Clinical Trials
Showing trials with last updates posted in 2025.
55
Participants
Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-11-29
Completion:
2028-12-31
Conditions
Neurofibromatosis 1
Interventions
DRUG
No Results Yet
283
Participants
Early Cognitive Intervention in Delirium
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-02-09
Completion:
2024-11-14
Conditions
Delirium
Cognitive Decline
Dementia
Interventions
BEHAVIORAL
490
Participants
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-04-05
Completion:
2029-01-04
Conditions
Hematologic Malignancies
Waldenstroms Macroglobulinaemia
Non-Hodgkins Lymphoma
Chronic Lymphocytic Leukaemia
Interventions
DRUG
No Results Yet
643
Participants
Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-01-19
Completion:
2025-01-31
Conditions
Oral Cancer
Oropharyngeal Cancer
Head and Neck Cancer
Interventions
OTHER
No Results Yet
396
Participants
Community Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District, Bong County, Liberia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-09-30
Completion:
2026-02-28
Conditions
Malaria
No Results Yet
60
Participants
Cardiovascular Rehabilitation and Reeducation (CVRR) in Patients With Cardiac Pathologies and the 6-minute Stepper Test
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-01-13
Completion:
2022-04-28
Conditions
Cardiac Disease
Interventions
OTHER
No Results Yet
40
Participants
fNIRS in Pediatric Hearing Aids
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-09-09
Completion:
2027-09-30
Conditions
Hearing Loss
Interventions
DIAGNOSTIC_TEST
No Results Yet
175
Participants
Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2020-12-01
Completion:
2025-01-25
Conditions
Coronary Heart Disease
Depression
Interventions
OTHER
No Results Yet
425
Participants
Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-04-01
Completion:
2025-11-21
Conditions
Mycobacterium Infections, Nontuberculous
Interventions
DRUG
No Results Yet
5000
Participants
Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-29
Completion:
2028-01-31
Conditions
Peripheral Vascular Diseases
Interventions
DEVICE
No Results Yet
1000000
Participants
Identification of Outcome Relevant Indicators in Routine Data
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2020-12-03
Completion:
2025-12-31
Conditions
Anesthesiological Risk Reduction
Intensive Care Risk Reduction
No Results Yet
144
Participants
A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-11-12
Completion:
2027-10-01
Conditions
Prostatic Neoplasms
Adenocarcinoma
Interventions
DRUG
RADIATION
No Results Yet
390
Participants
Monitoring the Weight Evolution Using a Connected Scale
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-25
Completion:
2026-12-31
Conditions
Bariatric Surgery
Long Term Follow-Up
Weight Regain
Interventions
OTHER
No Results Yet
221
Participants
ON-SCENE Initiation of Extracorporeal CardioPulmonary Resuscitation During Refractory Out-of-Hospital Cardiac Arrest
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-10-15
Completion:
2025-07-01
Conditions
Extracorporeal Membrane Oxygenation
Cardiac Arrest
Interventions
PROCEDURE
No Results Yet
200
Participants
The Role of 18F-FDG-PET for Staging and Prognostication
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2020-10-30
Completion:
2023-10-26
Conditions
Mantle Cell Lymphoma
No Results Yet
957
Participants
Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-11-17
Completion:
2024-12-20
Conditions
Gastrointestinal Neoplasms
Esophagogastric Junction
Interventions
DRUG
No Results Yet
257
Participants
A Study of Usage of Brigatinib in the Treatment of Adult Participants for Approved Indications In South Korea
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-05
Completion:
2026-08-26
Conditions
Carcinoma, Non-Small-Cell Lung
Anaplastic Lymphoma Kinase
Interventions
OTHER
No Results Yet
843
Participants
Strengthening Families Living With HIV in Kenya
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-09-28
Completion:
2025-07-15
Conditions
ART
Hiv
Trust
Depression, Anxiety
PTSD
Adherence, Medication
Interventions
BEHAVIORAL
No Results Yet
28
Participants
Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-04-15
Completion:
2031-12-30
Conditions
Primary Hyperoxaluria Type 1
End Stage Renal Disease
Interventions
DRUG
No Results Yet
100
Participants
Periarticular Injection Versus Popliteal Block
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-07-13
Completion:
2026-09-30
Conditions
Foot Surgery
Ankle Surgery
Interventions
DRUG
No Results Yet
48
Participants
Copanlisib Plus Venetoclax in R/R DLBCL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-09-08
Completion:
2026-04-01
Conditions
Diffuse Large B Cell Lymphoma
Relapsed Diffuse Large B-Cell Lymphoma
Refractory Diffuse Large B-Cell Lymphoma
Interventions
DRUG
No Results Yet
1500
Participants
ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2020-11-23
Completion:
2030-09-01
Conditions
Transthyretin-Mediated Amyloidosis
ATTR Amyloidosis
No Results Yet
540
Participants
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-09-20
Completion:
2032-10-25
Conditions
Primary IgA Nephropathy
Interventions
DRUG
No Results Yet
68
Participants
Genome-Wide Assocation Study in Patients With Brain Injury Associated Fatigue and Altered Cognition (BIAFAC)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-21
Completion:
2024-01-18
Conditions
Traumatic Brain Injury
No Results Yet
985
Participants
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-10-26
Completion:
2025-09-17
Conditions
Multiple Sclerosis, Primary Progressive
Interventions
DRUG
No Results Yet
100
Participants
Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-09-15
Completion:
2021-06-02
Conditions
Influenza
Interventions
BIOLOGICAL
59
Participants
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-02-16
Completion:
2024-10-17
Conditions
Progressive Supranuclear Palsy (PSP)
Interventions
DRUG
No Results Yet
5176
Participants
Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-10-05
Completion:
2023-05-31
Conditions
Peripheral Artery Disease
Interventions
BEHAVIORAL
1000
Participants
Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-08
Completion:
2032-03-31
Conditions
Breast Cancer
Digestive Cancer
Gynecologic Cancer
Circulating Tumor DNA
Exosomes
Interventions
DIAGNOSTIC_TEST
No Results Yet
26
Participants
Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-07-12
Completion:
2023-06-30
Conditions
Post-Mastectomy Chronic Pain Syndrome
Interventions
PROCEDURE
611
Participants
A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-10-08
Completion:
2027-02-01
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
DRUG
No Results Yet
63
Participants
Brain Activation and Satiety in Children 2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-01-28
Completion:
2025-02-21
Conditions
Childhood Obesity
Interventions
BEHAVIORAL
DRUG
No Results Yet
230
Participants
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2020-07-31
Completion:
2028-07-27
Conditions
Breast Adenocarcinoma
HER2-Positive Breast Carcinoma
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Interventions
PROCEDURE
No Results Yet
25
Participants
Phase II Panitumumab-IRDye800 in Head & Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-04-02
Completion:
2030-12-31
Conditions
Head and Neck Cancer
Interventions
DRUG
No Results Yet
116
Participants
Baroreflex Sensitivity in Patients Undergoing Ablation of Atrial Fibrillation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-22
Completion:
2025-11-13
Conditions
Paroxysmal Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
1100
Participants
Natural History of Autosomal Dominant Hearing Loss
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-02-09
Completion:
2029-08-21
Conditions
Hearing Loss
No Results Yet
74
Participants
Academic-Community EPINET (AC-EPINET)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-03-16
Completion:
2025-07-29
Conditions
Schizophrenia
Schizoaffective Disorder
Schizophreniform Disorders
Major Depression With Psychotic Features
Bipolar Disorder With Psychotic Features
Interventions
OTHER
No Results Yet
45
Participants
Analgesic and Subjective Effects of Terpenes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-12-15
Completion:
2025-11-12
Conditions
Pain
Abuse, Drug
Interventions
DRUG
No Results Yet
82
Participants
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-08-24
Completion:
2026-04-02
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
800
Participants
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-30
Completion:
2038-06-30
Conditions
Familial Cancer
BRCA1-Associated Protein-1 (BAP1) Mutations
Tumor Predisposition Syndrome (TPDS)
Mesothelioma
No Results Yet
Showing 40 trials per page