Clinical Trials
Showing trials with last updates posted in 2025.
24
Participants
Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2022-08-03
Completion:
2026-06-30
Conditions
AL Amyloidosis
Interventions
PROCEDURE
DRUG
No Results Yet
46
Participants
Nab-Paclitaxel in Combination With Nivolumab to Treat Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma That Progressed on a PD-1 or PD-L1 Inhibitor
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-09-28
Completion:
2026-06-30
Conditions
Metastatic Head-and-neck Squamous-cell Carcinoma
Interventions
DRUG
No Results Yet
52
Participants
Mosunetuzumab With Lenalidomide Augmentation as First-line Therapy for Follicular and Marginal Zone Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2022-07-14
Completion:
2027-08-31
Conditions
Follicular Lymphoma
Marginal Zone Lymphoma
B-cell Lymphoma
Interventions
DRUG
No Results Yet
1840
Participants
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-05-18
Completion:
2025-09-16
Conditions
Early Alzheimer's Disease
Interventions
DRUG
No Results Yet
345
Participants
Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-03-01
Completion:
2022-06-09
Conditions
Hypercholesterolemia
Interventions
DRUG
No Results Yet
12
Participants
Imaging Performance Assessment of 89Zi-girentuximab (89Zr-TLX250) PET in Metastatic Triple Negative Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-09-21
Completion:
2023-03-31
Conditions
Triple Negative Breast Cancer
Interventions
DRUG
187
Participants
Study of the Kinetics of COVID-19 Antibodies for 24 Months in Patients With Confirmed SARS-CoV-2 Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-08-27
Completion:
2022-03-07
Conditions
Covid19
SARS-CoV-2
Interventions
OTHER
No Results Yet
314
Participants
Randomized, Multicenter, Phase III Trial to Assess Conformal Post-operative Radiotherapy vs. Surveillance After Complete Resection of Stage II/III Thymoma (RADIO-RYTHMIC-01)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2024-12-28
Completion:
2031-12-28
Conditions
Thymoma Malignant Recurrent
Interventions
OTHER
No Results Yet
486
Participants
Impact of Left Bundle Branch Area Pacing vs. Right Ventricular Pacing in Atrioventricular Block (LEAP-Block)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-11-13
Completion:
2025-06-30
Conditions
Atrioventricular Block
Left Bundle Branch Area Pacing
Right Ventricular Pacing
Heart Failure
Interventions
DEVICE
No Results Yet
250
Participants
To Assess the Efficacy and Safety of SCD-044 in the Treatment of Moderate to Severe Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-07-30
Completion:
2024-11-11
Conditions
Dermatitis, Atopic
Interventions
DRUG
51
Participants
Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor in Patients With Advanced Solid Tumor
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-11-18
Completion:
2025-12-23
Conditions
Solid Tumor
Advanced Cancer
Metastatic Cancer
Interventions
DRUG
No Results Yet
687
Participants
A Study to Evaluate Camrelizumab Plus Rivoceranib (Apatinib) as Adjuvant Therapy in Patients With Hepatocellular Carcinoma (HCC) at High Risk of Recurrence After Curative Resection or Ablation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-04-01
Completion:
2026-07-31
Conditions
Hepatocellular Carcinoma (HCC)
Interventions
DRUG
No Results Yet
498
Participants
A Study to Assess Contraceptive Efficacy and Safety of Etonogestrel (ENG) Implant Beyond 3 Years of Use (MK-8415-060)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-11-19
Completion:
2024-12-30
Conditions
Contraception
Interventions
COMBINATION_PRODUCT
No Results Yet
260
Participants
Assessing a ctDNA and PET-oriented Therapy in Patients With DLBCL A Multicenter, Open-label, Phase II Trial.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-06-25
Completion:
2026-07-30
Conditions
Diffuse Large B-cell Lymphoma
Interventions
DRUG
No Results Yet
360
Participants
To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-10-05
Completion:
2032-12-31
Conditions
Prostate Carcinoma
Interventions
DRUG
OTHER
No Results Yet
20
Participants
A Clinical Trial to Evaluate the Safety of agenT-797 in COVID-19 Participants With ARDS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-09-21
Completion:
2023-04-23
Conditions
Respiratory Distress Syndrome, Adult
Interventions
DRUG
No Results Yet
124
Participants
Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-10-29
Completion:
2023-08-09
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
DRUG
30
Participants
Protein Requirements for Active Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-08-16
Completion:
2026-06-30
Conditions
Healthy
Interventions
DIETARY_SUPPLEMENT
No Results Yet
384
Participants
Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-11-13
Completion:
2023-09-29
Conditions
ALS
Interventions
DRUG
82
Participants
A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-11-12
Completion:
2024-05-09
Conditions
Peripheral T-cell Lymphoma
Interventions
DRUG
1450
Participants
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-02-24
Completion:
2027-12-31
Conditions
Plasma Cell Myeloma
RISS Stage I Plasma Cell Myeloma
RISS Stage II Plasma Cell Myeloma
Interventions
DRUG
BIOLOGICAL
OTHER
No Results Yet
135
Participants
Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2019-06-25
Completion:
2022-09-07
Conditions
Head and Neck Squamous Cell Carcinoma
Non Small Cell Lung Cancer
Melanoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
27
Participants
Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-03-01
Completion:
2026-06-30
Conditions
Prostate Carcinoma
Interventions
DRUG
OTHER
No Results Yet
30
Participants
Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood & Primary Tumor in ER+/HER2- MBC
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2019-10-11
Completion:
2022-02-08
Conditions
Breast Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
1800
Participants
Creating Peace: Community-based Youth Violence Prevention to Address Racism and Discrimination
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-12-04
Completion:
2026-01-23
Conditions
Adolescent Behavior
Group, Peer
Violence, Non-accidental
Violence, Sexual
Violence, Domestic
Emotional Abuse
Coping Skills
Communication, Personal
Interventions
BEHAVIORAL
No Results Yet
32
Participants
Early Verticalization of the Patient With Acute Respiratory Distress Syndrome: Assessment of Feasibility and Safety.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-10-15
Completion:
2026-07-14
Conditions
Acute Respiratory Distress Syndrome
Prone Position
Interventions
PROCEDURE
No Results Yet
61
Participants
Cancer and Blood Pressure Management, CARISMA Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-10-29
Completion:
2026-08-31
Conditions
Cardiovascular Disorder
Chronic Kidney Disease
Metastatic Renal Cell Carcinoma
Metastatic Thyroid Gland Medullary Carcinoma
Stage IV Renal Cell Cancer AJCC v8
Stage IV Thyroid Gland Medullary Carcinoma AJCC v8
Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8
Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8
Stage IVC Thyroid Gland Medullary Carcinoma AJCC v8
Interventions
OTHER
No Results Yet
62
Participants
Study to Learn More About the Safety of Drug Jivi Over a Long Period of Time in Previously Treated Patients With Hemophilia A (Bleeding Disorder Resulting From a Lack of FVIII) Who Are Receiving Jivi Regularly at Their Treating Doctors to Prevent Bleeding
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2021-05-14
Completion:
2028-06-30
Conditions
Hemophilia A
Interventions
DRUG
No Results Yet
40
Participants
The Effect of Adding Smartphone-based Platform to the Bariatric Surgery Preparation Process
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-12-28
Completion:
2022-10-01
Conditions
Bariatric Surgery Candidate
Nutritional and Metabolic Diseases
Interventions
OTHER
No Results Yet
18
Participants
Implementation of Family Psychosocial Risk Assessment in Pediatric Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-01-01
Completion:
2026-12-31
Conditions
Pediatric Cancer
Interventions
BEHAVIORAL
No Results Yet
195
Participants
Immunization With IMM-101 vs Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-10-01
Completion:
2024-05-07
Conditions
Cancer
Covid-19
Interventions
BIOLOGICAL
OTHER
No Results Yet
76
Participants
Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Diffuse Cutaneous Systemic Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-02-05
Completion:
2024-01-17
Conditions
Diffuse Cutaneous Systemic Sclerosis
Interventions
DRUG
10
Participants
Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Ischemic Stroke
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-12-02
Completion:
2026-02-28
Conditions
Acute Stroke
Interventions
BIOLOGICAL
No Results Yet
30
Participants
Effect of Micropulse Laser on Dry Eye Disease Due to Meibomian Gland Dysfunction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2022-12-06
Completion:
2025-04-03
Conditions
Dry Eye
Dry Eye Syndromes
Meibomian Gland Dysfunction
Interventions
PROCEDURE
DEVICE
No Results Yet
804
Participants
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-10-08
Completion:
2032-12-31
Conditions
Biochemically Recurrent Prostate Carcinoma
Metastatic Prostate Carcinoma
Prostate Adenocarcinoma
Stage IVB Prostate Cancer AJCC v8
Interventions
RADIATION
DRUG
PROCEDURE
OTHER
No Results Yet
1102
Participants
Patients and Health Staff of Cancer Centres During the Covid-19 Pandemic
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-06-15
Completion:
2022-06-28
Conditions
COVID-19
Interventions
DIAGNOSTIC_TEST
500
Participants
B3 for NMD: Bench to Bedside and Back
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2019-05-06
Completion:
2031-12-31
Conditions
Neuromuscular Disease
Interventions
OTHER
No Results Yet
3320
Participants
Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2021-05-12
Completion:
2026-09-30
Conditions
Coronary Artery Disease
Percutaneous Coronary Intervention
Acute Coronary Syndrome
Myocardial Infarction
Interventions
DRUG
No Results Yet
184
Participants
Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-06-01
Completion:
2021-12-14
Conditions
EPP
XLP
Interventions
DRUG
22000
Participants
A Phone-call With a Student/General Practitioner Team to Impact Morbidity of Chronic Patients During COVID-19 Containment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2020-04-30
Completion:
2020-06-30
Conditions
Cardiovascular Diseases
Mental Disorder
Interventions
BEHAVIORAL
No Results Yet
Showing 40 trials per page