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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07207070 | RECRUITING | PHASE3
312 Participants

A Randomised, Open-label, Multicentre Phase III Clinical Study to Evaluate the Efficacy and Safety of JS105 Combined With Dalpiciclib and Fulvestrant Compared With Dalpiciclib and Fulvestrant in Patients With PIK3CA-mutated, HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-12
Completion: 2029-05-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT07206576 | COMPLETED | NA
32 Participants

Acute Effects of Percussion Massage Therapy in Adolescent Cyclists

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-09-30
Completion: 2025-11-14
Conditions
Balanced
Interventions
DEVICE
No Results Yet
NCT07203001 | RECRUITING | PHASE2
20 Participants

A Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-03
Completion: 2029-05-24
Conditions
Still´s Disease
Interventions
DRUG
No Results Yet
NCT07195682 | RECRUITING | PHASE1
125 Participants

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-31
Completion: 2030-05-03
Conditions
Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07190755 | RECRUITING | NA
192 Participants

Impact of Patient-Reported Outcomes for Symptom Monitoring in Patients Followed for Head and Neck Squamous Cell Carcinoma (HNSCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-15
Completion: 2030-06-01
Conditions
Head and Neck Squamous Cell Carcinoma HNSCC
Interventions
OTHER
No Results Yet
NCT07190547 | COMPLETED | NA
120 Participants

Helfer Technique and ShotBlocker in Reducing Pain, Fear, and Anxiety in Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-09-25
Completion: 2025-10-15
Conditions
Children Preschool Pain Management
Interventions
OTHER
No Results Yet
NCT07176468 | RECRUITING | NA
40 Participants

Personalized iTBS in Real-World Clinical Settings for Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-20
Completion: 2026-09-20
Conditions
Schizophrenia Transcranial Magnetic Stimulation
Interventions
OTHER
No Results Yet
NCT07170735 | NOT_YET_RECRUITING
85 Participants

Quantitative Measurement of Plasma and Urine MTB Cell-free DNA Level

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-01
Completion: 2027-03-31
Conditions
Tuberculosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07170644 | RECRUITING | PHASE2
18 Participants

A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-08-08
Completion: 2028-05-31
Conditions
Desmoid Tumor Aggressive Fibromatosis
Interventions
DRUG
No Results Yet
NCT07166861 | NOT_YET_RECRUITING | NA
6080 Participants

Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-01
Completion: 2029-09-30
Conditions
Aging Preventive Care Multimorbidity Palliative Care
Interventions
OTHER
No Results Yet
NCT07161284 | ACTIVE_NOT_RECRUITING | NA
520 Participants

Impact of Mental Health First Aid-trained Peers on the Mental Well-being of First-year Medical Residents.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-11-21
Completion: 2026-12-31
Conditions
Mental Well-being
Interventions
OTHER
No Results Yet
NCT07159737 | NOT_YET_RECRUITING | NA
800 Participants

Comparison of HYBRID Versus Two-Stent Strategies in Unprotected True Left MAIN Bifurcation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-01
Completion: 2028-01-01
Conditions
Unprotected Left Main Coronary Artery Disease
Interventions
PROCEDURE
No Results Yet
NCT07148050 | RECRUITING | PHASE1
21 Participants

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-22
Completion: 2029-04-22
Conditions
Solid Tumor (Excluding CNS) Liver Cell Carcinoma Malignant Rhabdoid Tumor Yolk Sac Tumor Liposarcoma Rhabdomyosarcoma Embryonal Sarcoma of Liver Wilms Tumor Hepatocellular Carcinoma Hepatoblastoma
Interventions
BIOLOGICAL
No Results Yet
NCT07141264 | RECRUITING | PHASE2
32 Participants

Adebrelimab Combine With Etoposide Capsules in ES-SCLC Maintenance Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-08-25
Completion: 2026-12-30
Conditions
SCLC,Extensive Stage
Interventions
DRUG
No Results Yet
NCT07140809 | RECRUITING | PHASE1/PHASE2
48 Participants

a Phase 1b/2a Study of JMT202 Injection in Participants With Hypertriglyceridemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-09-09
Completion: 2026-07-31
Conditions
Hypertriglyceridemia
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT07138196 | RECRUITING | PHASE1
18 Participants

A Study to Evaluate Adrixetinib (Q702) in Adults With Active Chronic Graft-Versus-Host Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-23
Completion: 2029-10-23
Conditions
Chronic Graft-Versus-Host Disease
Interventions
DRUG
No Results Yet
NCT07135154 | ACTIVE_NOT_RECRUITING
205 Participants

Postoperative Opioid Consumption in Gastric Sleeve Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-06-03
Completion: 2025-03-29
Conditions
Obesity &Amp; Overweight General Anesthetic Ketamine
No Results Yet
NCT07132814 | RECRUITING | NA
40 Participants

Abuse Liability for Five Modern Oral Nicotine Products

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-15
Completion: 2026-04-15
Conditions
Smoking Behaviors Tobacco Use Tobacco Smoking Smoking
Interventions
OTHER
No Results Yet
NCT07131254 | RECRUITING | EARLY_PHASE1
34 Participants

A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in Adult Participants With Relapsed/Refractory CD19-positive B-cell Malignant Hematological Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-10
Completion: 2027-12-01
Conditions
Hematological Malignancy (Leukemia- Lymphoma)
Interventions
BIOLOGICAL
No Results Yet
NCT07125586 | RECRUITING | NA
353 Participants

Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity Spectroscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-08-26
Completion: 2028-01-01
Conditions
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07121244 | RECRUITING | PHASE1
62 Participants

A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-01
Completion: 2028-06-01
Conditions
Locoregionally Recurrent Hormone-receptor Positive Breast Cancer Metastatic Hormone Receptor Positive Breast Cancer
Interventions
DRUG
No Results Yet
NCT07115381 | NOT_YET_RECRUITING | NA
66 Participants

A Study on the Intervention Effect of Therapeutic Horticulture Based on the Healing System on Non-suicidal Self-injury in Adolescent Patients With Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-02-28
Completion: 2026-12-31
Conditions
Depression
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07111299 | RECRUITING | NA
100 Participants

Clinical Evaluation of a Nutraceutical Supplement for Hair Growth, Hair Loss and Skin Improvement in Human Volunteers Versus Placebo

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-13
Completion: 2026-07-31
Conditions
Early Female Pattern Hair Loss (FPHL)
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07102355 | COMPLETED | NA
46 Participants

Comparative Effectiveness of Dry Cupping and Graston Techniques in Scapulocostal Syndrome.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-10-01
Completion: 2025-01-25
Conditions
Scapulocostal Syndrome
Interventions
OTHER
No Results Yet
NCT07100990 | RECRUITING | PHASE3
382 Participants

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-11
Completion: 2029-04-01
Conditions
Optic Neuritis Myelitis Myelitis, Transverse
Interventions
DRUG
No Results Yet
NCT07098611 | RECRUITING
470 Participants

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-06-15
Completion: 2025-12-30
Conditions
Ventilator Weaning Respiration, Artificial Respiratory Failure Extubation Readiness Extubation Failure Extubation Succeeded Intensive Care Patients Invasively Ventilated Weaning Invasive Mechanical Ventilation
No Results Yet
NCT07093801 | RECRUITING
300 Participants

Observational Study on Lutetium (177Lu) Vipivotide Tetraxetan to Treat Metastatic Castration Resistant Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-30
Completion: 2029-03-30
Conditions
Metastatic Castration Resistant Prostate Cancer
No Results Yet
NCT07089927 | RECRUITING | NA
20 Participants

Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-02
Completion: 2026-07-15
Conditions
Malignant Solid Neoplasm
Interventions
PROCEDURE OTHER
No Results Yet
NCT07084428 | ACTIVE_NOT_RECRUITING
40 Participants

Pancreatic Antibiotic Concentration Evaluation Assessment

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-01-15
Completion: 2026-01-15
Conditions
Acute Pancreatic Fluid Collection Acute Pancreatitis
No Results Yet
NCT07081633 | RECRUITING | PHASE2
114 Participants

Durvalumab and Tremelimumab With Lenvatinib as First-line Treatment in Patients With Unresectable Hepatocellular Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-08-05
Completion: 2026-11-30
Conditions
Hepatocellular Carcinoma
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
NCT07080008 | NOT_YET_RECRUITING | PHASE1
10 Participants

Evaluation of Lumitrace for Visualizing Ureters During Abdominopelvic Surgeries

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-31
Completion: 2026-09-30
Conditions
Ureter Injury
Interventions
DRUG DEVICE
No Results Yet
NCT07079592 | NOT_YET_RECRUITING | NA
8666 Participants

A Deep-Learning-Enabled Electrocardiogram for Detecting Pulmonary Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-31
Completion: 2026-06-15
Conditions
Artificial Intelligence (AI) Artificial Intelligence (AI) in Diagnosis Hypertension, Pulmonary
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07078201 | RECRUITING | PHASE4
40 Participants

Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and Fentanyl

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-01
Completion: 2025-07-15
Conditions
Spinal Anesthesia Duration
Interventions
DRUG
No Results Yet
NCT07075952 | RECRUITING | NA
113 Participants

Training App for Inhibitory Control Towards Food

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-01
Completion: 2026-03-31
Conditions
Obesity &Amp; Overweight Bulimia Nervosa Binge-Eating Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT07073365 | RECRUITING | PHASE2
70 Participants

Bolstering Outcomes After Induction With Osimertinib Plus Chemotherapy Through Optimized Site-Directed Primary Tumor Therapy (BOOST Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-01
Completion: 2030-06-30
Conditions
Non-Small Cell Lung Cancer Epidermal Growth Factor Receptor
Interventions
OTHER
No Results Yet
NCT07070219 | RECRUITING | PHASE1/PHASE2
54 Participants

A Study of CTD402 in T-ALL/LBL Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-07
Completion: 2028-09-30
Conditions
Acute Lymphocytic Leukemia Refractory Lymphoma, Lymphoblastic
Interventions
DRUG
No Results Yet
NCT07068165 | RECRUITING | PHASE2/PHASE3
198 Participants

A Randomized Controlled Study of the Efficacy and Safety of Lenalidomide in the Treatment of Active IgG4-related Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-07
Completion: 2028-07-20
Conditions
IgG4 Related Disease
Interventions
DRUG
No Results Yet
NCT07066241 | COMPLETED | NA
50 Participants

Virtual Reality on Stress, Pain Levels in Patients With Hyperthyroidism Undergoing Biopsy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-10
Completion: 2025-12-20
Conditions
Virtual Reality Hyperthyroidism
Interventions
DEVICE
No Results Yet
NCT07061938 | NOT_YET_RECRUITING | PHASE1/PHASE2
30 Participants

Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With IgG4-Related Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-01
Completion: 2027-01-20
Conditions
IgG4 Related Disease
Interventions
DRUG
No Results Yet
NCT07059793 | RECRUITING
250 Participants

MITRIS China Post Market Clinical Follow-up (PMCF) Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-08
Completion: 2028-12-31
Conditions
Mitral Valve Replacement
Interventions
DEVICE
No Results Yet
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