Clinical Trials
Showing trials with last updates posted in 2025.
497
Participants
Can Applying the Science of Habit Formation to Contemplative Practice Improve Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-06-14
Completion:
2024-09-22
Conditions
Psychopathology
Interventions
BEHAVIORAL
No Results Yet
12
Participants
Neo-adjuvant Treatment for Squamous Cell Carcinoma Using Direct Tumor Injection With RP1.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-06-16
Completion:
2025-12-31
Conditions
Squamous Cell Carcinoma
RP1
Interventions
DRUG
No Results Yet
11086
Participants
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis- CloPidogREl for Primary preVENTION (HOST-PREVENTION)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-03-22
Completion:
2028-12-31
Conditions
Coronary Artery Disease
Interventions
DRUG
OTHER
No Results Yet
21
Participants
Efficacy and Safety of Tislelizumab in Combination With Disitamab-vedotin as Neoadjuvant Therapy for HER2-positive High-risk Upper Tract Urothelial Carcinoma (UTUC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2022-12-30
Completion:
2026-12-30
Conditions
Neoadjuvant Immunotherapy
Interventions
DRUG
No Results Yet
112
Participants
A Study of C-CAR039 (Prizloncabtagene Autoleucel) in Patients With Relapsed/Refractory Large B-Cell Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-02-22
Completion:
2027-03-31
Conditions
Relapsed/Refractory Large B-Cell Lymphoma
Interventions
BIOLOGICAL
No Results Yet
308
Participants
An Observational Study to Assess Change in Disease Activity and Adverse Events of Rinvoq in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Japan
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2022-12-19
Completion:
2025-12-09
Conditions
Ulcerative Colitis
No Results Yet
2024
Participants
Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-10-31
Completion:
2026-12-31
Conditions
PreDiabetes
Abdominal Obesity
Hypertension
Dyslipidemias
Atherosclerotic Cardiovascular Disease
Interventions
DRUG
BEHAVIORAL
No Results Yet
36
Participants
Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-03-29
Completion:
2027-11-30
Conditions
Recurrent Prostate Cancer
Interventions
RADIATION
DRUG
No Results Yet
180
Participants
A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-10-06
Completion:
2029-04-30
Conditions
Metastatic Tumor
Interventions
RADIATION
DRUG
OTHER
PROCEDURE
No Results Yet
2
Participants
Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-11-01
Completion:
2024-02-20
Conditions
Relapsed/Refractory Large B Cell Lymphoma
Interventions
BIOLOGICAL
DRUG
GENETIC
76
Participants
Chronotherapy for Depressive Episodes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-04-12
Completion:
2029-01-31
Conditions
Depressive Episode
Interventions
BEHAVIORAL
No Results Yet
131
Participants
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-02-10
Completion:
2028-03-02
Conditions
Heterozygous or Homozygous Familial Hypercholesterolemia
Interventions
DRUG
No Results Yet
408
Participants
Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-02-13
Completion:
2026-06-30
Conditions
Bacterial Vaginosis
Vaginal Microbiome
Chlamydia Trachomatis Infection
Neisseria Gonorrheae Infection
Trichomonas Vaginitis
Interventions
DEVICE
No Results Yet
228
Participants
Nutritious Eating With Soul Dissemination and Implementation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-04-03
Completion:
2027-03-31
Conditions
Nutrition, Healthy
Eating Behavior
Interventions
BEHAVIORAL
OTHER
No Results Yet
86
Participants
Potential Role of microRNA 410 and BIRC7 Pathways in Recurrent Spontaneous Miscarriage
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2023-01-01
Completion:
2025-04-01
Conditions
Abortion, Habitual
Interventions
OTHER
No Results Yet
25
Participants
Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-10-16
Completion:
2026-09-30
Conditions
Age-Related Macular Degeneration
Interventions
DRUG
No Results Yet
31
Participants
An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-05-11
Completion:
2026-03-14
Conditions
Pulmonary Hypertension
Interstitial Lung Disease
Interventions
DRUG
No Results Yet
57
Participants
Strength Training in Fibromyalgia on Balance, Neuromuscular Performance and Symptoms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-10-05
Completion:
2025-08-07
Conditions
Fibromyalgia
Interventions
OTHER
No Results Yet
105
Participants
Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-08-01
Completion:
2028-12-31
Conditions
Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Interventions
PROCEDURE
BIOLOGICAL
DRUG
No Results Yet
60
Participants
Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-02-21
Completion:
2026-02-28
Conditions
Lymphedema
Interventions
PROCEDURE
No Results Yet
68
Participants
A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2022-12-29
Completion:
2026-08-28
Conditions
Primary Sclerosing Cholangitis
Interventions
DRUG
No Results Yet
18
Participants
Oral Dexmedetomidine in Pediatric MRI
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-02-01
Completion:
2027-02-28
Conditions
Anesthesia
Interventions
DRUG
No Results Yet
42
Participants
Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-10-19
Completion:
2027-12-01
Conditions
Prostatic Neoplasms
Prostate Cancer
Prostate Adenocarcinoma
Interventions
DRUG
RADIATION
No Results Yet
312
Participants
Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-11-05
Completion:
2027-03-31
Conditions
Open tÃbia Fracture
Interventions
DRUG
DEVICE
No Results Yet
210
Participants
Effect of Gut Microbiome Intervention on Aging Via Oral FMT
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-04-24
Completion:
2026-12-31
Conditions
Aging
Frailty
Interventions
BIOLOGICAL
OTHER
No Results Yet
20
Participants
Individualization of Dosage Regimens in Obese Patients: Application to Acyclovir
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-04-09
Completion:
2026-12-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
0
Participants
Artemis Proximal Femoral Nail for Internal Fixation of Intertrochanteric Femur Fractures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-05-24
Completion:
2025-12-31
Conditions
Intertrochanteric Fractures
Femoral Fracture
Femoral Neck Fractures
Interventions
DEVICE
No Results Yet
1
Participants
Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-01-29
Completion:
2025-12-17
Conditions
Brain Metastases
HER2-positive Breast Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
70
Participants
A Research Study of a New Medicine NNC0113-6856 in Healthy Males
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2022-08-26
Completion:
2023-03-27
Conditions
Healthy Volunteers
Type 2 Diabetes
Interventions
DRUG
No Results Yet
40
Participants
Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-09-06
Completion:
2026-11-30
Conditions
Hypoxic-Ischemic Encephalopathy
Neonatal Asphyxia
Neonatal Encephalopathy
Interventions
DRUG
No Results Yet
100
Participants
Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2025-02-24
Completion:
2026-01-31
Conditions
Lennox Gastaut Syndrome
Dravet Syndrome
Tuberous Sclerosis Complex
Interventions
DRUG
No Results Yet
50
Participants
Identification of Human Biomarkers Predictive of Diabetes Remission in Type 2 Diabetes Patient (BARIAKINES)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-02-27
Completion:
2025-12-31
Conditions
Type 2 Diabetes
Interventions
PROCEDURE
No Results Yet
826
Participants
Tranexamic Acid to Reduce Delirium After Gastrointestinal Surgery: the TRIGS-D Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2022-11-01
Completion:
2026-08-13
Conditions
Surgical Site Infection
Dementia
Cognition
Interventions
DRUG
No Results Yet
184
Participants
"Natural" and "Organic" Cigarette Descriptors: Association With Expectancies, Subjective Effects, Topography, and Biomarkers of Exposure Among Daily Smokers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2022-01-20
Completion:
2024-08-31
Conditions
Smoking Behaviors
Interventions
OTHER
No Results Yet
150
Participants
Lazertinib for NSCLC Harboring Activating EGFR Mutations in TKI naïve Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-01-02
Completion:
2026-03-31
Conditions
NSCLC
Interventions
DRUG
No Results Yet
35
Participants
Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-05-17
Completion:
2025-09-29
Conditions
Healthy
Lower Limb Injury
Post-Traumatic Osteoarthritis
Interventions
DEVICE
No Results Yet
63
Participants
Effects of Unilateral Step Training on Gait and Balance in Stroke Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-01-01
Completion:
2024-06-30
Conditions
Stroke
Interventions
OTHER
No Results Yet
53
Participants
Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-05-01
Completion:
2027-08-31
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
120
Participants
Randomized Clinical Trial for Ewing Amputation in the VA
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2026-01-15
Completion:
2030-01-15
Conditions
Peripheral Arterial Disease
Interventions
PROCEDURE
No Results Yet
190
Participants
Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2023-03-30
Completion:
2030-03-09
Conditions
Locally Advanced Uterine Corpus Leiomyosarcoma
Metastatic Uterine Corpus Leiomyosarcoma
Stage III Uterine Corpus Leiomyosarcoma AJCC v8
Stage IV Uterine Corpus Leiomyosarcoma AJCC v8
Unresectable Uterine Corpus Leiomyosarcoma
Interventions
PROCEDURE
DRUG
No Results Yet
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