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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06549985 | RECRUITING | NA
60 Participants

Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-17
Completion: 2027-09-30
Conditions
Endometriosis Pelvic Pain
Interventions
BEHAVIORAL
No Results Yet
NCT06533813 | RECRUITING
617 Participants

Clinical Epidemiology in Contemporary Patients With Myelofibrosis.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-14
Completion: 2025-12-19
Conditions
Myelofibrosis
No Results Yet
NCT06530849 | RECRUITING | PHASE1
18 Participants

A Study of GC012F Injection in Subjects With Refractory Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-08-22
Completion: 2027-02-01
Conditions
Refractory Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT06528431 | RECRUITING | PHASE4
180 Participants

Design and Evaluation of an Individualized Biodrug Tapering Strategy Based on Biodrug Dosage: the MONITORA Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-19
Completion: 2026-09-19
Conditions
Arthritis, Rheumatoid
Interventions
DRUG
No Results Yet
NCT06527846 | ACTIVE_NOT_RECRUITING
1027 Participants

Post Marketing Surveillance of JARDIANCE in Chronic Kidney Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-22
Completion: 2027-05-31
Conditions
Kidney Disease, Chronic
Interventions
DRUG
No Results Yet
NCT06526364 | RECRUITING
100 Participants

Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-10
Completion: 2029-06-30
Conditions
Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Secondary Progressive
Interventions
OTHER
No Results Yet
NCT06524544 | RECRUITING | PHASE3
320 Participants

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-02
Completion: 2028-12-31
Conditions
Locally Advanced Urothelial Carcinoma Metastatic Urothelial Carcinoma Unresectable Urothelial Carcinoma
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER
No Results Yet
NCT06521346 | COMPLETED | NA
120 Participants

Active Cycle Breathing Technique (ACBT) on Respiratory Parameters, Dyspnea Related Kinesiophobia and Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-01
Completion: 2025-07-01
Conditions
Respiratory Complication Cardiac Disease
Interventions
PROCEDURE
No Results Yet
NCT06519175 | RECRUITING
1000 Participants

Study of Infantile Lower Limb Malformations and Deformities

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-31
Completion: 2028-05-31
Conditions
Deformity of Limb
Interventions
OTHER PROCEDURE
No Results Yet
NCT06514261 | RECRUITING | PHASE1
45 Participants

Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-18
Completion: 2026-09-16
Conditions
Acute Myeloid Leukemia
Interventions
DRUG PROCEDURE
No Results Yet
NCT06507748 | NOT_YET_RECRUITING | NA
70 Participants

A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2026-05-01
Conditions
Neurofibromatosis Type 1
Interventions
DEVICE
No Results Yet
NCT06506084 | ACTIVE_NOT_RECRUITING
319 Participants

Observational Study on the Use of Ropeginterferon Alfa-2b in Polycythemia Vera (ROPEG-PV)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-08
Completion: 2026-09-30
Conditions
Polycythemia Vera
Interventions
DRUG
No Results Yet
NCT06504290 | RECRUITING | PHASE1
40 Participants

Evaluating Safety, Tolerability and Pharmacokinetic of Multiple Ascending Doses of VV119

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-07-16
Completion: 2026-04-01
Conditions
Schizophrenia
Interventions
DRUG
No Results Yet
NCT06502964 | RECRUITING | PHASE2
82 Participants

Study of ALTO-101 in Patients With Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-11
Completion: 2026-02-28
Conditions
Schizophrenia Cognitive Impairment
Interventions
DRUG DEVICE
No Results Yet
NCT06498635 | RECRUITING | PHASE3
306 Participants

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-01
Completion: 2039-07-15
Conditions
Lung Non-Small Cell Carcinoma Stage II Lung Cancer AJCC v8 Stage IIIA Lung Cancer AJCC v8 Stage IIIB Lung Cancer AJCC v8
Interventions
PROCEDURE BIOLOGICAL OTHER
No Results Yet
NCT06490757 | RECRUITING | PHASE2
25 Participants

A Phase 2 Open-label Single-arm Trial of JAK1 Inhibitor for the Treatment of Large Inflammatory Hepatocellular Adenomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-10-02
Completion: 2028-09-02
Conditions
Inflammatory Hepatocellular Adenoma
Interventions
DRUG
No Results Yet
NCT06487481 | RECRUITING | PHASE1
32 Participants

Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2030-12-01
Conditions
Adrenocortical Carcinoma (ACC) Recurrent Adrenocortical Carcinoma (ACC) Recurrent Abdominal Adrenocortical Carcinoma (ACC) Carcinoma, Adrenocortical Carcinoma, Adrenal Cortical
Interventions
PROCEDURE RADIATION
No Results Yet
NCT06487338 | COMPLETED | NA
40 Participants

Effect of Low-level Laser Therapy Versus Shock Wave Therapy on Pain and Function in Patients With Chronic Non-specific Low Back Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-08-25
Completion: 2024-10-20
Conditions
Low Back Pain
Interventions
OTHER
No Results Yet
NCT06480006 | COMPLETED
100 Participants

Validity and Reliability of the BETY-Biopsychosocial Questionnaire in Individuals With Coronary Artery Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-10
Completion: 2025-05-08
Conditions
Validity Reliability
No Results Yet
NCT06479837 | RECRUITING
500 Participants

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2043-12-01
Conditions
Staphylococcal Infections
No Results Yet
NCT06479512 | COMPLETED
200 Participants

Caval-aorta Index and Perfusion Index on Predict Hypotension After Spinal Anaesthesia in Elderly

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-07-01
Completion: 2025-04-15
Conditions
Anesthesia, Spinal
Interventions
DEVICE
No Results Yet
NCT06465316 | RECRUITING | PHASE1
26 Participants

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-12-06
Completion: 2026-09-16
Conditions
Recurrent Multiple Myeloma Refractory Multiple Myeloma
Interventions
PROCEDURE DRUG
No Results Yet
NCT06461897 | RECRUITING | PHASE3
675 Participants

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-08-19
Completion: 2030-07-31
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06439836 | RECRUITING | PHASE1
27 Participants

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-05
Completion: 2027-06-01
Conditions
Metastatic Urothelial Carcinoma Unresectable Urothelial Carcinoma
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT06438133 | COMPLETED
52 Participants

Digital Supported Compression Bandaging in Patients With Chronic Edema in the Lower Limbs

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-10
Completion: 2025-12-18
Conditions
Compression; Vein Venous Insufficiency Lymphedema of Leg Digital Technology
Interventions
OTHER
No Results Yet
NCT06438107 | NOT_YET_RECRUITING
24 Participants

Deep Phenotyping of the Renal Allograft to Prognosticate Clinical Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2026-04-30
Completion: 2027-12-31
Conditions
Renal Transplant Rejection
No Results Yet
NCT06430801 | RECRUITING | PHASE3
1200 Participants

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-05
Completion: 2028-10-30
Conditions
Crohn's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06429033 | COMPLETED | PHASE1
8 Participants

Purified Exosome Product (PEP) Injected Into the Hypodermis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-14
Completion: 2025-12-17
Conditions
Safety
Interventions
DRUG
No Results Yet
NCT06428396 | RECRUITING | PHASE2
120 Participants

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-11-27
Completion: 2027-05-05
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT06422806 | RECRUITING | PHASE3
365 Participants

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-09-11
Completion: 2026-06-30
Conditions
Metastatic Dedifferentiated Liposarcoma Metastatic Undifferentiated Pleomorphic Sarcoma Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Unresectable Dedifferentiated Liposarcoma Unresectable Undifferentiated Pleomorphic Sarcoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06414889 | RECRUITING | PHASE1
4 Participants

Protocol Title: Safety and Feasibility of Autologous CD34+ Hematopoietic Stem Cells Mobilization and Apheresis in Participants With RUNX1 Familial Platelet Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-05-20
Completion: 2027-06-30
Conditions
RUNX1 Familial Platelet Disorder
Interventions
DRUG PROCEDURE
No Results Yet
NCT06406465 | RECRUITING | PHASE2
60 Participants

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2027-07-30
Conditions
Carcinoma, Neuroendocrine Tumor, Neuroendocrine Tumors, Neuroendocrine Neuroendocrine; Carcinoma Small Cell; Receptors
Interventions
DRUG
No Results Yet
NCT06405932 | COMPLETED | NA
1691 Participants

Study of the Intervention Effect of Self-help Training Camps in Promoting Mental Health Among Perinatal Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-09-11
Completion: 2025-09-01
Conditions
Mental Health Perinatal Depression
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT06397144 | WITHDRAWN | PHASE1
0 Participants

A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-15
Completion: 2025-12-09
Conditions
Biological Availability Healthy Participants
Interventions
DRUG
No Results Yet
NCT06395753 | RECRUITING | PHASE2
66 Participants

A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-05-23
Completion: 2026-12-31
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06395441 | RECRUITING | PHASE3
160 Participants

Wisconsin Ginseng for Decreasing Cancer Related Fatigue

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-08-01
Completion: 2026-11-30
Conditions
Malignant Solid Neoplasm
Interventions
DIETARY_SUPPLEMENT DRUG OTHER
No Results Yet
NCT06394739 | RECRUITING
100 Participants

RevCore for In Stent Thrombosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2024-09-09
Completion: 2025-12-31
Conditions
In-stent Thrombosis
Interventions
DEVICE
No Results Yet
NCT06391775 | TERMINATED | PHASE1/PHASE2
21 Participants

Trial to Assess the Safety and Preliminary Efficacy of GEN1055 on Malignant Solid Tumors as Monotherapy and as Combination Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-05-14
Completion: 2025-11-20
Conditions
Malignant Solid Tumor
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06388733 | RECRUITING | PHASE3
450 Participants

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-19
Completion: 2027-12-31
Conditions
Glioblastoma GBM Brain Neoplasms, Adult, Malignant Brain Tumor
Interventions
DRUG
No Results Yet
NCT06388148 | RECRUITING | NA
286 Participants

Endovascular Treatment for eXtra-Large Ischemic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-16
Completion: 2026-10-31
Conditions
Stroke, Acute Ischemic
Interventions
DRUG PROCEDURE
No Results Yet
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