Clinical Trials Updated in 2025

NCT07297966 | RECRUITING | PHASE2

120 Participants

Evaluation of the Clinical Efficacy of Antrrix Probiotics in Improving Recurrent Respiratory Infections in Infants and Young Children

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-05-14

Completion: 2026-01-31

Conditions

Recurrent Respiratory Tract Infections

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07297602 | RECRUITING | PHASE2

36 Participants

Evaluation of Efficacy and Safety of Oral Roflumilast for Treatment of Moderate to Severe Atopic Dermatitis in Patients Aged 12 Years and Older: A Pilot Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-20

Completion: 2026-05-20

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT07297576 | RECRUITING | NA

36 Participants

Safety and Feasibility of Sulforaphane to Promote Early Haematopoietic Recovery After Cord Blood Transplantation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-10-22

Completion: 2027-06-30

Conditions

ALL (Acute B-Lymphoblastic Leukemia) AML (Acute Myelogenous Leukemia MDS (Myelodysplastic Syndrome)

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07297537 | NOT_YET_RECRUITING | NA

18 Participants

Adductor Endurance Test: Validity and Reliability

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2026-04-15

Completion: 2026-09-15

Conditions

Groin Injury Hip Injuries Athletic Injuries

Interventions

OTHER

No Results Yet

NCT07297459 | ENROLLING_BY_INVITATION

65 Participants

Arthroscopic Anterior Release Versus Discectomy as Treatments for Temporomandibular Joint Disc Displacement With Reduction

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2025-09-16

Completion: 2027-12-31

Conditions

TMJ - Injury of Meniscus of Temporomandibular Joint TMD TMJ - Oral &Amp;Maxillofacial Surgery

No Results Yet

NCT07297277 | RECRUITING

85 Participants

Evaluating the Level of Agreement Between AAMI/ESH/ISO Universal Standard Requirements and the HUAWEI D2 Watch-Type Wrist Blood Pressure Monitor

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2025-07-15

Completion: 2027-10-31

Conditions

Blood Pressure Monitoring

No Results Yet

NCT07296809 | NOT_YET_RECRUITING | PHASE2

80 Participants

SKB500 Combinations in Patients With Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-20

Completion: 2028-12-31

Conditions

Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07295366 | RECRUITING | PHASE4

60 Participants

Early Administration of PCSK9 Inhibitors After Thrombectomy for Atherosclerotic Acute Ischemic Stroke: A Randomized Controlled Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-18

Completion: 2026-08-30

Conditions

Acute Stroke

Interventions

DRUG

No Results Yet

NCT07294313 | NOT_YET_RECRUITING

400 Participants

Harnessing Artificial Intelligence for Diagnosing Androgenetic Alopecia: A Training and Validation Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-25

Completion: 2026-09-25

Conditions

Androgenetic Alopecia

No Results Yet

NCT07292558 | RECRUITING | NA

306 Participants

Achieving Health in Emerging Adults With Diabetes (AHEAD) Program: A Clinical Trial Designed to Understand if Participation in a Clinical Program Developed Specifically to Support Emerging Adults With Type 1 Diabetes Leads to Improved Diabetes Outcomes.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-15

Completion: 2028-12-31

Conditions

Diabetes Mellitus, Type 1 Diabetes

Interventions

BEHAVIORAL

No Results Yet

NCT07291843 | RECRUITING | NA

48 Participants

Vibration Therapy and IASTM in Subacromial Impingement Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-10

Completion: 2026-02-01

Conditions

Impingement Syndrome Impingement Shoulder Shoulder Pain

Interventions

DEVICE OTHER

No Results Yet

NCT07291128 | RECRUITING | NA

40 Participants

Effects of VOJTA Technique on Ataxic Cerebral Palsy.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-08

Completion: 2026-05-31

Conditions

Ataxic Cerebral Palsy

Interventions

BEHAVIORAL

No Results Yet

NCT07288385 | RECRUITING | NA

100 Participants

Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Upper Limb Recovery in Patients With Stroke

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-28

Completion: 2026-12-30

Conditions

Brain Diseases Central Nervous System Diseases Nervous System Diseases Stroke Paresis

Interventions

DEVICE OTHER

No Results Yet

NCT07287033 | RECRUITING | PHASE1

48 Participants

Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-06

Completion: 2027-04-30

Conditions

Peanut Allergies

Interventions

DRUG

No Results Yet

NCT07286578 | RECRUITING | NA

700 Participants

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-23

Completion: 2029-12-15

Conditions

Cardiovascular Diseases Myocardial Ischemia Heart Diseases Arteriosclerosis Arterial Occlusive Diseases Vascular Diseases Coronary Artery Disease

Interventions

DEVICE

No Results Yet

NCT07285902 | RECRUITING | PHASE3

750 Participants

A Study Comparing the Efficacy and Safety of HRS9531 Injection With Semaglutide Injection in Subjects With Obesity

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-25

Completion: 2027-03-31

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT07285473 | NOT_YET_RECRUITING | PHASE2

75 Participants

Low-Dose Naltrexone For ME/CFS: Dose-Finding

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2026-04-01

Completion: 2028-04-01

Conditions

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Interventions

DRUG

No Results Yet

NCT07284186 | RECRUITING | PHASE1

155 Participants

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-31

Completion: 2029-12-31

Conditions

Esophageal Squamous Cell Carcinoma Gastric Adenocarcinoma Gastric Squamous Cell Carcinoma Gastroesophageal Junction (GEJ) Adenocarcinoma Metastatic Solid Tumor Non-Small Cell Lung Carcinoma Esophageal Adenocarcinoma SMARCA4 Mutation Gastroesophageal Junction Squamous Cell Carcinoma Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT07282353 | RECRUITING | PHASE3

135 Participants

A Study of CS0159 in Patients With PBC With Inadequate Response or Intolerance to UDCA

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-01

Completion: 2027-12-09

Conditions

Primary Biliary Cholangitis

Interventions

DRUG

No Results Yet

NCT07281157 | RECRUITING | PHASE2

30 Participants

Irinotecan Liposome Plus Capecitabine and Enronsubemab Combined With Short-course Radiotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-01

Completion: 2027-04-30

Conditions

Advanced Colorectal Cancer

Interventions

DRUG

No Results Yet

NCT07280130 | NOT_YET_RECRUITING

120 Participants

Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2026-02-01

Completion: 2027-06-01

Conditions

Dental Occlusion Occlusal Wear of Teeth Fixed Dental Prosthesis

Interventions

PROCEDURE

No Results Yet

NCT07275489 | RECRUITING

9 Participants

CHOICE KERGUELEN 2 : Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands : Follow-up of Volunteers on the Kerguelen Islands

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-20

Completion: 2026-01-31

Conditions

Human Health in Extreme Conditions

Interventions

OTHER

No Results Yet

NCT07275281 | NOT_YET_RECRUITING

2000 Participants

Incidental Findings on Coronary Computed Tomography Angiography

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2026-01-02

Completion: 2027-01-02

Conditions

Computed Tomography Coronary Angiography Incidental Findings

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07272525 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

1 Participants

Research Study for Single-Patient Treatment of Cree Leukoencephalopathy/Vanishing White Matter Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2024-11-14

Completion: 2027-11-30

Conditions

Cree Leukoencephalopathy Vanishing White Matter

Interventions

DRUG

No Results Yet

NCT07271693 | RECRUITING | PHASE1

128 Participants

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-22

Completion: 2027-03-01

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT07270575 | NOT_YET_RECRUITING

400 Participants

REsorbable SCaffolds With everolimUs-Elution for the Treatment of Infrapopliteal Artery Disease in Patients With Chronic Limb-threatening Ischemia

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2026-04-30

Completion: 2032-04-30

Conditions

Chronic Limb Threatening Ischemia Chronic Limb-Threatening Ischemia

Interventions

DEVICE

No Results Yet

NCT07269444 | COMPLETED

98 Participants

Efficacy of IPACK Block Combined With Intra-articular Steroid Injection in Advanced Knee Osteoarthritis: A Retrospective Cohort Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-05

Completion: 2025-12-10

Conditions

Intraarticular Injection Ultrasound Guided Injection Knee Osteoarthritis (Knee OA) IPACK Block Multimodal Analgesia

No Results Yet

NCT07268105 | NOT_YET_RECRUITING | NA

124 Participants

Flange Fitting for NICU Pumping Parents to Explore Improved Milk Production and Satisfaction

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-01

Completion: 2027-01-02

Conditions

Human Milk/Breastfeeding Breast Pumping

Interventions

OTHER

No Results Yet

NCT07262554 | ACTIVE_NOT_RECRUITING | PHASE2

40 Participants

N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-15

Completion: 2026-06-30

Conditions

Apical Periodontitis

Interventions

DRUG

No Results Yet

NCT07256197 | NOT_YET_RECRUITING | PHASE3

160 Participants

PCSK9 Inhibitors in the Treatment of Calcific Aortic Stenosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2026-01-01

Completion: 2028-12-31

Conditions

Aortic Stenosis, Calcific

Interventions

DRUG OTHER

No Results Yet

NCT07256106 | RECRUITING | NA

28 Participants

Occlusion and Dis-Occlusion Time in Mandibular Overdentures Supported by Conventional Versus Mini- Dental Implants

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-29

Completion: 2026-03-31

Conditions

Dental Implant Edentulous Mouth

Interventions

PROCEDURE

No Results Yet

NCT07249918 | RECRUITING | NA

20 Participants

Feasibility of Wearables in Dementia Care in Rural Taiwan

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-18

Completion: 2026-09-30

Conditions

Alzheimer's Dementia Neuropsychiatric Symptoms Related to Neurodegenerative Disease Wearable Devices Caregiver Burden of People With Dementia Circadian Rhythm

Interventions

DEVICE

No Results Yet

NCT07249489 | NOT_YET_RECRUITING | NA

10 Participants

Nanochon Chondrograft First in Human (FIH) Early Feasibility Study (EFS) - Canada

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-31

Completion: 2027-06-30

Conditions

Knee Cartilage Lesions

Interventions

DEVICE

No Results Yet

NCT07248709 | RECRUITING | NA

68 Participants

Comparison of High-Intensity Interval Training and Moderate-Intensity Continuous Training in Mild Cognitive Impairment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-05

Completion: 2026-04-12

Conditions

Mild Cognitive Impairment

Interventions

OTHER

No Results Yet

NCT07247786 | NOT_YET_RECRUITING | PHASE2

68 Participants

Study for Evaluating the Safety and Feasibility of Fecal Microbiota Transplant in Stage II-III NSCLC Patients Using ICI Responders as Donors (MIGRANT)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2026-03-15

Completion: 2031-12-30

Conditions

Non Small Cell Lung Cancer Respiratory Tract Neoplasm

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT07247110 | RECRUITING | PHASE1

250 Participants

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-16

Completion: 2030-12-01

Conditions

Malignant Neoplasm

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT07246941 | RECRUITING | PHASE1

40 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RG6496 in Huntington's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-11-19

Completion: 2027-12-11

Conditions

Huntington's Disease

Interventions

DRUG

No Results Yet

NCT07241104 | RECRUITING | PHASE1

31 Participants

A Study of AZD4063 in PLN R14del Dilated Cardiomyopathy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-01

Completion: 2027-11-22

Conditions

Dilated Cardiomyopathy

Interventions

DRUG

No Results Yet

NCT07239479 | RECRUITING | NA

40 Participants

DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-01

Completion: 2026-12-31

Conditions

Colorectal Neoplasms

Interventions

DRUG

No Results Yet

NCT07235150 | RECRUITING | PHASE1

76 Participants

A Study to Learn How Different Amounts of the Study Medicine Called PF-07985631 Are Tolerated and Act in the Body in Healthy Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-12-30

Start Date: 2025-12-11

Completion: 2027-07-27

Conditions

Healthy

Interventions

DRUG

No Results Yet