Clinical Trials
Showing trials with last updates posted in 2025.
8600
Participants
Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-03
Completion:
2029-01-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
484
Participants
Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-12-28
Completion:
2026-02-03
Conditions
Persistent Atrial Fibrillation
Interventions
DEVICE
DRUG
No Results Yet
90
Participants
Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration on Right Lobe Donor Hepatectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-01
Completion:
2024-11-30
Conditions
Liver Regeneration
Ursodeoxycholic Acid
Partial Liver Resection
Interventions
DRUG
OTHER
No Results Yet
36
Participants
A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-06-28
Completion:
2026-06-30
Conditions
Acute Pancreatitis
Interventions
DRUG
No Results Yet
75
Participants
Promoting Intergenerational Health in Rural Kentuckians With Diabetes (PIHRK'D)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-01
Completion:
2025-12-31
Conditions
Diabetes Mellitus, Type 2
Interventions
BEHAVIORAL
No Results Yet
340
Participants
A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-12-31
Completion:
2027-07-30
Conditions
Essential Thrombocythemia
Interventions
DRUG
No Results Yet
23
Participants
Characterization of the Central and Peripheral Wavefront Aberration Profile in Pediatric Myopic Subjects
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2023-11-16
Completion:
2025-08-11
Conditions
Myopia
Interventions
DIAGNOSTIC_TEST
No Results Yet
99
Participants
An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-20
Completion:
2027-06-30
Conditions
Mucopolysaccharidosis II
Interventions
DRUG
No Results Yet
470
Participants
TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-13
Completion:
2028-01-31
Conditions
Alcohol Use Disorder
Alcohol Drinking
Alcohol-Related Disorders
Interventions
BEHAVIORAL
No Results Yet
20
Participants
Implementing and Evaluating the Integration of Physical Activity Into a Major Health System and Connecting Patients to Physical Activity Programs.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-08-03
Completion:
2023-09-05
Conditions
Chronic Disease
Exercise
Physical Activity
Interventions
OTHER
BEHAVIORAL
No Results Yet
21
Participants
Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-11-10
Completion:
2027-10-01
Conditions
Ovarian Clear Cell Carcinoma
Interventions
DRUG
No Results Yet
232
Participants
A Study to Learn How Safe the Study Treatment Actinium-225-macropa-pelgifatamab (BAY3546828) is, How it Affects the Body, How it Moves Into, Through and Out of the Body, and About Its Anticancer Activity in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-20
Completion:
2027-06-08
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
DRUG
No Results Yet
318
Participants
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-07
Completion:
2030-08-31
Conditions
Primary Biliary Cholangitis
Interventions
DRUG
No Results Yet
60
Participants
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-16
Completion:
2026-04-30
Conditions
Anxiety
Autism Spectrum Disorder
Separation Anxiety
Generalized Anxiety Disorder
Social Anxiety Disorder of Childhood
Interventions
BEHAVIORAL
OTHER
No Results Yet
100
Participants
Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-08
Completion:
2026-01-31
Conditions
Overweight
Obesity
Interventions
OTHER
DIETARY_SUPPLEMENT
No Results Yet
100
Participants
MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-04
Completion:
2028-12-01
Conditions
Multiple Myeloma
Interventions
PROCEDURE
BIOLOGICAL
DRUG
OTHER
No Results Yet
150
Participants
Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-11-01
Completion:
2026-02-01
Conditions
Burning Mouth Syndrome
Interventions
DRUG
DIETARY_SUPPLEMENT
OTHER
RADIATION
No Results Yet
48
Participants
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-07-20
Completion:
2025-09-15
Conditions
Cardiovascular Disorder
Coronary Artery Disease
Diabetes Mellitus
Obesity-Related Malignant Neoplasm
Interventions
OTHER
PROCEDURE
No Results Yet
60
Participants
Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-27
Completion:
2024-07-23
Conditions
Pneumothorax
Interventions
DIAGNOSTIC_TEST
No Results Yet
168
Participants
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-10-13
Completion:
2026-04-30
Conditions
Triple Negative Breast Cancer
Diffuse Large B Cell Lymphoma
Follicular Lymphoma
Lymphoma, Non-Hodgkin
Mantle Cell Lymphoma
Bladder Cancer
Uveal Melanoma, Recurrent
Cervix Cancer
Carcinoma in Situ
Head and Neck Squamous Cell Carcinoma
Skin Cancer
Metastatic Cancer
Tumor, Solid
Tumor Recurrence
Interventions
DRUG
No Results Yet
30
Participants
Intratumoral PH-762 for Cutaneous Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-11-07
Completion:
2026-01-31
Conditions
Malignant Melanoma of Skin
Squamous Cell Carcinoma of the Skin
Merkel Cell Carcinoma of Skin
Interventions
DRUG
No Results Yet
70
Participants
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2023-08-30
Completion:
2026-12-31
Conditions
Heart Failure, Diastolic
Peripheral Arterial Disease
Overweight and Obesity
Heart Failure, Systolic
No Results Yet
22
Participants
Study of Mogamulizumab With DA-EPOCH or CHOEP in Patients With Aggressive T-cell Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-09
Completion:
2026-11-30
Conditions
T Cell Lymphoma
T-cell Lymphoma
Interventions
DRUG
No Results Yet
24
Participants
A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-10-06
Completion:
2024-12-13
Conditions
Pancreatic Ductal Adenocarcinoma
Gastroesophageal Adenocarcinoma
Glioblastoma Multiforme
Interventions
DRUG
No Results Yet
5
Participants
Study With NVDX3 for Treatment of Low Grade Degenerative Lumbar Spondylolisthesis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-10-12
Completion:
2026-04-18
Conditions
Degenerative Lumbar Spondylolisthesis
Interventions
DRUG
No Results Yet
63
Participants
Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-11
Completion:
2026-02-28
Conditions
Diabetic Macular Edema
Interventions
DRUG
No Results Yet
1200
Participants
Quitxt Mobile Text Messaging Cessation Research Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-31
Completion:
2028-08-31
Conditions
Smoking Cessation
Interventions
BEHAVIORAL
OTHER
No Results Yet
735
Participants
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-08-08
Completion:
2032-06-01
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Leukemia, Chronic Lymphocytic
Small-Cell Lymphoma
Lymphoma, Small Lymphocytic
CLL
SLL
Interventions
DRUG
BIOLOGICAL
No Results Yet
120
Participants
Hearing Program in Primary Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-15
Completion:
2026-01-15
Conditions
Deafness
Interventions
BEHAVIORAL
No Results Yet
41
Participants
Evaluation of Metabolic Syndrome, Frailty, Locomotive Syndrome, Balance and Physical Fitness in Elderly Individuals
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2023-06-01
Completion:
2024-11-01
Conditions
Geriatrics
Fragility
Locomotor
Physical Fitness
Balance
Interventions
OTHER
No Results Yet
22
Participants
Perioperative Continuous Glucose Monitoring
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-08-04
Completion:
2024-05-21
Conditions
Diabetes Mellitus
Interventions
DEVICE
OTHER
5
Participants
Post-Brain Injury Walking and Balance Recovery Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-08-18
Completion:
2025-04-04
Conditions
Acquired Brain Injury
Stroke
Traumatic Brain Injury
Interventions
DEVICE
No Results Yet
60
Participants
Brain Health Program for Older Adults With Subjective Cognitive Decline
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-01-16
Completion:
2025-11-07
Conditions
Memory Loss (Excluding Dementia)
Healthy Lifestyle
Risk Reduction Behavior
Interventions
BEHAVIORAL
No Results Yet
8
Participants
Liver Biopsy Following Gene Therapy For Hemophilia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-31
Completion:
2030-01-31
Conditions
Hemophilia A
Hemophilia B
Interventions
PROCEDURE
No Results Yet
190
Participants
Comparison Between Local Radiotherapy Alone or Combined With Obinutuzumab in Early Stage Follicular Lymphoma: the GAZEBO Trial From the Fondazione Italiana Linfomi
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-12-14
Completion:
2031-04-30
Conditions
Follicular Lymphoma
Interventions
RADIATION
OTHER
No Results Yet
92
Participants
Treatment of Peri-implant Mucositis by Sodium Hypochlorite Gel and Cross-linked Hyaluronic Acid Gel
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-06-06
Completion:
2025-07-01
Conditions
Peri-implant Mucositis
Mucositis Oral
Interventions
PROCEDURE
No Results Yet
21
Participants
Afimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-07-24
Completion:
2030-12-31
Conditions
Crohns Disease
Interventions
DRUG
No Results Yet
155
Participants
mHealth for Young Adult Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-15
Completion:
2025-02-28
Conditions
Survivorship
Cancer
Psychological Well-Being
Interventions
BEHAVIORAL
503
Participants
A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2023-07-05
Completion:
2026-06-05
Conditions
Metastatic Hormone-sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
614
Participants
Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-05-23
Completion:
2024-11-22
Conditions
Complicated Urinary Tract Infection
Acute Pyelonephritis
cUTI
AP
Interventions
DRUG
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