02-28

Study Completion Date

1999-02-28

Brief Summary

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The purpose of this study is to evaluate whether the community reinforcement approach (CRA) plus contingency management (CM) is more effective overall than CRA only in reducing illicit opioid and cocaine use during agonist maintenance treatment and at 3 and 6 month follow-up after completion of study protocol, and to compare the efficacy of maintenance on buprenorphine to methadone when maintenance is combined with CRA only or CRA plus CM.

Detailed Description

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Conditions

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Cocaine-Related Disorders Opioid-Related Disorders Substance-Related Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Study Groups

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1

Methadone + CM (contingency management)

Group Type EXPERIMENTAL

methadone

Intervention Type DRUG

medication and behavioral

2

methadone + VC (voucher control)

Group Type EXPERIMENTAL

methadone

Intervention Type DRUG

medication and behavioral

3

Buprenorphine + CM

Group Type EXPERIMENTAL

Buprenorphine

Intervention Type DRUG

Medication and Behavioral

4

Buprenorphine + VC

Group Type EXPERIMENTAL

Buprenorphine

Intervention Type DRUG

Medication and Behavioral

Interventions

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Buprenorphine

Medication and Behavioral

Intervention Type DRUG

methadone

medication and behavioral

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

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Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

Yale University

OTHER

Sponsor Role lead

Responsible Party

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Yale University School of Medicine

Principal Investigators

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Richard Schottenfeld, M.D.

Role: PRINCIPAL_INVESTIGATOR

Yale University

Locations

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APT Residential Services Division

New Haven, Connecticut, United States

Site Status

Countries

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United States

Other Identifiers

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R01DA009413

Identifier Type: NIH

Identifier Source: secondary_id

View Link

R01-09413-1

Identifier Type: -

Identifier Source: secondary_id

NIDA-09413-1

Identifier Type: -

Identifier Source: org_study_id

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