Clinical Trials
56
Participants
A Study to Assess the Experimental Malaria Vaccines R78C and RH5.1 Combined With R21/Matrix-M (a "Multi-stage" Malaria Vaccine)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-09-15
Completion:
2026-10-31
Conditions
Malaria,Falciparum
Interventions
BIOLOGICAL
No Results Yet
60
Participants
Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-01-14
Completion:
2028-08-31
Conditions
Prostate Cancer
Prostate Cancer (Adenocarcinoma)
Prostate Cancer Metastatic Disease
Prostate Cancer Recurrent
Prostate Carcinoma
Prostate Neoplasm
Prostate Adenocarcinoma
Prostate Cancer With Bone Metastasis
Vasomotor Disturbance
Vasomotor Symptoms
Vasomotor Symptoms (VMS)
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Vasomotor Symptoms; Hot Flashes
Androgen Deprivation Therapy
Androgen Ablative Therapy of Advanced Hormone-dependent Prostate Carcinoma
Androgen-deprivation Therapy
Hot Flashes
Hot Flushes
Hot Flushes and/or Sweats
Interventions
DRUG
No Results Yet
147
Participants
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-09
Completion:
2026-11-16
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
244
Participants
Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-03-18
Completion:
2028-05-15
Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE
DRUG
RADIATION
No Results Yet
130
Participants
A Study to Assess Adverse Events and Change in Disease Activity of Oral ABBV-453 Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-07-23
Completion:
2030-12-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
75
Participants
A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-01
Completion:
2027-05-31
Conditions
Solid Tumor
Advanced Solid Tumor
Metastatic Solid Tumor
Immune Sensitive Tumor
Interventions
BIOLOGICAL
No Results Yet
34
Participants
iNO300 Therapy in Critically Ill Patients With Pneumonia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-01-31
Completion:
2026-12-31
Conditions
Critical Illness
Pneumonia
Interventions
DRUG
OTHER
No Results Yet
60
Participants
Dual Task and Upper Extremity Performance in Children With Myelomeningocele
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-26
Completion:
2025-12-01
Conditions
Meningomyelocele
Interventions
DIAGNOSTIC_TEST
No Results Yet
36
Participants
HER2 Vaccine for Locally Advanced Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-03-31
Completion:
2029-12-31
Conditions
Breast Cancer
HER2-positive Breast Cancer
Interventions
DRUG
No Results Yet
300
Participants
Deciphering the Genetic Architecture of Autoimmune Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2030-04-22
Conditions
Autoimmune Diseases
No Results Yet
30
Participants
Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2028-07-14
Conditions
Lung Transplantation
Interventions
DRUG
No Results Yet
80
Participants
Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-01-29
Completion:
2026-02-28
Conditions
Recurrent Multiple Myeloma
Refractory Multiple Myeloma
Interventions
PROCEDURE
DRUG
No Results Yet
59
Participants
A Study to Assess the Bioavailability of Risankizumab Following Subcutaneous Administration With Prefilled Pen Relative to a Prefilled Syringe in Healthy Adult Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-08
Completion:
2025-11-25
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
47
Participants
A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-10-22
Completion:
2030-10-01
Conditions
HLA-A*0201 Positive Cells Present
Clear Cell Sarcoma (CCS)
Interventions
DRUG
No Results Yet
8
Participants
Effects of Calcium on Gut Functions and Blood Glucose in Humans With Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-22
Completion:
2026-03-28
Conditions
T2DM
Interventions
OTHER
No Results Yet
30
Participants
VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) Catheters
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2026-12-01
Conditions
Ventricular Arrhythmia
Interventions
DEVICE
No Results Yet
454
Participants
A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-08
Completion:
2027-05-31
Conditions
Immunoglobulin A Nephropathy (IgAN)
Interventions
DRUG
No Results Yet
60
Participants
Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-04-07
Completion:
2028-04-30
Conditions
Glioblastoma
Gliosarcoma
Interventions
DRUG
RADIATION
No Results Yet
33
Participants
Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-04-29
Completion:
2029-05-30
Conditions
T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Interventions
BIOLOGICAL
No Results Yet
24
Participants
A Study on the Safety, Tolerability, Bioavailability and Mechanism of Action of Intravenous NAV-240 in Adults.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-20
Completion:
2025-11-20
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
60
Participants
Why Calories Are Not the Same - a Gut Explanation?
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-15
Completion:
2026-12-31
Conditions
Diet, Healthy
Breath Analysis
Interventions
OTHER
No Results Yet
119
Participants
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-26
Completion:
2028-06-30
Conditions
Acromegaly
Interventions
DRUG
No Results Yet
56
Participants
A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-01
Completion:
2026-05-31
Conditions
Sickle Cell Disease
Interventions
DRUG
No Results Yet
12
Participants
Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological Involvement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2030-12-14
Conditions
Kohlmeier-Degos Disease
Malignant Atrophic Papulosis
Degos Disease
Papulosis, Malignant Atrophic
Interventions
DRUG
No Results Yet
162
Participants
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MyeloMATCH Treatment Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-02-18
Completion:
2027-11-25
Conditions
Core Binding Factor Acute Myeloid Leukemia
Interventions
PROCEDURE
DRUG
No Results Yet
86
Participants
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2029-04-30
Conditions
Malignancy, Hematologic
Neoplasms, Hematologic
Neoplasms, Hematopoietic
Blood Cancer
Hematological Neoplasms
Hematopoietic Malignancies
Dysmyelopoietic Syndromes
Hematopoetic Myelodysplasia
Myeloid Leukemia, Acute
Nonlymphoblastic Leukemia, Acute
Leukemia, Lymphocytic, Acute
Interventions
DRUG
BIOLOGICAL
DEVICE
No Results Yet
20
Participants
Acceptability and Feasibility of a Stress Prevention Program Based on Meditation and Acceptance and Commitment Therapy for Staff at a Cancer Center
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-03-13
Completion:
2025-04-30
Conditions
Employees at a Hospital
Interventions
OTHER
DIAGNOSTIC_TEST
No Results Yet
48
Participants
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-07-19
Completion:
2029-06-02
Conditions
Locally Advanced Adrenal Cortical Carcinoma
Metastatic Adrenal Cortical Carcinoma
Recurrent Adrenal Cortical Carcinoma
Stage III Adrenal Cortical Carcinoma AJCC v8
Stage IV Adrenal Cortical Carcinoma AJCC v8
Unresectable Adrenal Cortical Carcinoma
Interventions
PROCEDURE
DRUG
BIOLOGICAL
No Results Yet
135
Participants
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-08-07
Completion:
2036-03-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
24
Participants
Fiber Smoothie Supplement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-01-31
Completion:
2027-01-01
Conditions
Total Knee Arthroplasty Revision
Inflammatory Markers
Gut Microbiota
Interventions
DIETARY_SUPPLEMENT
No Results Yet
700
Participants
Conquering Hypertension in Urban Vietnam
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-01
Completion:
2029-02-28
Conditions
Hypertension
Interventions
BEHAVIORAL
No Results Yet
50
Participants
A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-07-09
Completion:
2026-01-31
Conditions
Phosphomannomutase 2 Deficiency
PMM2-CDG
Interventions
DRUG
No Results Yet
140
Participants
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-21
Completion:
2030-02-28
Conditions
Epithelial Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Cancer
Neoadjuvant
Interventions
DRUG
No Results Yet
30
Participants
Testing an Anti-cancer Radio-Active Immunotherapy Called Lintuzumab Ac225 in Patients With High-Risk Myelodysplastic Syndrome That Has Not Responded to Other Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-04-27
Completion:
2027-12-31
Conditions
Refractory Myelodysplastic Syndrome
Interventions
RADIATION
PROCEDURE
No Results Yet
20
Participants
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-11-05
Completion:
2027-05-03
Conditions
Moderate to Severe Plaque Psoriasis
Psoriatic Arthritis
Axial Spondyloarthritis
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
530
Participants
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-17
Completion:
2028-09-30
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
30
Participants
Adaptation of Human Brown Adipose Tissue to Calorie Restriction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-01-25
Completion:
2025-12-31
Conditions
Obesity and Overweight
Interventions
BEHAVIORAL
No Results Yet
54
Participants
Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2033-01-01
Conditions
Multiple Myeloma
Relapsed and/or Refractory Multiple Myeloma (RRMM)
Interventions
DRUG
No Results Yet
90
Participants
A Study of LY3549492 in Japanese Participants With Type 2 Diabetes Mellitus (T2D) and Healthy Japanese Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-07
Completion:
2026-02-28
Conditions
Healthy
Type 2 Diabetes Mellitus (T2D)
Interventions
DRUG
No Results Yet
35
Participants
Phase I Trial of High-Density Theta Burst Stimulation (hdTBS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2028-01-13
Conditions
Healthy Volunteers
Interventions
DEVICE
No Results Yet
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