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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06537934 | RECRUITING
123 Participants

Advanced Mutidimensional and Ultra High Resolution Computed Tomography to Inspect Cardiopulmonary Involvement in Progressive Fibrosing Interstitial Lung Diseases

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-09-01
Completion: 2025-09-01
Conditions
Interstitial Lung Diseases
No Results Yet
NCT06535451 | RECRUITING
1000 Participants

Lung Cancer Screening Program in Mexico

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2022-03-24
Completion: 2026-03-24
Conditions
Lung Cancer
Interventions
OTHER
No Results Yet
NCT06529809 | RECRUITING | PHASE1/PHASE2
50 Participants

Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-11
Completion: 2031-12-31
Conditions
Locally Advanced Cervical Carcinoma
Interventions
RADIATION DRUG
No Results Yet
NCT06526494 | WITHDRAWN | PHASE2
0 Participants

Metformin and Vascular Function in Prediabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-11-13
Completion: 2025-12-01
Conditions
PreDiabetes
Interventions
DRUG OTHER
No Results Yet
NCT06523660 | ACTIVE_NOT_RECRUITING | NA
40 Participants

Improving Executive Function in Korean Children With Autism

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-09-11
Completion: 2026-03-15
Conditions
Autism Spectrum Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06518655 | RECRUITING
3000 Participants

Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-30
Completion: 2026-12-30
Conditions
Pulmonary Nodules, Multiple Pulmonary Nodules, Solitary Lung Cancer
Interventions
OTHER
No Results Yet
NCT06515691 | RECRUITING | NA
60 Participants

Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-01-03
Completion: 2026-02-15
Conditions
Obesity Bariatric Surgery Laparoscopic Sleeve Gastrectomy Acute Post Operative Pain
Interventions
PROCEDURE
No Results Yet
NCT06511895 | COMPLETED | PHASE2
57 Participants

AZD4205 in Relapsed or Refractory Peripheral T Cell Lymphoma (JACKPOT27)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-05-31
Completion: 2025-10-17
Conditions
Peripheral T Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06501118 | RECRUITING | NA
3600 Participants

Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-09-01
Completion: 2026-06-30
Conditions
Respiratory Failure Acute Hypoxemic Respiratory Failure Acute Hypoxic Respiratory Failure Hypoxemia Hypoxia Hypoxic Respiratory Failure
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT06500702 | RECRUITING | PHASE2
84 Participants

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-12-19
Completion: 2026-12-23
Conditions
Focal Segmental Glomerulosclerosis Glomerulonephritis Minimal Lesion
Interventions
DRUG
No Results Yet
NCT06492616 | RECRUITING | PHASE3
4220 Participants

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-09-27
Completion: 2029-08-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT06490991 | COMPLETED | PHASE1
16 Participants

Comparison of HRS-5965 Capsules and Tablets in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-07-17
Completion: 2024-08-06
Conditions
Paroxysmal Nocturnal Hemoglobinuria，IgA Nephropathy
Interventions
DRUG
No Results Yet
NCT06488716 | TERMINATED | PHASE1
12 Participants

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-12-16
Completion: 2025-11-05
Conditions
Solid Tumour
Interventions
DRUG
No Results Yet
NCT06486779 | RECRUITING
160 Participants

Kesimpta (Ofatumumab) in Greek Multiple Sclerosis Patients - an Observational Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-12-10
Completion: 2028-12-30
Conditions
Relapsing Multiple Sclerosis (RMS)
Interventions
OTHER
No Results Yet
NCT06479070 | RECRUITING | NA
188 Participants

Prognostic Value of Measuring CtDNA in a Cohort of Patients With Stage III and IV Upper Aero-digestive Tract (UADT) Cancer , Treated With Curative RADiOtherapy With or Without Concomitant Treatment.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-09-30
Completion: 2026-09-30
Conditions
SCC - Squamous Cell Carcinoma Upper Aero-digestive Tract (UADT) Neoplasm
Interventions
OTHER
No Results Yet
NCT06475963 | COMPLETED
41 Participants

Evaluation of Clinical Outcomes of Scaffold Treatment of Partial Meniscal Injuries of the Knee

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-03-17
Completion: 2025-07-31
Conditions
Knee Osteoarthritis Knee Injuries Meniscus Lesion
Interventions
OTHER
No Results Yet
NCT06470438 | RECRUITING | PHASE1
170 Participants

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-05-28
Completion: 2027-10-29
Conditions
Lymphoma, Non-Hodgkin Refractory B-Cell NHL Relapsed B-cell NHL
Interventions
DRUG
No Results Yet
NCT06468202 | RECRUITING | PHASE4
10742 Participants

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-10-18
Completion: 2029-01-01
Conditions
Hypertensive Disorders of Pregnancy Preeclampsia Gestational Hypertension
Interventions
DRUG
No Results Yet
NCT06465810 | RECRUITING
1850 Participants

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-25
Completion: 2031-12-29
Conditions
Transthyretin Amyloidosis ATTR-CM ATTRv-PN ATTR ATTR-Mixed hATTR
Interventions
DRUG
No Results Yet
NCT06463028 | RECRUITING | PHASE2
40 Participants

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-12-12
Completion: 2028-09-30
Conditions
Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT06461455 | COMPLETED | NA
95 Participants

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-07-26
Completion: 2024-12-31
Conditions
Presbyopia Astigmatism
Interventions
DEVICE
Results Available
NCT06455384 | RECRUITING | NA
170 Participants

The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-28
Completion: 2027-03-31
Conditions
Cardiac Conditions Connective Tissue Diseases Retinal Disease Epilepsy in Children Neurodevelopmental Disorders Cancer Polyposis
Interventions
BEHAVIORAL
No Results Yet
NCT06451250 | COMPLETED | NA
42 Participants

Providing Evidence-Based Approaches for Caregiver Stress Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-02-02
Completion: 2025-12-19
Conditions
Caregiving Stress Dementia
Interventions
OTHER
No Results Yet
NCT06445023 | RECRUITING | PHASE3
915 Participants

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-07-11
Completion: 2026-10-31
Conditions
Chronic Spontaneous Urticaria
Interventions
BIOLOGICAL
No Results Yet
NCT06439082 | RECRUITING | PHASE3
315 Participants

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-10-24
Completion: 2029-03-23
Conditions
Sickle Cell Disease
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06428409 | RECRUITING | PHASE1/PHASE2
220 Participants

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-20
Completion: 2029-10-16
Conditions
Colorectal Cancer Pancreatic Ductal Adenocarcinoma Biliary Tract Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06427876 | RECRUITING
40 Participants

Fasenra Pediatric Japan Post-Marketing Study(PMS)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-07-16
Completion: 2027-03-17
Conditions
Bronchial Asthma
No Results Yet
NCT06419920 | RECRUITING | NA
35 Participants

Prosthetic Performance Enhancement Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-26
Completion: 2026-11-30
Conditions
Amputation Lower Limb Amputation Below Knee (Injury) Lower Limb Amputation Above Knee (Injury) Lower Limb Amputation at Ankle (Injury) Lower Limb Amputation Knee Lower Limb Amputation at Hip (Injury)
Interventions
OTHER
No Results Yet
NCT06416969 | RECRUITING | EARLY_PHASE1
24 Participants

Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-01
Completion: 2027-04-01
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06413797 | COMPLETED | NA
928 Participants

Little Cigar and Cigarillo Warnings for Youth

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-07-18
Completion: 2024-11-25
Conditions
Little Cigars and Cigarillos (LCC) Use
Interventions
BEHAVIORAL
Results Available
NCT06413706 | RECRUITING | PHASE2
45 Participants

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-10-25
Completion: 2027-11-30
Conditions
Glioma
Interventions
DRUG
No Results Yet
NCT06410443 | RECRUITING | NA
60 Participants

Efficacy and Safety of Local Glucocorticoids for the Treatment of Acute Radiation-Induced Intestinal Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-08-01
Completion: 2026-12-31
Conditions
Radiation-Induced Intestinal Injury
Interventions
DRUG
No Results Yet
NCT06404437 | ACTIVE_NOT_RECRUITING
100 Participants

Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-03-09
Completion: 2024-05-22
Conditions
Aortic Valve Stenosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06396650 | NOT_YET_RECRUITING | NA
40 Participants

Assessment of Fall Risks and Subject-specific Training for Fall Reduction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-31
Completion: 2029-04-30
Conditions
Fall Risk
Interventions
DEVICE
No Results Yet
NCT06395506 | RECRUITING | NA
60 Participants

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-10-29
Completion: 2028-05-31
Conditions
Breast Cancer Breast Cancer Female Muscle Weakness
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06394323 | COMPLETED | NA
132 Participants

Supporting Oral Pre-exposure Prophylaxis Decision Making Among Pregnant Women in Lilongwe, Malawi

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-08-06
Completion: 2025-02-07
Conditions
HIV Prevention
Interventions
BEHAVIORAL
Results Available
NCT06376123 | COMPLETED
40 Participants

Nomogram for Prediction of Alveolo-arterial Gradient During One-lung Ventilation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-06-01
Completion: 2024-11-01
Conditions
One-lung Ventilation
No Results Yet
NCT06365216 | ACTIVE_NOT_RECRUITING | PHASE2
80 Participants

ALS Phase II Study of NX210c

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-10-25
Completion: 2026-02-01
Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG
No Results Yet
NCT06360289 | RECRUITING
500 Participants

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2024-04-25
Completion: 2027-12-01
Conditions
Hereditary Amyloidosis, Transthyretin-Related Asymptomatic Carrier State
Interventions
OTHER
No Results Yet
NCT06357377 | NOT_YET_RECRUITING | PHASE1
12 Participants

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-31
Completion: 2026-10-31
Conditions
Pediatric Tumor of CNS Pediatric Tumor of Brain Diffuse Midline Glioma, H3 K27M-Mutant Pediatric Tumor of Brain Stem Pineocytoma Choroid Plexus Carcinoma, Childhood Spinal Cord Tumor High Grade Glioma
Interventions
DRUG
No Results Yet
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