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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05591521 | COMPLETED
206 Participants

Evaluation of Pain in the Course of in Vitro Fertilization: the Endalgofiv-2 Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-11-30
Completion: 2024-03-24
Conditions
Infertility
Interventions
OTHER
No Results Yet
NCT05588167 | RECRUITING
100 Participants

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-11-28
Completion: 2026-09-30
Conditions
Niemann-Pick Disease, Type C
No Results Yet
NCT05581121 | RECRUITING | PHASE3
510 Participants

PARa-aOrtic LymphAdenectomy in Locally Advanced Cervical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-20
Completion: 2031-12-31
Conditions
Cervical Carcinoma Adenocarcinoma Adenosquamous Carcinoma
Interventions
OTHER PROCEDURE
No Results Yet
NCT05577143 | RECRUITING
303 Participants

Blood Screening for Adult Colorectal Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-23
Completion: 2026-03-31
Conditions
Cancer Colorectal
No Results Yet
NCT05573893 | RECRUITING
800 Participants

PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-09-12
Completion: 2031-12-31
Conditions
Breast Neoplasms Breast Cancer Neoplasm Metastasis
No Results Yet
NCT05570851 | ENROLLING_BY_INVITATION | NA
138 Participants

Alcohol Cessation Among Head and Neck Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-01
Completion: 2026-03-31
Conditions
Head and Neck Cancer Alcohol Use, Unspecified
Interventions
BEHAVIORAL
No Results Yet
NCT05564390 | RECRUITING | PHASE2
2000 Participants

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-06-18
Completion: 2029-05-15
Conditions
Acute Myeloid Leukemia Myelodysplastic Syndrome
Interventions
PROCEDURE DRUG OTHER RADIATION
No Results Yet
NCT05564377 | RECRUITING | PHASE2
2900 Participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-07
Completion: 2030-07-01
Conditions
Advanced Malignant Solid Neoplasm Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Locally Advanced Malignant Solid Neoplasm Malignant Female Reproductive System Neoplasm Metastatic HER2-Negative Breast Carcinoma Metastatic Malignant Solid Neoplasm Recurrent Endometrial Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Malignant Female Reproductive System Neoplasm Recurrent Malignant Solid Neoplasm Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Unresectable HER2-Negative Breast Carcinoma Unresectable Malignant Solid Neoplasm
Interventions
DRUG PROCEDURE BIOLOGICAL
No Results Yet
NCT05559671 | RECRUITING | PHASE4
224 Participants

Safety of the Herpes Zoster Subunit Vaccine in Lupus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-21
Completion: 2027-07-31
Conditions
Systemic Lupus Erythematosus
Interventions
BIOLOGICAL
No Results Yet
NCT05554419 | NOT_YET_RECRUITING | PHASE2
184 Participants

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-03-01
Completion: 2026-08-31
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm Acute Myeloid Leukemia Post Cytotoxic Therapy Secondary Acute Myeloid Leukemia
Interventions
DRUG PROCEDURE
No Results Yet
NCT05554406 | RECRUITING | PHASE2
335 Participants

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-09-25
Completion: 2027-03-31
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Acute Myeloid Leukemia Post Cytotoxic Therapy Acute Myeloid Leukemia, Myelodysplasia-Related
Interventions
DRUG PROCEDURE
No Results Yet
NCT05554393 | RECRUITING | PHASE2
153 Participants

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-09-13
Completion: 2027-12-31
Conditions
Acute Myeloid Leukemia
Interventions
DRUG PROCEDURE
No Results Yet
NCT05554380 | SUSPENDED | PHASE2
33 Participants

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-09-22
Completion: 2026-08-31
Conditions
Locally Advanced Malignant Solid Neoplasm Metastatic Malignant Solid Neoplasm Unresectable Malignant Solid Neoplasm
Interventions
PROCEDURE DRUG
No Results Yet
NCT05554328 | RECRUITING | PHASE2
165 Participants

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-25
Completion: 2028-10-01
Conditions
Recurrent Endometrial Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma
Interventions
PROCEDURE DRUG
No Results Yet
NCT05544019 | RECRUITING | PHASE1
52 Participants

Study of SGR-1505 in Mature B-Cell Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-10
Completion: 2026-03-31
Conditions
Mature B-Cell Neoplasm Non Hodgkin Lymphoma DLBCL Waldenstrom Macroglobulinemia MALT Lymphoma Follicular Lymphoma Pediatric-Type Follicular Lymphoma IRF4 Gene Rearrangement EBV-Positive DLBCL, Nos Burkitt Lymphoma Plasmablastic Lymphoma High-grade B-cell Lymphoma Primary Cutaneous Follicle Center Lymphoma Primary Effusion Lymphoma Mantle Cell Lymphoma DLBCL Germinal Center B-Cell Type Primary Mediastinal Large B Cell Lymphoma T-Cell/Histiocyte Rich Lymphoma ALK-Positive Large B-Cell Lymphoma Primary Cutaneous Diffuse Large B-Cell Lymphoma Splenic Marginal Zone Lymphoma Chronic Lymphocytic Leukemia Nodal Marginal Zone Lymphoma HHV8-Positive DLBCL, Nos Lymphoplasmacytic Lymphoma Duodenal-Type Follicular Lymphoma
Interventions
DRUG
No Results Yet
NCT05534399 | NOT_YET_RECRUITING | NA
526 Participants

Antibiotic Strategy and Asymptomatic Bacteriuria in the Context of Intra-vesical Botulinum Toxin A Injections.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-05-31
Completion: 2027-03-31
Conditions
Urinary Tract Disease
Interventions
PROCEDURE
No Results Yet
NCT05533645 | RECRUITING | NA
99 Participants

Food Frequency Questionnaire to Assess Sodium Intake

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-06
Completion: 2026-06-30
Conditions
Hypertension Renal Insufficiency
Interventions
OTHER
No Results Yet
NCT05524571 | ACTIVE_NOT_RECRUITING | PHASE3
100 Participants

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-01-05
Completion: 2026-03-31
Conditions
Thyroid Eye Disease
Interventions
DRUG
No Results Yet
NCT05521503 | RECRUITING
400 Participants

Biopsy Collection and Repository Database

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-12-21
Completion: 2030-12-31
Conditions
Cardiovascular Diseases
No Results Yet
NCT05520099 | RECRUITING
416 Participants

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-26
Completion: 2027-01-31
Conditions
Immunotherapy Cancer Bladder Cancer Urothelial Carcinoma Bladder Kidney Cancer Clear Cell Renal Cell Cancer (ccRCC) Colorectal Cancer MSI-H Colorectal Cancer DMMR Colorectal Cancer Head and Neck Cancer (H&N) Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) Liver Cancer Hepatocellular Carcinoma (HCC) Lung Cancer (NSCLC) NSCLC (Non-small Cell Lung Cancer) Skin Cancer Cutaneous Melanoma Endometrial Cancer Solid Tumor Cancer
Interventions
PROCEDURE
No Results Yet
NCT05499884 | COMPLETED | NA
10 Participants

Feasibility and Potential Aids of Intra-operative Endo-vaginal Ultrasound When Performing Rectal Shaving for Endometriosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-03
Completion: 2024-07-15
Conditions
Endometriosis
Interventions
PROCEDURE
No Results Yet
NCT05494632 | COMPLETED | NA
45 Participants

Interaural Frequency and Loudness Mismatch in SSD CI Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-12
Completion: 2024-07-30
Conditions
Outcomes
Interventions
DEVICE
Results Available
NCT05491018 | NOT_YET_RECRUITING
13270 Participants

Performance for French Pediatric Intensive Care Units

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-31
Completion: 2027-10-31
Conditions
Severity of Illness Index
No Results Yet
NCT05490446 | ACTIVE_NOT_RECRUITING | PHASE2
87 Participants

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-11-07
Completion: 2026-03-31
Conditions
Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT05484141 | NOT_YET_RECRUITING | NA
34 Participants

The Effect of Blood Flow Restriction Method in Patellar Instability

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-01
Completion: 2026-12-01
Conditions
Patellar Abnormality
Interventions
OTHER
No Results Yet
NCT05480449 | RECRUITING | PHASE1/PHASE2
89 Participants

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-20
Completion: 2027-09-20
Conditions
B Cell Acute Lymphoblastic Leukemia (B-ALL) B Lineage Lymphoblastic Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT05477953 | NOT_YET_RECRUITING
50 Participants

An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About the Risk of Pregnancy Complications and About the Mother's and Baby's Health

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2026-06-30
Completion: 2032-01-31
Conditions
Chagas Disease
Interventions
DRUG
No Results Yet
NCT05473429 | RECRUITING | NA
215 Participants

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2026-10-06
Conditions
Intellectual Disability
Interventions
DEVICE
No Results Yet
NCT05468502 | COMPLETED | PHASE1
17 Participants

Phase I/IIa Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection in the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-10-10
Completion: 2025-08-01
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT05465941 | RECRUITING | PHASE2
43 Participants

PLX038 for Treatment of Metastatic Platinum-resistant Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-14
Completion: 2027-05-15
Conditions
Platinum-Resistant Fallopian Tube Carcinoma Platinum-Resistant Ovarian Carcinoma Platinum-Resistant Primary Peritoneal Carcinoma Stage IV Fallopian Tube Cancer AJCC v8 Stage IV Ovarian Cancer AJCC v8 Stage IV Primary Peritoneal Cancer AJCC v8
Interventions
PROCEDURE DRUG
No Results Yet
NCT05464758 | COMPLETED | NA
16 Participants

The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-01
Completion: 2024-09-13
Conditions
Cold Exposure
Interventions
OTHER
No Results Yet
NCT05458960 | TERMINATED | NA
3 Participants

Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rate

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-28
Completion: 2025-08-28
Conditions
Cervical Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05457166 | RECRUITING | NA
40 Participants

Use of the KASPARD System for Fall Prevention in Nursing Homes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-07-07
Completion: 2026-10-31
Conditions
Accidental Falls Nursing Homes
Interventions
DEVICE
No Results Yet
NCT05455359 | RECRUITING | PHASE4
120 Participants

Gastrointestinal Dysmotility on Aspiration Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-13
Completion: 2027-05-31
Conditions
Esophageal Motility Disorders Gastric Motor Dysfunction Aspiration Pneumonia Gastro Esophageal Reflux
Interventions
DRUG
No Results Yet
NCT05454657 | COMPLETED | NA
120 Participants

Heart Rate Variability Biofeedback for Substance Use Disorder: A Randomized Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-01-04
Completion: 2024-09-15
Conditions
Substance Use Disorders
Interventions
DEVICE BEHAVIORAL
Results Available
NCT05454475 | COMPLETED
270 Participants

Effect of Different Water Injection Temperatures on the Safety and Comfort of Patients Undergoing Ultrasound Endoscopy of Small Probes Under Intravenous Anesthesia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-06-14
Completion: 2023-05-01
Conditions
Small Probe Ultrasound Endoscopy The Water Temperature
Interventions
OTHER
No Results Yet
NCT05454202 | COMPLETED
20 Participants

Assessment of the Interest of ANI in the Non-communicating Patient in Palliative Care

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-22
Completion: 2024-05-24
Conditions
End of Life Pain Analgesia
Interventions
DEVICE
No Results Yet
NCT05447078 | COMPLETED | PHASE3
492 Participants

Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-07-01
Completion: 2025-12-08
Conditions
Healthy Volunteers
Interventions
DRUG DIETARY_SUPPLEMENT
No Results Yet
NCT05432804 | SUSPENDED | PHASE1/PHASE2
97 Participants

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-20
Completion: 2027-06-30
Conditions
MGMT-Methylated Glioblastoma Recurrent Glioblastoma, IDH-Wildtype Recurrent MGMT-Methylated Glioblastoma
Interventions
PROCEDURE DRUG
No Results Yet
NCT05413304 | RECRUITING | PHASE1
17 Participants

Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-07
Completion: 2025-12-31
Conditions
Glioma
Interventions
DRUG DEVICE
No Results Yet
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