Clinical Trials

Showing trials with last updates posted in 2025.

NCT05955326 | RECRUITING | PHASE4
160 Participants

Study to Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-01-08
Completion: 2026-02-28
Conditions
Acute Cerebral Ischemia
Interventions
DRUG OTHER
No Results Yet
NCT05949983 | RECRUITING | NA
866 Participants

Health Economic Evaluation of an Adapted Physical Activity Program for Women With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-12-23
Completion: 2027-12-31
Conditions
Breast Neoplasm
Interventions
OTHER
No Results Yet
NCT05914558 | WITHDRAWN
0 Participants

Comorbid Painful TMD Among Trigeminal Neuralgia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2022-08-01
Completion: 2026-08-30
Conditions
Trigeminal Neuralgia Temporomandibular Disorder Myofascial Pain Trigeminal Neuropathy
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05909917 | COMPLETED | NA
658 Participants

Deploying Emergency Bystander Internet Training

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-07-15
Completion: 2024-08-31
Conditions
Trauma Trauma Injury
Interventions
OTHER
No Results Yet
NCT05904886 | ACTIVE_NOT_RECRUITING | PHASE3
687 Participants

A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-09-14
Completion: 2025-05-08
Conditions
Hepatocellular Carcinoma
Interventions
DRUG OTHER
No Results Yet
NCT05892068 | RECRUITING | PHASE2
28 Participants

A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-05-09
Completion: 2028-05-09
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT05882058 | RECRUITING | PHASE2
174 Participants

DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-10-13
Completion: 2027-01-29
Conditions
Small Cell Lung Carcinoma Neuroendocrine Neoplasms Extra-pulmonary Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
NCT05866718 | COMPLETED | NA
497 Participants

Can Applying the Science of Habit Formation to Contemplative Practice Improve Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-06-14
Completion: 2024-09-22
Conditions
Psychopathology
Interventions
BEHAVIORAL
No Results Yet
NCT05858229 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
12 Participants

Neo-adjuvant Treatment for Squamous Cell Carcinoma Using Direct Tumor Injection With RP1.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-06-16
Completion: 2025-12-31
Conditions
Squamous Cell Carcinoma RP1
Interventions
DRUG
No Results Yet
NCT05845489 | RECRUITING | PHASE4
11086 Participants

Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis- CloPidogREl for Primary preVENTION (HOST-PREVENTION)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-03-22
Completion: 2028-12-31
Conditions
Coronary Artery Disease
Interventions
DRUG OTHER
No Results Yet
NCT05837806 | RECRUITING | PHASE2
21 Participants

Efficacy and Safety of Tislelizumab in Combination With Disitamab-vedotin as Neoadjuvant Therapy for HER2-positive High-risk Upper Tract Urothelial Carcinoma (UTUC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2022-12-30
Completion: 2026-12-30
Conditions
Neoadjuvant Immunotherapy
Interventions
DRUG
No Results Yet
NCT05800977 | RECRUITING | PHASE1/PHASE2
112 Participants

A Study of C-CAR039 (Prizloncabtagene Autoleucel) in Patients With Relapsed/Refractory Large B-Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-02-22
Completion: 2027-03-31
Conditions
Relapsed/Refractory Large B-Cell Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT05791526 | COMPLETED
308 Participants

An Observational Study to Assess Change in Disease Activity and Adverse Events of Rinvoq in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Japan

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2022-12-19
Completion: 2025-12-09
Conditions
Ulcerative Colitis
No Results Yet
NCT05749874 | ACTIVE_NOT_RECRUITING | PHASE4
2024 Participants

Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-10-31
Completion: 2026-12-31
Conditions
PreDiabetes Abdominal Obesity Hypertension Dyslipidemias Atherosclerotic Cardiovascular Disease
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT05746806 | ACTIVE_NOT_RECRUITING | NA
36 Participants

Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-03-29
Completion: 2027-11-30
Conditions
Recurrent Prostate Cancer
Interventions
RADIATION DRUG
No Results Yet
NCT05724134 | TERMINATED | PHASE1
18 Participants

Pancreatic Clamp in NAFLD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-08-29
Completion: 2025-09-24
Conditions
Insulin Resistance Prediabetic State Hyperinsulinemia Non-Alcoholic Fatty Liver Disease Obesity
Interventions
DRUG OTHER DIETARY_SUPPLEMENT DEVICE
No Results Yet
NCT05717166 | RECRUITING | PHASE3
180 Participants

A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-10-06
Completion: 2029-04-30
Conditions
Metastatic Tumor
Interventions
RADIATION DRUG OTHER PROCEDURE
No Results Yet
NCT05714345 | TERMINATED | PHASE2
2 Participants

Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-11-01
Completion: 2024-02-20
Conditions
Relapsed/Refractory Large B Cell Lymphoma
Interventions
BIOLOGICAL DRUG GENETIC
NCT05691647 | RECRUITING | NA
76 Participants

Chronotherapy for Depressive Episodes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-04-12
Completion: 2029-01-31
Conditions
Depressive Episode
Interventions
BEHAVIORAL
No Results Yet
NCT05682378 | ACTIVE_NOT_RECRUITING | PHASE3
131 Participants

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-02-10
Completion: 2028-03-02
Conditions
Heterozygous or Homozygous Familial Hypercholesterolemia
Interventions
DRUG
No Results Yet
NCT05666778 | ACTIVE_NOT_RECRUITING | PHASE2
408 Participants

Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-02-13
Completion: 2026-06-30
Conditions
Bacterial Vaginosis Vaginal Microbiome Chlamydia Trachomatis Infection Neisseria Gonorrheae Infection Trichomonas Vaginitis
Interventions
DEVICE
No Results Yet
NCT05659966 | ACTIVE_NOT_RECRUITING | NA
228 Participants

Nutritious Eating With Soul Dissemination and Implementation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-04-03
Completion: 2027-03-31
Conditions
Nutrition, Healthy Eating Behavior
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT05658445 | COMPLETED
86 Participants

Potential Role of microRNA 410 and BIRC7 Pathways in Recurrent Spontaneous Miscarriage

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2023-01-01
Completion: 2025-04-01
Conditions
Abortion, Habitual
Interventions
OTHER
No Results Yet
NCT05657301 | ACTIVE_NOT_RECRUITING | PHASE1
25 Participants

Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-10-16
Completion: 2026-09-30
Conditions
Age-Related Macular Degeneration
Interventions
DRUG
No Results Yet
NCT05649722 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
31 Participants

An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-05-11
Completion: 2026-03-14
Conditions
Pulmonary Hypertension Interstitial Lung Disease
Interventions
DRUG
No Results Yet
NCT05646641 | COMPLETED | NA
57 Participants

Strength Training in Fibromyalgia on Balance, Neuromuscular Performance and Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-10-05
Completion: 2025-08-07
Conditions
Fibromyalgia
Interventions
OTHER
No Results Yet
NCT05638295 | RECRUITING | PHASE2
105 Participants

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-08-01
Completion: 2028-12-31
Conditions
Advanced Malignant Solid Neoplasm Metastatic Malignant Solid Neoplasm
Interventions
PROCEDURE BIOLOGICAL DRUG
No Results Yet
NCT05629026 | RECRUITING | NA
60 Participants

Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-02-21
Completion: 2026-02-28
Conditions
Lymphedema
Interventions
PROCEDURE
No Results Yet
NCT05627362 | ACTIVE_NOT_RECRUITING | PHASE2
68 Participants

A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2022-12-29
Completion: 2026-08-28
Conditions
Primary Sclerosing Cholangitis
Interventions
DRUG
No Results Yet
NCT05619627 | NOT_YET_RECRUITING | PHASE1
18 Participants

Oral Dexmedetomidine in Pediatric MRI

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-02-01
Completion: 2027-02-28
Conditions
Anesthesia
Interventions
DRUG
No Results Yet
NCT05616650 | RECRUITING | PHASE2
42 Participants

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-10-19
Completion: 2027-12-01
Conditions
Prostatic Neoplasms Prostate Cancer Prostate Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05615844 | RECRUITING | PHASE3
312 Participants

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-11-05
Completion: 2027-03-31
Conditions
Open tíbia Fracture
Interventions
DRUG DEVICE
No Results Yet
NCT05598112 | RECRUITING | EARLY_PHASE1
210 Participants

Effect of Gut Microbiome Intervention on Aging Via Oral FMT

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-04-24
Completion: 2026-12-31
Conditions
Aging Frailty
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05589688 | RECRUITING | PHASE1
20 Participants

Individualization of Dosage Regimens in Obese Patients: Application to Acyclovir

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-04-09
Completion: 2026-12-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT05559736 | WITHDRAWN | NA
0 Participants

Artemis Proximal Femoral Nail for Internal Fixation of Intertrochanteric Femur Fractures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-05-24
Completion: 2025-12-31
Conditions
Intertrochanteric Fractures Femoral Fracture Femoral Neck Fractures
Interventions
DEVICE
No Results Yet
NCT05554406 | RECRUITING | PHASE2
335 Participants

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-09-25
Completion: 2027-03-31
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Acute Myeloid Leukemia Post Cytotoxic Therapy Acute Myeloid Leukemia, Myelodysplasia-Related
Interventions
DRUG PROCEDURE
No Results Yet
NCT05553522 | TERMINATED | PHASE1
1 Participants

Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2024-01-29
Completion: 2025-12-17
Conditions
Brain Metastases HER2-positive Breast Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05521256 | COMPLETED | PHASE1
70 Participants

A Research Study of a New Medicine NNC0113-6856 in Healthy Males

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2022-08-26
Completion: 2023-03-27
Conditions
Healthy Volunteers Type 2 Diabetes
Interventions
DRUG
No Results Yet
NCT05514340 | RECRUITING | PHASE2
40 Participants

Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-09-06
Completion: 2026-11-30
Conditions
Hypoxic-Ischemic Encephalopathy Neonatal Asphyxia Neonatal Encephalopathy
Interventions
DRUG
No Results Yet
NCT05485831 | RECRUITING
100 Participants

Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2025-02-24
Completion: 2026-01-31
Conditions
Lennox Gastaut Syndrome Dravet Syndrome Tuberous Sclerosis Complex
Interventions
DRUG
No Results Yet
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