Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2

NCT ID: NCT00000310

Last Updated: 2017-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE2

Study Classification

INTERVENTIONAL

Study Start Date

1996-01-31

Study Completion Date

1996-03-31

Brief Summary

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The purpose of this study is to evaluate use of risperidone with cocaine abusers. Study measures incorporate an appropriate integration of behavioral and neurobiological indices.

Detailed Description

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Risperidone in low doses is compared with placebo in a 6-week randomized trial. Subjects also receive supportive counseling. Outcome measure include rating of behavior, mood, drug abuse, global function, and urine toxicology.

Conditions

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Cocaine-Related Disorders

Study Design

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Allocation Method

RANDOMIZED

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Risperidone

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Cocaine abuse or dependence

Exclusion Criteria

Dependence on other drugs. Major psychiatric illness
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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VA Boston Healthcare System

FED

Sponsor Role collaborator

National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role lead

Principal Investigators

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Lawrence Price, M.D.

Role: PRINCIPAL_INVESTIGATOR

Brown University

Locations

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Brown University School of Medicine

Providence, Rhode Island, United States

Site Status

Countries

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United States

Other Identifiers

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R01-09330-2

Identifier Type: -

Identifier Source: secondary_id

NIDA-09330-2

Identifier Type: -

Identifier Source: org_study_id

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