Clinical Trials
Showing trials with last updates posted in 2025.
42
Participants
Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-09
Completion:
2028-04-05
Conditions
Hematopoietic and Lymphatic System Neoplasm
Interventions
OTHER
PROCEDURE
DRUG
No Results Yet
3492
Participants
Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-01
Completion:
2029-05-01
Conditions
Opioid Use Disorder
Interventions
OTHER
No Results Yet
6
Participants
A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-15
Completion:
2027-10-01
Conditions
Congenital Erythropoietic Porphyria (CEP)
Interventions
DRUG
No Results Yet
123
Participants
A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia Areata
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-19
Completion:
2029-02-28
Conditions
Alopecia Areata
Interventions
DRUG
No Results Yet
60
Participants
EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-10-01
Completion:
2027-02-28
Conditions
Ureteral Stricture
Interventions
DEVICE
No Results Yet
120
Participants
Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-09-16
Completion:
2026-09-30
Conditions
Pneumothorax
Cardiac Surgery
Lung Ultrasound
Chest Tube Removal
Postoperative Complications (Cardiopulmonary)
No Results Yet
215
Participants
NS-PFA Catheter Ablation of Paroxysmal Atrial Fibrillation With the Pulse Biosciences CellFX System
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-31
Completion:
2026-10-31
Conditions
Atrial Fibrillation Paroxysmal
Cardiac Ablation
Cardiac Arrhythmia
Interventions
DEVICE
No Results Yet
30
Participants
Study of GS-3242 in Participants With HIV-1; Substudy-05
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-29
Completion:
2025-12-31
Conditions
HIV-1-infection
Interventions
DRUG
No Results Yet
75
Participants
A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-27
Completion:
2027-03-30
Conditions
Von Willebrand Disease, Type 3
Interventions
DRUG
No Results Yet
40
Participants
Characterization of Placental Diffusion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-07-06
Completion:
2027-12-31
Conditions
Pregnancy in Diabetic
Placenta Diseases
Interventions
DIAGNOSTIC_TEST
No Results Yet
132
Participants
Effects of Different Irrigation Activation Techniques on the Healing of Large Periapical Lesions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-06-01
Completion:
2024-06-30
Conditions
Periapical Periodontitis
Irrigation Activation
Lasers
Interventions
OTHER
90
Participants
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-09
Completion:
2028-01-31
Conditions
Refractory Rheumatoid Arthritis (RA)
Idiopathic Inflammatory Myopathies (IIMs)
Systemic Sclerosis (SSc)
Rheumatoid Arthritis (RA
IIM
Myositis
Scleroderma
Sjogren Syndrome
Sjogrens Disease
Interventions
DRUG
No Results Yet
40
Participants
Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-02-01
Completion:
2026-10-15
Conditions
Psychiatric Disorder
Interventions
PROCEDURE
OTHER
BEHAVIORAL
No Results Yet
108
Participants
Does the TAP Block Work Better Than the TFP Block for Relieving Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-25
Completion:
2025-12-15
Conditions
Pain
Interventions
PROCEDURE
No Results Yet
365
Participants
Aerodynamic Measurements in the Pediatric Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-22
Completion:
2030-12-31
Conditions
Normal Voice
Interventions
DEVICE
No Results Yet
40
Participants
Prevalence and Description of FIRE (Food Induced Immediate Response of the Esophagus) in the Pediatric Population With Eosinophilic Esophagitis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-01
Completion:
2026-05-01
Conditions
Eosinophilic Esophagitis
No Results Yet
46
Participants
Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-02-01
Completion:
2027-04-01
Conditions
Delirium
Surgery-Complications
Interventions
DRUG
No Results Yet
24
Participants
Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-30
Completion:
2028-05-30
Conditions
Advanced Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma
Recurrent Hepatocellular Carcinoma
Refractory Hepatocellular Carcinoma
Stage III Hepatocellular Carcinoma AJCC v8
Stage IV Hepatocellular Carcinoma AJCC v8
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
150
Participants
Hold me Tight/Let me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-11
Completion:
2028-02-01
Conditions
Parent Training
Parent Child Relationship
Parent-child Problem
Interventions
BEHAVIORAL
No Results Yet
201
Participants
A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-23
Completion:
2026-04-30
Conditions
Healthy
Overweight
Obesity
Type 2 Diabetes
Interventions
DRUG
No Results Yet
666
Participants
Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-09-01
Completion:
2028-09-01
Conditions
Dental Caries
Dental Cavities
Interventions
PROCEDURE
No Results Yet
142
Participants
Integrating SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-24
Completion:
2025-12-18
Conditions
Disease and Dysfunction
Functional Fitness Deterioration
Activities of Daily Living
Instrumental Activities of Daily Living
Sleep Quality
Interventions
OTHER
No Results Yet
680
Participants
Effectiveness of Integrated Network for Student Psychosocial Intervention, Resilience, and Education (INSPIRE) on Mental Health Outcomes Among Indonesian Adolescents in Bandung
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-28
Completion:
2026-02-16
Conditions
Adolescents
Health Knowledge
Mental Health
Health Literacy
Resilience
Depression
Anxiety
Parents
School Intervention
Interventions
BEHAVIORAL
No Results Yet
40
Participants
Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Walking
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-28
Completion:
2025-10-05
Conditions
Cardiovascular Diseases (CVD)
Coronary Heart Disease (CHD)
Heart Failure
Congenital Heart Disease
No Results Yet
142
Participants
Using SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-23
Completion:
2025-12-18
Conditions
Cognitive and Behavioral Impairment
Sensory and Perceptual Impairment
Interventions
OTHER
No Results Yet
30
Participants
Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-01
Completion:
2026-07-31
Conditions
Diabetic Foot Ulcers (DFUs)
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions
DEVICE
OTHER
No Results Yet
20
Participants
Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-29
Completion:
2025-12-31
Conditions
Diabetic Foot Ulcers (DFUs)
Venous Leg Ulcers (VLUs)
Pressure Ulcers
Surgical Wound Dehiscence (SWD)
Chronic Wounds
Undermined and Tunneling Wounds
Interventions
DEVICE
No Results Yet
An Expanded Access Study to Assess Treprostinil Palmitil Inhalation Powder (TPIP) for Participants With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-24
Conditions
Pulmonary Arterial Hypertension
Pulmonary Hypertension, Interstitial Lung Disease
Interventions
DRUG
No Results Yet
16
Participants
Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-31
Completion:
2025-09-19
Conditions
Glucose Metabolism
Glucagon
Interventions
OTHER
No Results Yet
42
Participants
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-09
Completion:
2027-11-30
Conditions
Metabolic Dysfunction-Associated Steatohepatitis
Interventions
DRUG
No Results Yet
92
Participants
FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-05
Completion:
2028-03-31
Conditions
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Interventions
DRUG
No Results Yet
72
Participants
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-01
Completion:
2027-06-22
Conditions
Systemic Lupus Erythematosus
Idiopathic Inflammatory Myopathies
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
60
Participants
Safety of a Single, Intravitreal Injection of 8.8M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-20
Completion:
2026-09-30
Conditions
Retinitis Pigmentosa
Interventions
BIOLOGICAL
OTHER
No Results Yet
6000
Participants
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-23
Completion:
2029-10-31
Conditions
Percutaneous Coronary Intervention
Peripheral Endovascular Intervention
Interventions
DRUG
No Results Yet
100
Participants
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-04
Completion:
2025-08-01
Conditions
Intra-Abdominal Infections
Intestinal Obstruction
Appendicitis Acute
Perforated Viscus
240
Participants
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-28
Completion:
2026-12-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
3375
Participants
Shield Post-Approval Study Protocol
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-14
Completion:
2030-09-01
Conditions
Colo-rectal Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
60
Participants
Evaluation of the Efficacy of Laser Acupuncture on Uremic Pruritus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-04-09
Completion:
2024-05-11
Conditions
Uremia
Interventions
DEVICE
26
Participants
Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-15
Completion:
2028-04-01
Conditions
Recurrent Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia
Interventions
DRUG
PROCEDURE
OTHER
No Results Yet
44
Participants
Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic Urticaria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-22
Completion:
2027-09-01
Conditions
Chronic Urticaria (CU): Chronic Inducible Urticaria (CINDU) and Chronic Spontaneous Urticaria (CSU)
Interventions
DRUG
No Results Yet
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