Clinical Trials

Showing trials with last updates posted in 2025.

NCT05456698 | ACTIVE_NOT_RECRUITING | PHASE2
31 Participants

Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-10-18
Completion: 2025-11-05
Conditions
Acute Lymphocytic Leukemia
Interventions
DRUG
No Results Yet
NCT05453903 | RECRUITING | PHASE1
200 Participants

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-10-04
Completion: 2026-10-30
Conditions
Leukemia, Myeloid, Acute
Interventions
DRUG
No Results Yet
NCT05447312 | ACTIVE_NOT_RECRUITING | NA
75 Participants

Adaptive Music Therapy for Psychosocial and Cognitive Functions of Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-12-01
Completion: 2025-11-07
Conditions
Stress, Psychological Executive Functions Loneliness Emotion Regulation Functional Abilities Well Being
Interventions
OTHER
No Results Yet
NCT05429983 | RECRUITING
60 Participants

Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2022-11-29
Completion: 2027-11-29
Conditions
Sleep Apnea, Obstructive
No Results Yet
NCT05424822 | ACTIVE_NOT_RECRUITING | PHASE1
167 Participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-08-18
Completion: 2025-10-31
Conditions
Lymphoma, Non-Hodgkin Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
DRUG
No Results Yet
NCT05416515 | COMPLETED | PHASE2
40 Participants

A Study of Fisetin to Treat Carpal Tunnel Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-10-09
Completion: 2024-12-31
Conditions
Carpal Tunnel Syndrome
Interventions
DRUG
NCT05412992 | TERMINATED | PHASE2
179 Participants

Evaluation of the Dexmedetomidine Transdermal Systems for Postoperative Analgesia Following Abdominoplasty

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-07-07
Completion: 2023-04-19
Conditions
Pain, Postoperative
Interventions
DRUG
No Results Yet
NCT05393674 | ACTIVE_NOT_RECRUITING | PHASE2
30 Participants

Fedratinib in Combination With Nivolumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-06-14
Completion: 2026-03-31
Conditions
Primary Myelofibrosis Secondary Myelofibrosis
Interventions
DRUG
No Results Yet
NCT05388708 | RECRUITING
550 Participants

ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-02-04
Completion: 2027-09-30
Conditions
Acute Respiratory Distress Syndrome Extracorporeal Membrane Oxygenation
Interventions
DEVICE OTHER
No Results Yet
NCT05371106 | RECRUITING
150 Participants

Mycotoxins in Mothers Milk in Israel

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2020-09-01
Completion: 2027-12-31
Conditions
Breastfeeding
Interventions
OTHER
No Results Yet
NCT05362201 | COMPLETED | NA
20 Participants

Application of the Visualization of Treatment Objective (VTO) Analyses in Fabricating Anterior Repositioning Splints

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-04-01
Completion: 2023-09-30
Conditions
Temporomandibular Joint Disorders
Interventions
PROCEDURE
No Results Yet
NCT05350761 | RECRUITING
500 Participants

Rare Tumors and Cancer Predisposition in Individuals and Families

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-03-10
Completion: 2035-12-31
Conditions
Cancer Hereditary Neoplasms Genetic Predisposition to Cancer Environment
No Results Yet
NCT05307874 | COMPLETED | PHASE1/PHASE2
56 Participants

Phase 1/2a Study of ICT01 Plus Low Dose SC IL-2 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-05-04
Completion: 2025-10-09
Conditions
Solid Tumor, Adult
Interventions
DRUG
No Results Yet
NCT05303519 | RECRUITING | PHASE2
125 Participants

Safusidenib Phase 2 Study in IDH1 Mutant Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-05
Completion: 2027-12-01
Conditions
Glioma Astrocytoma, Grade IV IDH1-mutant Glioma Astrocytoma, IDH-Mutant, Grade 3 Astrocytoma, IDH-Mutant, Grade 4
Interventions
DRUG
No Results Yet
NCT05301907 | COMPLETED
335 Participants

Survey Among Healthcare Professionals and MS Patients to Assess Their Understanding of RMP Materials

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-12-02
Completion: 2025-05-16
Conditions
Multiple Sclerosis
No Results Yet
NCT05280041 | COMPLETED | NA
80 Participants

Optimising an Online Self-help Program for Coping With the Loss of a Spouse

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-04-04
Completion: 2025-12-17
Conditions
Grief
Interventions
BEHAVIORAL
No Results Yet
NCT05256745 | RECRUITING | PHASE1/PHASE2
48 Participants

RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-06
Completion: 2026-12-31
Conditions
Cancer Related Cognitive Decline Non-metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT05254743 | RECRUITING | PHASE3
662 Participants

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-07-22
Completion: 2025-06-10
Conditions
Chronic Lymphocytic Leukemia Leukemia, Lymphocytic Leukemia, B-cell Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
NCT05225727 | COMPLETED | NA
123 Participants

Me & You-Tech: A Socio-Ecological Solution to Teen Dating Violence for the Digital Age

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-10-01
Completion: 2024-12-14
Conditions
Adolescent Behavior Interpersonal Relations Domestic Violence Physical Violence
Interventions
BEHAVIORAL
NCT05224323 | RECRUITING
50 Participants

Avalanche Phenomenon During Airways Opening in Acute Respiratory Distress Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2022-03-01
Completion: 2026-09-30
Conditions
Acute Respiratory Distress Syndrome
Interventions
OTHER
No Results Yet
NCT05220410 | COMPLETED | PHASE2
20 Participants

The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-03-28
Completion: 2025-05-12
Conditions
Treatment Resistant Depression Suicidal Ideation
Interventions
DRUG
No Results Yet
NCT05182125 | COMPLETED | PHASE1
34 Participants

Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of HIV-1 Chimp Adenovirus Vaccines Expressing Clade C gp140 & CH505TF gp120 Protein Boost in HIV-uninfected Adult.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-11-25
Completion: 2023-08-21
Conditions
HIV Infections
Interventions
BIOLOGICAL
NCT05181722 | ACTIVE_NOT_RECRUITING | NA
196 Participants

Evaluating the Use of Patient Navigation to Promote Timely Diagnostic Evaluation During the COVID-19 Pandemic

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-07-18
Completion: 2026-12-31
Conditions
Breast Cancer
Interventions
OTHER
No Results Yet
NCT05179603 | TERMINATED | PHASE2
14 Participants

A Study of SAR444245 With or Without Other Anticancer Therapies for the Treatment of Adults and Adolescents With Relapsed or Refractory B Cell Lymphoma (Master Protocol) [Pegathor Lymphoma 205]

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-12-07
Completion: 2023-09-14
Conditions
Classic Hodgkin Lymphoma Diffuse Large B-cell Lymphoma
Interventions
DRUG
NCT05173818 | COMPLETED | PHASE2
20 Participants

Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-06-28
Completion: 2025-08-01
Conditions
Persistent Post-concussive Syndrome Concussion Post Syndrome
Interventions
DRUG
No Results Yet
NCT05165940 | NOT_YET_RECRUITING | NA
40 Participants

Facilitating Transition to Recommended PTSD Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-01
Completion: 2027-05-03
Conditions
PTSD
Interventions
BEHAVIORAL
No Results Yet
NCT05162170 | COMPLETED
633 Participants

Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2019-10-02
Completion: 2022-12-05
Conditions
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
No Results Yet
NCT05160636 | ACTIVE_NOT_RECRUITING
999 Participants

A Study to Look at the Health Outcomes of Patients With COVID-19 and Influenza

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2022-01-31
Completion: 2026-02-28
Conditions
COVID-19 Coronavirus Disease 2019 Influenza
Interventions
BIOLOGICAL
No Results Yet
NCT05160584 | RECRUITING
300 Participants

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-11-18
Completion: 2028-04-30
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
OTHER
No Results Yet
NCT05141357 | TERMINATED | PHASE2
5 Participants

A Study of HBI-8000 (Tucidinostat) With Pembrolizumab in Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-02-15
Completion: 2023-04-19
Conditions
Non Small Cell Lung Cancer
Interventions
DRUG
NCT05139017 | RECRUITING | PHASE2/PHASE3
290 Participants

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-01-14
Completion: 2027-09-24
Conditions
DLBCL Diffuse Large B-Cell Lymphoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05133479 | ACTIVE_NOT_RECRUITING | NA
241 Participants

Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-01-01
Completion: 2026-06-30
Conditions
Language Disorders in Children
Interventions
BEHAVIORAL
No Results Yet
NCT05130827 | ACTIVE_NOT_RECRUITING | PHASE2
17 Participants

Study of Plinabulin and Pegfilgrastim in People With Multiple Myeloma Undergoing an Autologous Hematopoietic Stem Cell Transplant (AHCT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-12-21
Completion: 2026-11-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05130437 | RECRUITING | PHASE1/PHASE2
50 Participants

A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-11-09
Completion: 2029-12-04
Conditions
Propionic Acidemia
Interventions
BIOLOGICAL
No Results Yet
NCT05128942 | TERMINATED | PHASE2
67 Participants

A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children Aged 2-17 Years With CAH

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-12-10
Completion: 2025-01-31
Conditions
Congenital Adrenal Hyperplasia 21-OHD
Interventions
DRUG
NCT05128825 | RECRUITING | PHASE2
170 Participants

A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-02-17
Completion: 2026-12-01
Conditions
High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Interventions
DRUG
No Results Yet
NCT05122988 | COMPLETED
2606 Participants

Facing Adverse Childhood Experiences

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2021-10-28
Completion: 2024-05-01
Conditions
Adverse Childhood Experiences
No Results Yet
NCT05104723 | ENROLLING_BY_INVITATION | PHASE1/PHASE2
20 Participants

Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-08-12
Completion: 2026-01-01
Conditions
Chronic Granulomatous Disease Inflammatory Gastrointestinal Disease Inflammatory Skin Disease Inflammatory Lung Disease
Interventions
DRUG
No Results Yet
NCT05098613 | RECRUITING | PHASE1
68 Participants

Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-12-21
Completion: 2026-12-31
Conditions
Non-Hodgkin Lymphoma B-cell Non-Hodgkin Lymphoma (B-NHL) Mantle Cell Lymphoma (MCL) CNS Lymphoma
Interventions
DRUG
No Results Yet
NCT05097534 | ENROLLING_BY_INVITATION | NA
150 Participants

A Comprehensive Community Approach for Diabetes Prevention and Care for a Vulnerable Population in Galveston

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2021-12-07
Completion: 2025-10-31
Conditions
Diabetes Mellitus, Type 2
Interventions
OTHER
No Results Yet
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