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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06924606 | RECRUITING | PHASE2
66 Participants

Evaluating the Preliminary Efficacy and Safety of JS207 in NSCLC After Progression Following Platinum-based Chemotherapy and Immunotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-07-15
Completion: 2026-06-26
Conditions
Advanced NSCLC
Interventions
DRUG
No Results Yet
NCT06910215 | COMPLETED | NA
195 Participants

Effect of Elastic Therapeutic Taping on Post-Sternotomy Pain in Coronary Artery Bypass Graft Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-01-22
Completion: 2025-12-24
Conditions
Postoperative Pain Sternotomy Pain Management Coronary Artery Bypass
Interventions
OTHER
No Results Yet
NCT06908954 | RECRUITING | PHASE1
32 Participants

A Study of the Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-03-14
Completion: 2026-06-17
Conditions
Hepatic Impairment Healthy
Interventions
DRUG
No Results Yet
NCT06900179 | ENROLLING_BY_INVITATION | NA
188 Participants

The Effectiveness of Augmented Reality Facilitated Education in Promoting Care Management of Malignant Fungating Wounds Among Oncology Nurses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-01
Completion: 2025-03-12
Conditions
Nursing Education
Interventions
OTHER
No Results Yet
NCT06880250 | ENROLLING_BY_INVITATION
100 Participants

Efficacy and Safety of Enzyme Replacement Therapy in Patients With Fabry Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-03-24
Completion: 2027-01-31
Conditions
Fabry Disease
No Results Yet
NCT06877949 | RECRUITING | NA
420 Participants

FDG-PET/CT vs. CT for Monitoring Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-04-02
Completion: 2029-04-30
Conditions
Metastatic Breast Cancer Response Monitoring
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06860971 | RECRUITING | PHASE3
144 Participants

A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-04-18
Completion: 2027-01-31
Conditions
Thyroid Cancer
Interventions
DRUG
No Results Yet
NCT06858878 | ACTIVE_NOT_RECRUITING | PHASE3
1105 Participants

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-03-17
Completion: 2027-01-21
Conditions
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Interventions
DRUG
No Results Yet
NCT06858501 | NOT_YET_RECRUITING | PHASE2
84 Participants

Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-03-22
Completion: 2028-12-20
Conditions
Ganglioneuroblastoma Ganglioneuroblastoma, Nodular High Risk Neuroblastoma
Interventions
PROCEDURE RADIATION OTHER
No Results Yet
NCT06857955 | RECRUITING | PHASE2
380 Participants

A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-03-26
Completion: 2026-12-31
Conditions
Hypertension
Interventions
OTHER DRUG
No Results Yet
NCT06855277 | RECRUITING | PHASE3
940 Participants

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-07-01
Completion: 2028-02-29
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06850038 | RECRUITING
30 Participants

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-04-22
Completion: 2029-11-30
Conditions
Alagille Syndrome
No Results Yet
NCT06846931 | COMPLETED | NA
90 Participants

Comparison of the Efficacy of Shock Wave Therapy and Laser Therapy for Plantar Fasciitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-03-07
Completion: 2025-12-25
Conditions
Plantar Fasciitis, Chronic
Interventions
OTHER
No Results Yet
NCT06805331 | COMPLETED | NA
46 Participants

The Effect of Health Belief Model-Based Pelvic Floor Muscle Exercise Training on Urinary Incontinence and Quality of Life in Female Patients With Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-04-09
Completion: 2025-06-01
Conditions
Multiple Sclerosis Urinary Incontinence
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06783413 | COMPLETED | NA
40 Participants

Effects of Laughter Yoga on Fatigue, Sleep Quality and Psychological Well-Being in Patients With Multiple Sclerosis: A Randomized Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-04-15
Completion: 2025-05-30
Conditions
Multiple Sclerosis Fatigue Sleep Quality Psychological Well-being
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06782581 | RECRUITING | NA
186 Participants

CARE Study: Cancer, Asian Americans, and Relationship Enrichment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-06
Completion: 2027-01-15
Conditions
Neoplasm
Interventions
BEHAVIORAL
No Results Yet
NCT06779630 | RECRUITING | NA
150 Participants

Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions (BIOFLOW-48) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-07-18
Completion: 2027-09-30
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
NCT06770738 | COMPLETED
320 Participants

EuroSCORE-II and POSPOM in Cardiac Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-01-03
Completion: 2025-10-15
Conditions
Cardiac Disease Cardiovascular Diseases Cardiovascular Complication Anesthesia Perioperative/Postoperative Complications Surgery
Interventions
OTHER
No Results Yet
NCT06767150 | RECRUITING | PHASE4
200 Participants

StrAtegies For Zoledronic Acid Post-dEnosumab Discontinuation in Postmenopausal oSTeoporosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-10-02
Completion: 2030-10-31
Conditions
Postmenopausal Osteoporosis
Interventions
DRUG
No Results Yet
NCT06762717 | RECRUITING
500 Participants

FARAPULSE™ Pulsed Field Ablation System

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-10-23
Completion: 2027-12-31
Conditions
Paroxysmal AF
Interventions
DEVICE
No Results Yet
NCT06744166 | COMPLETED | NA
156 Participants

Effect of Transcutaneous Electrical Nerve Stimulation Based on Wrist-ankle Acupuncture Theory on Postoperative Pain After Video-assisted Thoracoscopic Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-02-06
Completion: 2025-06-20
Conditions
Postoperative Pain Video-assisted Thoracoscopic Surgery (VATS)
Interventions
DEVICE
No Results Yet
NCT06738394 | RECRUITING | NA
30 Participants

Enhancing Physical Function in Older Adults With Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-07-31
Completion: 2026-07-31
Conditions
Chronic Kidney Diseases
Interventions
BEHAVIORAL
No Results Yet
NCT06730061 | RECRUITING | PHASE3
18 Participants

A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-01-16
Completion: 2026-03-19
Conditions
Primary Biliary Cholangitis
Interventions
DRUG
No Results Yet
NCT06727604 | RECRUITING | PHASE2
240 Participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-17
Completion: 2028-06-30
Conditions
Graves' Disease
Interventions
DRUG
No Results Yet
NCT06726876 | RECRUITING | PHASE3
150 Participants

Therapeutic Effect of Manuka Honey Oral Rinse in Periodontitis Patients Undergoing Hemodialysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-01
Completion: 2025-12-30
Conditions
Periodontitis Hemodialysis
Interventions
DIETARY_SUPPLEMENT DRUG
No Results Yet
NCT06715839 | RECRUITING | NA
400 Participants

Target-specific immunoPET Imaging of Digestive System Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-04
Completion: 2027-09-30
Conditions
Malignancy Digestive Cancer Digestive System Neoplasm Digestive System Carcinoma Digestive System Cancer Liver Cancer Stomach Cancer Colon Cancer Rectum Cancer Pancreatic Cancer Esophagus Cancer Gallbladder Carcinoma Small Intestine Cancer Appendix Cancer Bile Duct Carcinoma
Interventions
DRUG
No Results Yet
NCT06715397 | ENROLLING_BY_INVITATION
150 Participants

Cross-Cultural Adaptation, Validity and Reliability of the Turkish Version of the Adolfsson-Björnsson Upper Extremity Activity Scale (ABAS)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-12-29
Completion: 2026-10-30
Conditions
Upper Extremity Injuries Questionnaire and Survey Reliability and Validity
Interventions
OTHER
No Results Yet
NCT06714591 | RECRUITING | PHASE1
120 Participants

Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-19
Completion: 2026-12-31
Conditions
Relapsed/Refractory Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT06713434 | ACTIVE_NOT_RECRUITING | PHASE1
20 Participants

Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-05-07
Completion: 2026-06-30
Conditions
Junctional Epidermolysis Bullosa Epidermolysis Bullosa (EB) Dystrophic Epidermolysis Bullosa Recessive Dystrophic Epidermolysis Bullosa
Interventions
BIOLOGICAL
No Results Yet
NCT06712784 | RECRUITING | NA
10 Participants

Behavior Analytic Support of Needle-related Hospital Visits for Autistic Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-01-31
Completion: 2027-03-31
Conditions
Autism Spectrum Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06710119 | RECRUITING | NA
60 Participants

Effect of Custom Dynamic Orthoses on Forefoot Loading

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-06-18
Completion: 2027-12-31
Conditions
Lower Extremity Injuries
Interventions
OTHER
No Results Yet
NCT06706505 | COMPLETED | NA
44 Participants

Mindfulness-Based Art Therapy for Nurses: Difficulties in Emotion Regulation, Burnout, and Psychological Flexibility

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-01
Completion: 2024-12-05
Conditions
Mental Health Wellness 1 Burnout, Professional
Interventions
BEHAVIORAL
No Results Yet
NCT06703073 | RECRUITING | PHASE2
600 Participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-06-10
Completion: 2028-07-31
Conditions
Acute Respiratory Distress Syndrome (ARDS) ARDS ARDS (Acute Respiratory Distress Syndrome) Acute Respiratory Distress Syndrome
Interventions
DRUG
No Results Yet
NCT06701682 | RECRUITING | PHASE2
200 Participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-06-21
Completion: 2028-07-31
Conditions
Acute Respiratory Distress Syndrome (ARDS) ARDS ARDS (Acute Respiratory Distress Syndrome) Acute Respiratory Distress Syndrome
Interventions
DRUG
No Results Yet
NCT06701669 | RECRUITING | PHASE2
200 Participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-06-10
Completion: 2028-07-31
Conditions
Acute Respiratory Distress Syndrome (ARDS) ARDS ARDS (Acute Respiratory Distress Syndrome) Acute Respiratory Distress Syndrome
Interventions
DRUG
No Results Yet
NCT06701656 | RECRUITING | PHASE2
200 Participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-10-28
Completion: 2028-07-31
Conditions
Acute Respiratory Distress Syndrome (ARDS) ARDS ARDS (Acute Respiratory Distress Syndrome) Acute Respiratory Distress Syndrome
Interventions
DRUG
No Results Yet
NCT06699030 | RECRUITING | NA
100 Participants

A Strategy for Gallstone Expulsion Through Dietary Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-24
Completion: 2026-12-01
Conditions
Gallbladder Stone
Interventions
DRUG OTHER
No Results Yet
NCT06697405 | COMPLETED
1444 Participants

Impact of Cardiopulmonary Bypass Time on Gastrointestinal Complications

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-24
Completion: 2025-12-25
Conditions
Valvular Disease
Interventions
OTHER
No Results Yet
NCT06695533 | ACTIVE_NOT_RECRUITING | NA
25 Participants

I Can Do This! Managing My Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2025-08-21
Completion: 2026-01-31
Conditions
Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT06685406 | COMPLETED
120 Participants

The Validity of Thorathic Fluid Content as Non Invasive Predictor on Weaning of Mechanical Ventilation in Critically Ill Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2024-11-18
Completion: 2025-11-18
Conditions
Cardiometry Thorathic Fluid Content Weaning From Mechanical Ventilation
Interventions
DIAGNOSTIC_TEST
No Results Yet
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