Clinical Trials

Showing trials with last updates posted in 2025.

NCT05064826 | ACTIVE_NOT_RECRUITING | NA
170 Participants

ED Observation for Opioid Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2022-04-21
Completion: 2025-06-01
Conditions
Opioid Use Disorder
Interventions
OTHER
No Results Yet
NCT05058313 | COMPLETED | NA
25 Participants

Evaluation of the Safety and Performance of the MILTA GYNECO Vaginal Probe in Postmenopausal Women With Vaginal Atrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2022-03-29
Completion: 2023-06-13
Conditions
Menopause Urinary Incontinence Atrophic Vaginitis
Interventions
DEVICE
No Results Yet
NCT05048212 | RECRUITING | PHASE2
20 Participants

A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2022-09-20
Completion: 2027-01-31
Conditions
Brain Metastases Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT05039515 | ACTIVE_NOT_RECRUITING | PHASE2
113 Participants

A Study to Assess the Effectiveness and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP).

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-12-01
Completion: 2029-03-30
Conditions
Fibrodysplasia Ossificans Progressiva
Interventions
DRUG
No Results Yet
NCT05030493 | ACTIVE_NOT_RECRUITING
787 Participants

An Additional Analysis of Data From the PARADIGM Exploratory Study (NCT02394834) in Patients With Advanced/Recurrent Colorectal Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2021-08-31
Completion: 2027-07-31
Conditions
Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT05030428 | ACTIVE_NOT_RECRUITING | PHASE3
17004 Participants

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-11-23
Completion: 2027-10-13
Conditions
Atherosclerotic Cardiovascular Disease
Interventions
DRUG
No Results Yet
NCT05021562 | ACTIVE_NOT_RECRUITING
354 Participants

A Study of Niraparib in Patients With Ovarian Cancer in Clinical Practice

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2021-09-13
Completion: 2026-03-31
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT05011903 | NOT_YET_RECRUITING | NA
600 Participants

Integrative Alcohol and Risky Sex Feedback for College Students

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2026-02-01
Completion: 2027-01-31
Conditions
Alcohol Drinking in College Sexual Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT05004896 | COMPLETED | PHASE2
71 Participants

Ketamine for Treatment-Resistant Bipolar Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2022-07-04
Completion: 2025-11-14
Conditions
Bipolar Disorder Bipolar Depression Bipolar I Disorder Bipolar II Disorder
Interventions
DRUG
No Results Yet
NCT04991103 | RECRUITING | PHASE2
40 Participants

Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-09-22
Completion: 2027-01-01
Conditions
Multiple Myeloma Amyloidosis
Interventions
DRUG
No Results Yet
NCT04980092 | SUSPENDED
100 Participants

Assessment of Kidney Function and Osteomuscular Status After Critical Care

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2023-03-01
Completion: 2026-03-31
Conditions
Critical Illness Kidney Injury Muscle Loss Bone Loss
Interventions
OTHER
No Results Yet
NCT04952779 | COMPLETED
750 Participants

Regulatory Post Marketing Surveillance (rPMS) Study of XultophyĀ® (Insulin Degludec/Liraglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2021-06-02
Completion: 2024-12-15
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT04930445 | TERMINATED
265 Participants

OxbrytaĀ® Product Registry An Observational Study Designed to Evaluate the Effect of Oxbryta in Individuals With SCD

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2022-02-04
Completion: 2024-10-10
Conditions
Sickle Cell Disease
Interventions
DRUG
NCT04930159 | ACTIVE_NOT_RECRUITING | NA
252 Participants

Social Interventions for Support During Treatment for Endometrial Cancer and Recurrence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-09-01
Completion: 2026-03-30
Conditions
Endometrial Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT04912505 | COMPLETED | PHASE2
4 Participants

ASPirin in Immune thRombocytopenia Patients With Cardiovascular disEase

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2023-01-16
Completion: 2024-01-02
Conditions
Purpura, Thrombocytopenic
Interventions
DRUG
No Results Yet
NCT04838743 | COMPLETED
244 Participants

GOAL: A Research Study Looking at Long Term Blood Sugar Control in People With Type 2 Diabetes Treated With XultophyĀ® in Local Clinical Practice in Japan.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2021-04-23
Completion: 2022-10-26
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT04835805 | ACTIVE_NOT_RECRUITING | PHASE1
65 Participants

A Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients With NRAS-mutant Advanced Melanoma.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-05-13
Completion: 2025-12-31
Conditions
Melanoma
Interventions
DRUG
No Results Yet
NCT04821089 | RECRUITING | PHASE1/PHASE2
727 Participants

A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Moderate to Severe Upper Facial Lines

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-04-06
Completion: 2026-08-31
Conditions
Moderate to Severe Upper Facial Lines
Interventions
BIOLOGICAL
No Results Yet
NCT04805788 | TERMINATED | PHASE2
9 Participants

Stereotactic Body Proton Radiotherapy for the Treatment of Liver Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-08-24
Completion: 2024-02-15
Conditions
Recurrent Hepatocellular Carcinoma Stage I Hepatocellular Carcinoma AJCC v8 Stage II Hepatocellular Carcinoma AJCC v8 Stage III Hepatocellular Carcinoma AJCC v8
Interventions
RADIATION OTHER
No Results Yet
NCT04803214 | ACTIVE_NOT_RECRUITING | NA
203 Participants

ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-07-14
Completion: 2024-09-04
Conditions
Chronic Low-back Pain
Interventions
DEVICE
NCT04800484 | RECRUITING | NA
40 Participants

The Effects of AFO Heel Height and Stiffness on Gait

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2019-11-07
Completion: 2027-01-01
Conditions
Musculoskeletal Injury Musculoskeletal Diseases Peripheral Nervous System Diseases
Interventions
DEVICE
No Results Yet
NCT04779957 | COMPLETED | PHASE2
18 Participants

Evaluation of the Safety of Use of Anti-IL6 Receptor Antibodies to Reduce Allo-sensitization Post Allograft Nephrectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-10-01
Completion: 2024-08-09
Conditions
Kidney Transplantation Graft Failure
Interventions
DRUG
No Results Yet
NCT04777409 | ACTIVE_NOT_RECRUITING | PHASE3
1840 Participants

A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-05-18
Completion: 2025-09-15
Conditions
Early Alzheimer“s Disease
Interventions
DRUG
No Results Yet
NCT04763980 | RECRUITING | NA
72 Participants

Community-Based Health Coach for Access to Germline Genetic Testing Among African American Men With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-01-15
Completion: 2027-03-31
Conditions
Prostate Carcinoma
Interventions
OTHER
No Results Yet
NCT04747431 | RECRUITING | PHASE1/PHASE2
30 Participants

A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-09-14
Completion: 2028-08-31
Conditions
Frontotemporal Dementia FTD FTD-GRN Dementia Frontotemporal C9orf72
Interventions
DRUG
No Results Yet
NCT04745221 | RECRUITING | NA
100 Participants

Efficacy and Safety of Auto-FMT in Preventing aGVHD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-03-01
Completion: 2026-03-01
Conditions
Graft Versus Host Disease, Acute
Interventions
OTHER
No Results Yet
NCT04737720 | COMPLETED
1 Participants

Intravenous ACP-501 for Familial LCAT Deficiency (rhLCAT)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2013-01-24
Completion: 2013-12-12
Conditions
Familial LCAT Deficiency
Interventions
DRUG
No Results Yet
NCT04737460 | ACTIVE_NOT_RECRUITING | PHASE1
4 Participants

Study for the Treatment for CLN7 Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-05-04
Completion: 2028-02-01
Conditions
CLN7
Interventions
GENETIC
No Results Yet
NCT04708470 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
55 Participants

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-10-05
Completion: 2026-11-30
Conditions
Oropharyngeal Cancer Neck Cancer Human Papillomavirus HPV Anal Cancer Cervical Cancer Penile Cancer Vulvar Cancer Vaginal Cancer Colon Cancer
Interventions
DRUG
No Results Yet
NCT04685200 | RECRUITING
143 Participants

Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2023-03-31
Completion: 2026-10-31
Conditions
Primary Sclerosing Cholangitis
No Results Yet
NCT04660487 | RECRUITING
100 Participants

Relationship Between "FODMAPs" and "GVHD"

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2020-12-01
Completion: 2026-12-01
Conditions
Graft Versus Host Disease
No Results Yet
NCT04621435 | RECRUITING | PHASE1
191 Participants

Imaging of Solid Tumors Using FAP-2286

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2020-12-14
Completion: 2026-12-31
Conditions
Solid Tumors, Adult Metastatic Cancer
Interventions
DRUG PROCEDURE
No Results Yet
NCT04609072 | RECRUITING
200000 Participants

Connect for Cancer Prevention Study (Connect)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2021-07-26
Completion: 2070-12-31
Conditions
Cancer General Research Use
No Results Yet
NCT04601857 | TERMINATED | PHASE2
43 Participants

Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-01-07
Completion: 2024-03-08
Conditions
Advanced and Metastatic Urothelial Cancer
Interventions
DRUG
NCT04560673 | RECRUITING | PHASE2
380 Participants

Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2020-07-10
Completion: 2026-12-31
Conditions
Chemotherapy-Induced Peripheral Neuropathy Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
DRUG BEHAVIORAL OTHER
No Results Yet
NCT04557969 | RECRUITING
400 Participants

Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2020-12-18
Completion: 2040-12-30
Conditions
Gastric Cancer Gastric Neoplasm Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Neoplasm Gastrointestinal Stromal Tumor (GIST)
No Results Yet
NCT04542733 | RECRUITING | NA
50 Participants

The Efficacy of Everolimus With Reduced-dose Tacrolimus Versus Reduced-dose Tacrolimus and Leflunomide in Treatment of BK Virus Infection in Kidney Transplantation Recipient

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-02-10
Completion: 2025-12-24
Conditions
Kidney Transplant Infection BK Virus Infection
Interventions
DRUG
No Results Yet
NCT04469855 | COMPLETED
3217 Participants

Post-Marketing Surveillance (Special Use-results Surveillance) on Long-term Use With OzempicĀ®

Study Type: OBSERVATIONAL
Last Updated: 2025-12-31
Start Date: 2020-07-27
Completion: 2025-05-12
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT04453917 | COMPLETED | NA
22 Participants

Dynamics of T Cell Expression of Immune Checkpoint Molecules in Progressive Multifocal Leukoencephalopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2021-02-23
Completion: 2024-07-12
Conditions
Progressive Multifocal Leukoencephalopathy
Interventions
BIOLOGICAL DIAGNOSTIC_TEST
No Results Yet
NCT04451135 | ACTIVE_NOT_RECRUITING | NA
31 Participants

CET- REM (Correlating ECT Response to EEG Markers)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-31
Start Date: 2020-10-09
Completion: 2026-06-30
Conditions
ECT Treatment Resistant Depression
Interventions
DIAGNOSTIC_TEST
No Results Yet
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