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Clinical Trials

Showing trials with last updates posted in 2025.

NCT04324944 | COMPLETED | NA
39 Participants

Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-07-05
Completion: 2025-09-13
Conditions
Schizophrenia Schizoaffective Disorder Delusional Disorder Major Depressive Disorder With Psychotic Features
Interventions
BEHAVIORAL
No Results Yet
NCT04319939 | COMPLETED
66 Participants

Diaphragm Ultrasound Measurements With Variations in Modes of Ventilation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-05
Completion: 2022-04-11
Conditions
Mechanical Ventilation
Interventions
OTHER
No Results Yet
NCT04316546 | RECRUITING | PHASE2
45 Participants

MK-7075 (Miransertib) in Proteus Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-05-20
Completion: 2026-07-01
Conditions
Proteus Syndrome
Interventions
DRUG
No Results Yet
NCT04296305 | ACTIVE_NOT_RECRUITING | PHASE4
84 Participants

Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-09-10
Completion: 2027-12-31
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
DRUG OTHER
No Results Yet
NCT04278313 | RECRUITING | NA
90 Participants

Ovarian Function Following Intraovarian Injection of PRP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-24
Completion: 2026-07-31
Conditions
Diminished Ovarian Reserve Diminished Ovarian Reserve Due to Advanced Maternal Age
Interventions
PROCEDURE
No Results Yet
NCT04267848 | RECRUITING | PHASE3
1210 Participants

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-06-16
Completion: 2025-12-15
Conditions
Lung Non-Small Cell Carcinoma Lung Non-Small Cell Squamous Carcinoma Lung Non-Squamous Non-Small Cell Carcinoma Stage II Lung Cancer AJCC v8 Stage IIIA Lung Cancer AJCC v8 Stage IIIB Lung Cancer AJCC v8
Interventions
PROCEDURE DRUG OTHER BIOLOGICAL
No Results Yet
NCT04242563 | COMPLETED | NA
156 Participants

Virtual Reality for Preoperative Anxiety in Interventional Cardiology

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-02
Completion: 2021-07-12
Conditions
Anxiety
Interventions
OTHER
No Results Yet
NCT04200937 | ENROLLING_BY_INVITATION
450 Participants

IT Matters: The Erectile Restoration Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-08-05
Completion: 2031-01-31
Conditions
Erectile Dysfunction
Interventions
DEVICE
No Results Yet
NCT04179448 | ACTIVE_NOT_RECRUITING | NA
22 Participants

A Comparison of Side Access Mucosal Releasing Incision (SAMRI) and Sulcular Tunnel Access to Treat Gingival Recession.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-02-11
Completion: 2023-12-11
Conditions
Gingival Recession Lack of Keratinized Gingiva
Interventions
PROCEDURE
No Results Yet
NCT04165941 | ACTIVE_NOT_RECRUITING | PHASE1
22 Participants

Novel Gamma-Delta (γδ)T Cell Therapy for Treatment of Patients With Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-02-11
Completion: 2026-12-31
Conditions
Brain Tumor Adult
Interventions
BIOLOGICAL
No Results Yet
NCT04155866 | COMPLETED
30 Participants

Comparing the Difference in Muscle Synergies Between Healthy Participants and Chronic Stroke Survivors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-07-01
Completion: 2025-12-01
Conditions
Healthy
Interventions
OTHER
No Results Yet
NCT04154514 | COMPLETED | NA
53 Participants

A Potential Wearable for Post-stroke Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-02-01
Completion: 2025-12-01
Conditions
Chronic Stroke
Interventions
DEVICE
No Results Yet
NCT04151667 | ACTIVE_NOT_RECRUITING | PHASE2
33 Participants

Daratumumab Based Response Adapted Therapy for Older Adults With Newly Diagnosed Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-11-22
Completion: 2023-11-08
Conditions
Multiple Myeloma
Interventions
DRUG
Results Available
NCT04148911 | COMPLETED | PHASE3
184 Participants

A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-12-10
Completion: 2024-12-15
Conditions
Triple-Negative Breast Cancer
Interventions
DRUG
Results Available
NCT04109586 | ACTIVE_NOT_RECRUITING | NA
56 Participants

Diet and Fat Mass After Traumatic Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-09-15
Completion: 2025-12-30
Conditions
Obesity Metabolic Disease Spinal Cord Injuries
Interventions
BEHAVIORAL
No Results Yet
NCT04099368 | COMPLETED | NA
120 Participants

Music Appreciation After Cochlear Implantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-10-01
Completion: 2025-01-01
Conditions
Hearing Loss Cochlear Implants
Interventions
BEHAVIORAL
No Results Yet
NCT04097145 | RECRUITING | NA
870 Participants

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-12-11
Completion: 2027-12-31
Conditions
Tricuspid Regurgitation Tricuspid Valve Insufficiency Tricuspid Valve Disease
Interventions
DEVICE DRUG
No Results Yet
NCT04090957 | COMPLETED | PHASE3
1015 Participants

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort II)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-09-27
Completion: 2022-08-18
Conditions
Vasomotor Symptoms Menopausal Symptoms
Interventions
DRUG
Results Available
NCT04075864 | COMPLETED | NA
3 Participants

Feasibility of a New Model for Exercise Prescription in Cystic Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-12-01
Completion: 2025-12-10
Conditions
Cystic Fibrosis
Interventions
BEHAVIORAL
No Results Yet
NCT04044443 | ACTIVE_NOT_RECRUITING
108 Participants

IMPEDE and IMPEDE-FX Embolization Plug Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2019-07-09
Completion: 2025-08-30
Conditions
Peripheral Vascular Embolization
Interventions
DEVICE
No Results Yet
NCT04041310 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
115 Participants

Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-10-21
Completion: 2026-10-30
Conditions
Solid Tumor, Adult
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT04034264 | RECRUITING
6500 Participants

Febrile Disease Landscape in Cambodia Via Metagenomic Pathogen Sequencing

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2019-07-23
Completion: 2026-07-01
Conditions
Vector-Borne Diseases Emerging Pathogens
No Results Yet
NCT04014348 | RECRUITING
250 Participants

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-10-20
Completion: 2026-12-10
Conditions
Cardiovascular (CV) Risk
No Results Yet
NCT04009005 | ACTIVE_NOT_RECRUITING | NA
44 Participants

Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2020-05-01
Completion: 2022-08-01
Conditions
Clinically Isolated Syndrome Relapsing Remitting Multiple Sclerosis
Interventions
BEHAVIORAL
No Results Yet
NCT03995173 | ACTIVE_NOT_RECRUITING | PHASE2
1 Participants

Pilot rTMS for AUD+mTBI

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-03-21
Completion: 2026-03-31
Conditions
Alcohol Use Disorder Mild Traumatic Brain Injury Post-traumatic Stress Disorder
Interventions
DEVICE
No Results Yet
NCT03993379 | TERMINATED | PHASE2
3 Participants

PROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-11-20
Completion: 2020-05-21
Conditions
Solid Tumor Unresectable or Metastatic Melanoma
Interventions
DRUG
Results Available
NCT03983850 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
105 Participants

Optimizing PTCy Dose and Timing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-07-09
Completion: 2025-11-25
Conditions
Graft Versus Host Disease Hematologic Neoplasms
Interventions
DRUG
No Results Yet
NCT03952598 | SUSPENDED | PHASE2
42 Participants

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-10-16
Completion: 2025-12-31
Conditions
Glioma Gliomas High Grade Glioma Malignant Glioma Low Grade Glioma
Interventions
DRUG DEVICE
No Results Yet
NCT03937830 | ACTIVE_NOT_RECRUITING | PHASE2
27 Participants

Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-03-10
Completion: 2025-12-31
Conditions
Hepatocellular Cancer Hepatocellular Carcinoma Metastatic Hepatocellular Carcinoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT03937804 | COMPLETED
83 Participants

New Approaches for Empowering Studies of Asthma in Populations of African Descent

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2019-09-23
Completion: 2021-07-15
Conditions
Asthma
No Results Yet
NCT03922724 | RECRUITING | PHASE2
330 Participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-04-18
Completion: 2026-10-31
Conditions
Peripheral T-cell Lymphomas Lymphoproliferative Disorders Immune System Diseases
Interventions
DRUG PROCEDURE
No Results Yet
NCT03895567 | SUSPENDED | PHASE1
37 Participants

Study to Compare Blood Levels of Ceftriaxone Given by Suppository or Injection.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-12-31
Completion: 2026-12-31
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT03873610 | ACTIVE_NOT_RECRUITING | NA
200 Participants

Resiliency Training in Adolescents With NF1 and NF2

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-12-15
Completion: 2026-02-20
Conditions
Neurofibromatoses
Interventions
BEHAVIORAL
No Results Yet
NCT03841617 | RECRUITING | PHASE2
30 Participants

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-07-29
Completion: 2035-11-01
Conditions
Thyroid Cancer
Interventions
DRUG RADIATION OTHER
No Results Yet
NCT03825835 | RECRUITING | NA
1200 Participants

30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-06-27
Completion: 2027-09-30
Conditions
Premature Infant Respiratory Distress Syndrome in Premature Infant Neurodevelopmental Outcome
Interventions
DRUG
No Results Yet
NCT03811561 | ACTIVE_NOT_RECRUITING | PHASE3
1500 Participants

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-05-08
Completion: 2026-12-25
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT03762733 | ENROLLING_BY_INVITATION
500 Participants

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-01-04
Completion: 2028-12-29
Conditions
Breast Cancer Ovarian Cancer Uterine Cancer
No Results Yet
NCT03751683 | COMPLETED
29 Participants

Evaluation Genotypic, Phenotypic and Prognosis APECED Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2009-07-30
Completion: 2018-01-25
Conditions
APECED
No Results Yet
NCT03745339 | RECRUITING
150 Participants

Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2019-06-07
Completion: 2026-10-01
Conditions
Opioid-Related Disorders Drug Addiction
No Results Yet
NCT03743649 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
110 Participants

Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2019-07-17
Completion: 2026-02-28
Conditions
Delirium Locally Advanced Malignant Neoplasm Metastatic Malignant Neoplasm Recurrent Malignant Neoplasm
Interventions
DRUG OTHER
No Results Yet
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