MedDataX Logo

Clinical Trials

Showing trials with last updates posted in 2025.

NCT07285473 | NOT_YET_RECRUITING | PHASE2
75 Participants

Low-Dose Naltrexone For ME/CFS: Dose-Finding

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-04-01
Completion: 2028-04-01
Conditions
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Interventions
DRUG
No Results Yet
NCT07284186 | RECRUITING | PHASE1
155 Participants

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-31
Completion: 2029-12-31
Conditions
Esophageal Squamous Cell Carcinoma Gastric Adenocarcinoma Gastric Squamous Cell Carcinoma Gastroesophageal Junction (GEJ) Adenocarcinoma Metastatic Solid Tumor Non-Small Cell Lung Carcinoma Esophageal Adenocarcinoma SMARCA4 Mutation Gastroesophageal Junction Squamous Cell Carcinoma Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT07282353 | RECRUITING | PHASE3
135 Participants

A Study of CS0159 in Patients With PBC With Inadequate Response or Intolerance to UDCA

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-01
Completion: 2027-12-09
Conditions
Primary Biliary Cholangitis
Interventions
DRUG
No Results Yet
NCT07281157 | RECRUITING | PHASE2
30 Participants

Irinotecan Liposome Plus Capecitabine and Enronsubemab Combined With Short-course Radiotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-01
Completion: 2027-04-30
Conditions
Advanced Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT07280130 | NOT_YET_RECRUITING
120 Participants

Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2026-02-01
Completion: 2027-06-01
Conditions
Dental Occlusion Occlusal Wear of Teeth Fixed Dental Prosthesis
Interventions
PROCEDURE
No Results Yet
NCT07275489 | RECRUITING
9 Participants

CHOICE KERGUELEN 2 : Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands : Follow-up of Volunteers on the Kerguelen Islands

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-20
Completion: 2026-01-31
Conditions
Human Health in Extreme Conditions
Interventions
OTHER
No Results Yet
NCT07275281 | NOT_YET_RECRUITING
2000 Participants

Incidental Findings on Coronary Computed Tomography Angiography

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-02
Completion: 2027-01-02
Conditions
Computed Tomography Coronary Angiography Incidental Findings
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07272525 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
1 Participants

Research Study for Single-Patient Treatment of Cree Leukoencephalopathy/Vanishing White Matter Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-14
Completion: 2027-11-30
Conditions
Cree Leukoencephalopathy Vanishing White Matter
Interventions
DRUG
No Results Yet
NCT07271693 | RECRUITING | PHASE1
128 Participants

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-22
Completion: 2027-03-01
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT07270575 | NOT_YET_RECRUITING
400 Participants

REsorbable SCaffolds With everolimUs-Elution for the Treatment of Infrapopliteal Artery Disease in Patients With Chronic Limb-threatening Ischemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2026-04-30
Completion: 2032-04-30
Conditions
Chronic Limb Threatening Ischemia Chronic Limb-Threatening Ischemia
Interventions
DEVICE
No Results Yet
NCT07269444 | COMPLETED
98 Participants

Efficacy of IPACK Block Combined With Intra-articular Steroid Injection in Advanced Knee Osteoarthritis: A Retrospective Cohort Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-05
Completion: 2025-12-10
Conditions
Intraarticular Injection Ultrasound Guided Injection Knee Osteoarthritis (Knee OA) IPACK Block Multimodal Analgesia
No Results Yet
NCT07268105 | NOT_YET_RECRUITING | NA
124 Participants

Flange Fitting for NICU Pumping Parents to Explore Improved Milk Production and Satisfaction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-01
Completion: 2027-01-02
Conditions
Human Milk/Breastfeeding Breast Pumping
Interventions
OTHER
No Results Yet
NCT07262554 | ACTIVE_NOT_RECRUITING | PHASE2
40 Participants

N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-15
Completion: 2026-06-30
Conditions
Apical Periodontitis
Interventions
DRUG
No Results Yet
NCT07256197 | NOT_YET_RECRUITING | PHASE3
160 Participants

PCSK9 Inhibitors in the Treatment of Calcific Aortic Stenosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-01
Completion: 2028-12-31
Conditions
Aortic Stenosis, Calcific
Interventions
DRUG OTHER
No Results Yet
NCT07256106 | RECRUITING | NA
28 Participants

Occlusion and Dis-Occlusion Time in Mandibular Overdentures Supported by Conventional Versus Mini- Dental Implants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-29
Completion: 2026-03-31
Conditions
Dental Implant Edentulous Mouth
Interventions
PROCEDURE
No Results Yet
NCT07249918 | RECRUITING | NA
20 Participants

Feasibility of Wearables in Dementia Care in Rural Taiwan

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-18
Completion: 2026-09-30
Conditions
Alzheimer's Dementia Neuropsychiatric Symptoms Related to Neurodegenerative Disease Wearable Devices Caregiver Burden of People With Dementia Circadian Rhythm
Interventions
DEVICE
No Results Yet
NCT07249489 | NOT_YET_RECRUITING | NA
10 Participants

Nanochon Chondrograft First in Human (FIH) Early Feasibility Study (EFS) - Canada

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-31
Completion: 2027-06-30
Conditions
Knee Cartilage Lesions
Interventions
DEVICE
No Results Yet
NCT07248709 | RECRUITING | NA
68 Participants

Comparison of High-Intensity Interval Training and Moderate-Intensity Continuous Training in Mild Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-05
Completion: 2026-04-12
Conditions
Mild Cognitive Impairment
Interventions
OTHER
No Results Yet
NCT07247786 | NOT_YET_RECRUITING | PHASE2
68 Participants

Study for Evaluating the Safety and Feasibility of Fecal Microbiota Transplant in Stage II-III NSCLC Patients Using ICI Responders as Donors (MIGRANT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-03-15
Completion: 2031-12-30
Conditions
Non Small Cell Lung Cancer Respiratory Tract Neoplasm
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT07247110 | RECRUITING | PHASE1
250 Participants

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-16
Completion: 2030-12-01
Conditions
Malignant Neoplasm
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT07246941 | RECRUITING | PHASE1
40 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RG6496 in Huntington's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-19
Completion: 2027-12-11
Conditions
Huntington's Disease
Interventions
DRUG
No Results Yet
NCT07241104 | RECRUITING | PHASE1
31 Participants

A Study of AZD4063 in PLN R14del Dilated Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-01
Completion: 2027-11-22
Conditions
Dilated Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT07239479 | RECRUITING | NA
40 Participants

DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-01
Completion: 2026-12-31
Conditions
Colorectal Neoplasms
Interventions
DRUG
No Results Yet
NCT07235150 | RECRUITING | PHASE1
76 Participants

A Study to Learn How Different Amounts of the Study Medicine Called PF-07985631 Are Tolerated and Act in the Body in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-11
Completion: 2027-07-27
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT07235046 | RECRUITING | PHASE2
200 Participants

A Study of DII235 in Adults With Elevated Lipoprotein(a)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-02
Completion: 2027-09-08
Conditions
Lipoprotein Disorder
Interventions
DRUG
No Results Yet
NCT07233408 | RECRUITING | NA
50 Participants

Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-31
Completion: 2026-05-30
Conditions
Neurofibromatosis 1
Interventions
OTHER
No Results Yet
NCT07232667 | NOT_YET_RECRUITING | NA
140 Participants

Digital Technology for Active and Healthy Ageing in Taiwan

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-02-01
Completion: 2028-12-31
Conditions
Healthy Aging Digital Health Literacy
Interventions
DEVICE BEHAVIORAL BIOLOGICAL
No Results Yet
NCT07231484 | RECRUITING | NA
50 Participants

Effects of Grape Consumption on the Immune-Gut Axis in Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-19
Completion: 2027-12-20
Conditions
Obesity &Amp; Overweight
Interventions
OTHER
No Results Yet
NCT07229404 | ACTIVE_NOT_RECRUITING | PHASE1
16 Participants

A Study to Investigate Relative Bioavailability, Safety and Tolerability of Single- and Multiple-doses of Elinzanetant in Healthy Female Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-05
Completion: 2026-01-21
Conditions
Vasomotor Symptoms
Interventions
DRUG
No Results Yet
NCT07229235 | NOT_YET_RECRUITING
50 Participants

REAL-CARE: Real-world Effectiveness of Iptacopan in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-31
Completion: 2028-08-31
Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
No Results Yet
NCT07226947 | RECRUITING | NA
100 Participants

Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-24
Completion: 2027-06-30
Conditions
Obesity Body Composition
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT07226687 | NOT_YET_RECRUITING | NA
338 Participants

Evaluating the Impact of Small Versus Large Urethral Stiches (or 'Bites') on Urinary Continence.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-09-30
Completion: 2031-05-23
Conditions
Prostatectomy
Interventions
PROCEDURE
No Results Yet
NCT07226609 | RECRUITING | NA
220 Participants

A Dietary Study for People With Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-04
Completion: 2028-11-30
Conditions
Multiple Myeloma
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT07224373 | RECRUITING | PHASE1
24 Participants

An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-09
Completion: 2028-12-08
Conditions
Multiple Sclerosis
Interventions
BIOLOGICAL
No Results Yet
NCT07223229 | RECRUITING | PHASE2
45 Participants

Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-30
Completion: 2026-12-31
Conditions
Non-segmental Vitiligo
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT07220564 | RECRUITING | PHASE1
20 Participants

A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-23
Completion: 2026-12-21
Conditions
Haemophilia A
Interventions
DRUG
No Results Yet
NCT07220343 | RECRUITING | NA
25 Participants

Digital Phenotyping for Psychosocial Screening in Adolescents and Young Adults With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-01-29
Completion: 2026-12-31
Conditions
Cancer Adolescents
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT07218016 | RECRUITING | NA
288 Participants

The AccelERate Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-02
Completion: 2028-03-31
Conditions
Pelvic Organ Prolapse Pelvic Organ Prolapse (POP) Pelvic Organ Prolapse Vaginal Surgery Pelvic Organ Prolapse, Patient Education
Interventions
BEHAVIORAL
No Results Yet
NCT07217171 | RECRUITING | PHASE1
160 Participants

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-13
Completion: 2029-01-29
Conditions
Bladder Cancer Squamous Cell Carcinoma of the Lung Esophageal Squamous Cell Carcinoma Tongue Squamous Cell Carcinoma Cutaneous Squamous Cell Cancer Penile Squamous Cell Carcinoma Anal Squamous Cell Carcinoma Vulvar Squamous Cell Carcinoma Cervical Squamous Cell Carcinoma Vaginal Squamous Cell Carcinoma Urethral Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07213791 | RECRUITING | PHASE1
241 Participants

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-22
Completion: 2028-07-31
Conditions
Ovarian Neoplasms Breast Neoplasms Pancreatic Intraductal Neoplasms Colorectal Neoplasms Esophageal Neoplasms Stomach Neoplasms Cholangiocarcinoma
Interventions
DRUG
No Results Yet
Previous
Sorted by latest updates
Next
Showing 40 trials per page